** Shares of Paradigm Biopharmaceuticals PAR.AX rise as
much as 8.5% to A$1.313, their highest since Feb. 18
** The drug developer receives regulatory and ethics
approval from the Medicines and Healthcare products Regulatory
Agency (MHRA) in the United Kingdom urn:newsml:reuters.com:*:nASX8DtbFf
** Says it now has all the required approvals in place to
start activities in the UK for its global Phase 3 clinical trial
for treatment of knee osteoarthritis pain
** Shares mark their biggest intraday gain since March 10
** As of last close, stock down 35.8% this year
(Reporting by Himanshi Akhand in Bengaluru)
((Himanshi.Akhand@thomsonreuters.com;))