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SVA - Sinovac Biotech News Story

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UPDATE 1-China considering mixing COVID-19 vaccines to boost protection rate

Sun 11th April, 2021 3:20pm
(Adds comments from Chinese top disease control official)
    BEIJING, April 11 (Reuters) - China's top disease control
official has said the country is formally considering mixing
COVID-19 vaccines, as a way of further boosting vaccine
    Available data shows Chinese vaccines lag behind others
including Pfizer  PFE.N  and Moderna  MRNA.O  in terms of
efficacy, but require less stringent temperature controls during
    The currently available vaccines "don't have very high rates
of protection", Gao Fu, the director of the Chinese Centers for
Disease Control and Prevention, told a conference in the Chinese
city of Chengdu on Saturday. 
    "Inoculation using vaccines of different technical lines is
being considered," he said.
    Gao said that taking steps to "optimise" the vaccine process
including changing the number of doses and the length of time
between doses was a "definite" solution to the efficacy issues.
    China has developed four domestic vaccines approved for
public use and an official said on Saturday that the country
will likely produce 3 billion doses by the end of the year. 
    A COVID-19 vaccine developed by China's Sinovac  SVA.O  was
found to have an efficacy rate of slightly above 50% in
Brazilian clinical trials. A separate study in Turkey said it
was 83.5% effective.
    No detailed efficacy data has been released on a vaccines
made by China's Sinopharm  1099.HK . It has said two vaccines
developed by its units are 79.4% and 72.5% effective
respectively, based on interim results.  
    Both vaccine makers have presented data on their COVID-19
vaccines indicating levels of efficacy in line with those
required by the World Health Organization, a WHO panel said in
    China has shipped millions of its vaccines abroad, and
officials and state media have fiercely defended the shots while
calling into question the safety and logistics capabilities of
other vaccines.
    "The global vaccine protection rate test data are both high
and low," Gao told state tabloid Global Times on Sunday. 
    "How to improve the protection rate of vaccines is a problem
that requires global scientists to consider," Gao said, adding
that mixing vaccines and adjusting immunisation methods are
solutions that he had proposed.

 (Reporting by Cate Cadell; additional writing by Ryan Woo;
editing by David Evans)
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