NASH drug developers fall after Eli Lilly's obesity drug shows liver scarring benefit

** Shares of NASH drug developers Madrigal Pharmaceuticals
 MDGL.O  fall ~10% to $220.76, Akero Therapeutics  AKRO.O  down
3.3% at $18.58 and 89Bio  ETNB.O  down ~2% at $8.19 
    ** Eli Lilly  LLY.N  reports mid-stage study data for its
obesity drug being tested in patients with a serious fatty liver
disease formerly known as NASH and now called metabolic
dysfunction-associated steatohepatitis 
    ** LLY's tirzepatide showed statistically significant
fibrosis or liver scarring improvement in patients with no
worsening of NASH, the secondary goal of the study, across all
tested dosages 
    ** "We see this as a strong outcome for LLY that
definitively links weight loss to fibrosis benefit, and we
expect shares of competitor, non-fibrosis-focused MASH names to
trade lower," Guggenheim analyst Seamus Fernandez wrote in a
note
    

 (Reporting by Mariam Sunny in Bengaluru)
 ((Mariam.ESunny@thomsonreuters.com;))

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