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The S&P 500 and the Nasdaq slipped from record levels in volatile trading on
Wednesday as Reddit forum turned their focus to cannabis stocks while investors
looked to a speech by Federal Reserve Chair Jerome Powell in the afternoon.  .N 
    At 13:17 ET, the Dow Jones Industrial Average  .DJI  was up 0.06% at
31,393.1. The S&P 500  .SPX  was down 0.19% at 3,903.95 and the Nasdaq Composite
 .IXIC  was down 0.23% at 13,975.221.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Under Armour  UAA.N , up 8.4%
 ** Enphase Energy  ENPH.O , up 8%
 ** Twitter Inc  TWTR.N , up 7.7%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Akamai Tech Inc  AKAM.O , down 11.4%
 ** FMC Corp  FMC.N , down 7.9%
 ** Hanesbrands  HBI.N , down 6.6%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** India Globalization Capital  IGC.N , up 45%
 ** Atlas Crest Investment Corp  ACIC.N , up 28.4%
 ** Globalstar Inc  GSAT.N , up 26%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Cloopen Group Holding  RAAS.N , down 30.3%
 ** VolitionRx  VNRX.N , down 17%
 ** Youdao Inc  DAO.N , down 15.7%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Biopath Holdings  BPTH.O , up 229%
 ** GreenVision Acquisition Corp  GRNVU.O , up 179%
 ** Clever Leaves Holdings Inc  CLVRW.O , up 95.7%
 
 The top Nasdaq  .PL.O  percentage losers:
 ** Panbela Therapeutics  PBLA.O , down 24.1%
 ** Sino-Global Shipping America  SINO.O , down 24%
 
 
 
 ** Cassava Sciences Inc  SAVA.O : down 13.1%
 BUZZ-Down on $200 mln capital raise  urn:newsml:reuters.com:*:nL4N2KG31U
 
 ** Forest Road Acquisition Corp  FRX.N : up 4.5%
 BUZZ-Surges on SPAC deal to take Beachbody, Myx public urn:newsml:reuters.com:*:nL1N2KG0WV
 
 ** OLB Group Inc  OLB.O : up 46.3%
 BUZZ-Surges after offering cryptocurrency payment options  urn:newsml:reuters.com:*:nL4N2KG37Z
 
 ** Panbela Therapeutics  PBLA.O : down 24.1%
 BUZZ-Down on 'partial clinical hold' on cancer drug study  urn:newsml:reuters.com:*:nL4N2KG3JM
 
 ** Turtle Beach  HEAR.O : up 1.8%
 BUZZ-Rises on upbeat full-year forecast  urn:newsml:reuters.com:*:nL4N2KG3M4
 
 ** Match Group  MTCH.O : up 9.0%
 BUZZ-Rises on deal to buy S. Korean social media co Hyperconnect  urn:newsml:reuters.com:*:nL4N2KG2SR
 
 ** Gamida Cell  GMDA.O : up 29.4%
 BUZZ-Soars on positive data from late-stage cancer therapy study  urn:newsml:reuters.com:*:nL4N2KG3CX
 
 ** Interpublic Group  IPG.N : down 6.0%
 BUZZ-Down on weak Q4 results as pandemic continues to weigh  urn:newsml:reuters.com:*:nL4N2KG3RC
 
 ** Alteryx Inc  AYX.N : down 15.4%
 BUZZ-Falls on weak Q1, full-year outlook  urn:newsml:reuters.com:*:nL4N2KG3T3
 
 ** Treehouse Foods  THS.N : up 16.5%
 BUZZ-Up as activist investor picks stake, pushes for co's sale  urn:newsml:reuters.com:*:nL4N2KG3TC
 
 
    
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   down 0.07%
 Consumer Discretionary   .SPLRCD   down 0.93%
 Consumer Staples         .SPLRCS   down 0.30%
 Energy                   .SPNY     up 1.60%
 Financial                .SPSY     up 0.24%
 Health                   .SPXHC    up 0.19%
 Industrial               .SPLRCI   down 0.06%
 Information Technology   .SPLRCT   down 0.29%
 Materials                .SPLRCM   up 0.04%
 Real Estate              .SPLRCR   up 0.25%
 Utilities                .SPLRCU   down 0.18%
 
 (Compiled by Arundhati Sarkar in Bengaluru)
 ((Arundhati.Sarkar@thomsonreuters.com; twitter.com/Arundhati_05; +1 646 223
8780 Ext: 2776))