** BioCryst Pharma BCRX.O shares gain 2.4 pct to $6.29
after the drug developer ends merger agreement with Idera Pharma
IDRA.O
** Idera drops 8.8 pct to $1.25 after BCRX shareholders
disapprove merger on Tues urn:newsml:reuters.com:*:nBw9jw0x3a
** Cos announced merger in late Jan, where BCRX would own
51.6 pct of new co, and IDRA would own rest urn:newsml:reuters.com:*:nL4N1PH4LO
** BioCryst also provides update on APeX-2 trial of BCX735,
a treatment to reduce frequency of attacks in patients with
hereditary angioedema (HAE); says on track to come out with
efficacy and safety results from first 24 weeks of APeX-2 in H1
2019.
** BCRX also on track for a H119 initiation of a early stage
study for ALK-2 inhibitor program for treating an orthopedic
disorder
** Says completed enrollment in three dose cohorts in a
mid-stage trial to evaluate BCX735 as an acute treatment of HAE
** BioCryst expects 2018 net operating cash use in range of
$85 to $105 mln, up from previously guided $67 to $90 mln
** Through Tuesday's close, BCRX up 28 pct YTD, IDRA off 40
pct
(Reporting by Sruthi Shankar in Bengaluru)
((RM: sruthi.shankar.reuters.com@reuters.net))