** Shares of Paradigm Biopharmaceuticals PAR.AX surge as
much as 21.8% to A$1.535, their biggest intraday pct gain since
Aug 3
** Paradigm says primary end-point has been met for
injectable Pentosan Polysulfate Sodium (iPPS) drug in Phase 2
clinical trial urn:newsml:reuters.com:*:nASXfyS76
** iPPS is a semi-synthetic drug used to reduce pain in
patients with knee osteoarthritis
** Phase 2 clinical trial is designed to evaluate treatment
effects of iPPS associated with osteoarthritis-related pain,
inflammation, and disease progression - co
** "Top-line results are encouraging at day 56 and we look
forward to further data at six and 12 months," CEO Marco Polizzi
** Stock hits highest level since Aug 15
** Nearly 2.2 mln Paradigm shares change hands, vs the
30-day average volume of ~830,000 shares
** Stock down 32.7% this year, as of last close
(Reporting by Harish Sridharan in Bengaluru)
((harish.sridharan@thomsonreuters.com))