Verastem - Targeting cancer stem cells

Thursday, Jan 17 2013 by

Jan 17th 2013 - Edison Investment Research today published a report on Verastem entitled "Targeting Cancer Stem Cells". In summary, the report says:

Verastem will shortly begin a series of studies that should provide definitive proof-of-concept for its cancer stem cell (CSC) hypothesis. The company plans to initiate Phase II trials of its lead compound, VS-6063, a FAK inhibitor that preclinical tests suggest is CSC-directed in mesothelioma and ovarian cancer. It also expects to advance VS-4718 and VS-5584, two CSC-directed compounds, into human clinical studies and decide on suitable indications thereafter. Verastem is well funded (>$90m cash) to reach the significant value inflection points associated with the results of these studies.




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