(Updates)
** Shares of biotech co Prometheus Biosciences Inc RXDX.O
jump 185.8% to ~$103, hit record high; biggest pct gainer across
U.S. stock exchanges
** Co reports positive mid-stage data testing antibody
PRA023 in ulcerative colitis (UC) and Crohn's disease (CD)
treatment trials
** UC is an inflammatory bowel disease while CD is a type of
inflammatory bowel disease that causes ulcers in digestive tract
** PRA023 met the primary goal of higher clinical remission
vs placebo in UC trial; also met the secondary goal with
statistical significance - Co
** Co expects results from UC trial in Q2 2023
** Reduction in markers of inflammation and fibrosis was
observed between pre-treatment and post-treatment with PRA023 -
RXDX
** Co also says adverse events occurred in two patients in
the CD trial and included COVID-19, urinary tract infection and
fatigue, among other experienced symptoms
** Co intends to advance PRA023 to late-stage trial for UC,
CD in 2023
** Including session's gain, stock up 159.7% YTD
(Reporting by Pratik Jain in Bengaluru)
((Pratik.Jain@thomsonreuters.com;))