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The S&P 500 and the Nasdaq slipped from record levels in volatile trading on
Wednesday as Reddit forum turned their focus to cannabis stocks while investors
looked to a speech by Federal Reserve Chair Jerome Powell in the afternoon.  .N 
    At 13:56 ET, the Dow Jones Industrial Average  .DJI  was up 0.07% at
31,396.29. The S&P 500  .SPX  was down 0.05% at 3,909.35 and the Nasdaq
Composite  .IXIC  was down 0.17% at 13,983.967.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Under Armour   UAA.N , up 8.8%
 ** Twitter Inc  TWTR.N , up 8.8%
 ** Under Armour   UA.N , up 7.8%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Akamai Tech Inc  AKAM.O , down 11.6%
 ** FMC Corp  FMC.N , down 8%
 ** Interpublic Group of Companies  IPG.N , down 6%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** India Globalization Capital  IGC.N , up 48.9%
 ** Cootek (Cayman)  CTK.N , up 34.6%
 ** Transenterix  TRXC.N , up 27.4%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Cloopen Group Holding  RAAS.N , down 30.6%
 ** VolitionRx  VNRX.N , down 17%
 ** SQZ Biotechnologies  SQZ.N , down 15.4%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Anchiano Therapeutics  ANCN.O , up 255.4%
 ** Biopath Holdings  BPTH.O , up 164%
 ** GreenVision Acquisition  GRNVU.O , up 99.6%
 
 The top Nasdaq  .PL.O  percentage losers:
 ** Panbela Therapeutics  PBLA.O , down 25.9%
 ** INSU Acquisition Corp. III  IIIIW.O , down 24.3%
 
 
 ** Twitter  TWTR.N : up 8.8%
 BUZZ-Twitter hits 7-yr high on strong results  urn:newsml:reuters.com:*:nL4N2KG3WP
 
 ** Match Group  MTCH.O : up 8.6%
 BUZZ-Rises on deal to buy S. Korean social media co Hyperconnect  urn:newsml:reuters.com:*:nL4N2KG2SR
 
 ** Plains All American  PAA.O : down 9.1%
 BUZZ-Down as Q4 oil pipeline volumes drop  urn:newsml:reuters.com:*:nL4N2KG3XG
 
 ** Cassava Sciences Inc  SAVA.O : down 12.0%
 BUZZ-Down on $200 mln capital raise  urn:newsml:reuters.com:*:nL4N2KG31U
 
 ** Forest Road Acquisition Corp  FRX.N : up 5.6%
 BUZZ-Surges on SPAC deal to take Beachbody, Myx public urn:newsml:reuters.com:*:nL1N2KG0WV
 
 ** OLB Group Inc  OLB.O : up 34.8%
 BUZZ-Surges after offering cryptocurrency payment options  urn:newsml:reuters.com:*:nL4N2KG37Z
 
 ** Panbela Therapeutics  PBLA.O : down 25.9%
 BUZZ-Down on 'partial clinical hold' on cancer drug study  urn:newsml:reuters.com:*:nL4N2KG3JM
 
 ** Turtle Beach  HEAR.O : up 2.7%
 BUZZ-Turtle Beach: Rises on upbeat full-year forecast  urn:newsml:reuters.com:*:nL4N2KG3M4
 
 ** Gamida Cell  GMDA.O : up 27.8%
 BUZZ-Soars on positive data from late-stage cancer therapy study  urn:newsml:reuters.com:*:nL4N2KG3CX
 
 ** Interpublic Group  IPG.N : down 6.0%
 BUZZ-Down on weak Q4 results as pandemic continues to weigh  urn:newsml:reuters.com:*:nL4N2KG3RC
 
 ** Alteryx Inc  AYX.N : down 15.4%
 BUZZ-Falls on weak Q1, full-year outlook  urn:newsml:reuters.com:*:nL4N2KG3T3
 
 ** Treehouse Foods  THS.N : up 17.8%
 BUZZ-Up as activist investor picks stake, pushes for co's sale  urn:newsml:reuters.com:*:nL4N2KG3TC
 
 ** I-Mab  IMAB.O : up 7.5%
 BUZZ-Rises on China nod for tumor treatment study  urn:newsml:reuters.com:*:nL4N2KG3VL
 
 ** Viant Technology  DSP.O : up 82.0%
 BUZZ-Jumps 76% in Nasdaq debut  urn:newsml:reuters.com:*:nL4N2KG3Z7
 
 ** National Research Corp  NRC.O : down 2.9%
 BUZZ-Falls on lower Q4 profit  urn:newsml:reuters.com:*:nL4N2KG408
 
  ** Criteo  CRTO.O : up 24.9%
 BUZZ-Surges on upbeat Q4 results  urn:newsml:reuters.com:*:nL4N2KG3ZQ
 
  ** Mesa Air Group  MESA.O : up 26.2%
 BUZZ-Surges on Q1 revenue, profit beat  urn:newsml:reuters.com:*:nL4N2KG42D
 
   ** Regulus  RGLS.O : up 0.3%
 BUZZ-Rises on completing enrollment of first group in kidney drug study
 urn:newsml:reuters.com:*:nL4N2KG44E
 
   ** Enphase Energy  ENPH.O : up 6.6%
 BUZZ-Hits record high as six brokerages raise PT on upbeat results  urn:newsml:reuters.com:*:nL4N2KG448
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   up 0.19%
 Consumer Discretionary   .SPLRCD   down 1.07%
 Consumer Staples         .SPLRCS   down 0.29%
 Energy                   .SPNY     up 1.56%
 Financial                .SPSY     up 0.31%
 Health                   .SPXHC    up 0.13%
 Industrial               .SPLRCI   down 0.07%
 Information Technology   .SPLRCT   down 0.39%
 Materials                .SPLRCM   up 0.02%
 Real Estate              .SPLRCR   up 0.30%
 Utilities                .SPLRCU   down 0.07%
 
 (Compiled by Arundhati Sarkar in Bengaluru)
 ((Arundhati.Sarkar@thomsonreuters.com; twitter.com/Arundhati_05; +1 646 223
8780 Ext: 2776))