** Shares of Paradigm Biopharma PAR.AX rise as much as
23.8% to A$0.780, their highest level since Aug 21
** Shares of the Australian late-stage drug developer is on
track for their best day since Nov 3, 2021, if gains hold
** Says iPPS (injectable pentosan polysulfate sodium)
demonstrates preservation of cartilage in Phase 2 clinical trial
for knee osteoarthritis (OA)
** Says results, which indicate a treatment effect on OA
beyond the relief of symptoms, support iPPS as a blockbuster
opportunity
** About 3.7 mln shares change hands, about 5.7 times the
30-day average
** Stock down ~55% this year, as of last close
(Reporting by Sherin Sunny in Bengaluru)