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Merck beats first-quarter expectations on Keytruda, Gardasil strength (updated)

(Adds share movement)
       April 27 (Reuters) - Drugmaker Merck & Co Inc  MRK.N  on
Thursday posted better-than-expected results for the first
quarter on the strength of its blockbuster cancer immunotherapy
Keytruda and human papillomavirus (HPV) vaccine Gardasil.
    Shares of the company rose 1.8% to $114.98 in premarket
trading after the drugmaker raised its full-year forecasts for
sales and earnings, citing strong global demand for its drugs.
    The company's revenue fell year-over-year due to a sharp,
but expected, drop in sales from COVID pill molnupiravir, and
rose more than 10% excluding that drug. 
    Merck's first-quarter sales fell to $14.5 billion from $15.9
billion last year. Analysts, on average, had expected sales of
$13.8 billion, according to Refinitiv data.
    Excluding items, Merck earned $1.40 per share, compared with
estimates of $1.32 per share.
    Keytruda sales rose 20% to $5.8 billion in the quarter,
topping the estimates of $5.6 billion. Gardasil sales rose 35%
to $2 billion, above expectations of $1.7 billion.
    Sales for COVID treatment molnupiravir - sold under the
brand name Lagevrio - fell to $392 million from $3.2 billion
last year. The company has said it expects just $1 billion of
molnupiravir sales this year.
    It forecast 2023 sales of $57.7 billion to $58.9 billion, up
from its previous forecast of $57.2 billion to $58.7 billion. It
now expects to earn $6.88 to $7 a share, from $6.80 to $6.95 per
share previously. 
    Earlier this month, Merck agreed to buy Prometheus
Biosciences Inc  RXDX.O  for about $10.8 billion, picking up a
promising experimental treatment for ulcerative colitis and
Crohn's disease and building up its presence in immunology.
    Merck has been looking for deals to protect itself from
eventual revenue loss as patents on Keytruda begin to expire
toward the end of the decade. The company reported nearly $21
billion in Keytruda sales last year.

 (Reporting by Michael Erman in New York, additional reporting
by ; editing by Diane Craft)
 ((michael.erman@thomsonreuters.com;))

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