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Wall Street's main indexes fell sharply on Thursday as fresh evidence of a tight
labor market and hawkish comments from policymakers deepened fears of elevated
interest rates for longer than expected.  .N 
    At 10:34 a.m. ET, the Dow Jones Industrial Average  .DJI  was down 1.01% at
32,935.38. The S&P 500  .SPX  was down 1.04% at 3,812.97 and the Nasdaq
Composite  .IXIC  was down 1.13% at 10,340.39.
    The top three S&P 500  .PG.INX  percentage gainers:
    ** Lamb Weston Holdings Inc  LW.N , up 8.6%
    ** Western Digital Corp  WDC.O , up 4.7%
    ** Valero Energy Corp  VLO.N , up 4.3%
    The top three S&P 500  .PL.INX  percentage losers:
    ** Constellation Brands Inc  STZ.N , down 6.9%
    ** Walgreens Boots Alliance Inc  WBA.OQ , down 6.8%
    ** ServiceNow Inc  NOW.N , down 5.4%
    The top two NYSE  .PG.N  percentage gainers:
    ** AMTD Digital Inc  HKD.N , up 128%
    ** Dingdong (Cayman) Ltd  DDL.N , up 11.8%
    The top NYSE  .PL.N  percentage loser:
    ** Silvergate Capital Corp  SI.N , down 46.5%
    The top three Nasdaq  .PG.O  percentage gainers:
    ** Bellerophon Therapeutics Inc  BLPH.O , up 163.5%
    ** NovoCure Ltd  NVCR.O , up 56.7%
    ** Zai Lab Ltd  ZLAB.O , up 44.1%
    The top three Nasdaq  .PL.O  percentage losers:
    ** Cartesian Growth Corp  ALTI.O , down 21.4%
    ** Nuwellis Inc  NUWE.O , down 21%
    ** OpGen Inc  OPGN.O , down 19.6%
    ** Western Digital Corp  WDC.O : up 4.7%
    BUZZ - Rises on report of merger talks with Kioxia  urn:newsml:reuters.com:*:nL4N33Q21Y
    ** Nordstrom Inc  JWN.N : down 2.5%
    BUZZ - Falls on Piper Sandler rating cut due to earnings pressure
 urn:newsml:reuters.com:*:nL4N33Q23Z
    ** Marathon Petroleum Corp  MPC.N : up 3.7%
    BUZZ - J.P.Morgan calls Marathon Petroleum 'top-performing' refiner, raises
PT  urn:newsml:reuters.com:*:nL4N33Q262
    ** C.H. Robinson Worldwide Inc  CHRW.O : down 1.9%
    BUZZ - Cowen downgrades C.H. Robinson, sees pressure from drop in cargo
rates  urn:newsml:reuters.com:*:nL4N33Q266
    ** Boxed Inc  BOXD.N : up 14.4%
    BUZZ - Climbs on exploring strategic alternatives, including a sale
 urn:newsml:reuters.com:*:nL4N33Q2AQ
    ** Silvergate Capital Corp  SI.N : down 46.5%
    BUZZ - Hits 2-1/2 year low as crypto-related deposits plummet  urn:newsml:reuters.com:*:nL4N33Q2UI
    ** Walgreens Boots Alliance Inc  WBA.O : down 6.8%
    BUZZ - Falls on quarterly loss  urn:newsml:reuters.com:*:nL4N33Q2CY
    ** NovoCure Ltd  NVCR.O : up 56.7%
    BUZZ - Jumps as lung cancer therapy meets primary goal in study  urn:newsml:reuters.com:*:nL4N33Q2FG
    ** Conagra Brands Inc  CAG.N : up 2.6%
    BUZZ - Gains on annual forecast raise  urn:newsml:reuters.com:*:nL4N33Q27A
    ** Danaher Corp  DHR.N : down 4.2%
    BUZZ - Slips as Credit Suisse downgrades amid reduced COVID vaccine demand
 urn:newsml:reuters.com:*:nL1N33Q0U0
    ** Bed Bath & Beyond Inc  BBBY.O : down 24.1%
    BUZZ - Plummets on going concern doubts  urn:newsml:reuters.com:*:nL4N33Q2T3
    ** Y-mAbs Therapeutics Inc  YMAB.O : down 9.8%
    BUZZ - Falls as 2023 forecast for sole commercial drug disappoints
 urn:newsml:reuters.com:*:nL4N33Q2C4
    ** Orchard Therapeutics  ORTX.O : up 20.8%
    BUZZ - Jumps on FDA nod for human trials of genetic disease therapy
 urn:newsml:reuters.com:*:nL4N33Q2IY
    ** Constellation Brands Inc  STZ.N : down 6.9%
    BUZZ - Slips on earnings forecast cut  urn:newsml:reuters.com:*:nL4N33Q2VD
    ** CrowdStrike Holdings Inc  CRWD.O : down 8.1%
    BUZZ - Slides as Jefferies steps to sidelines on 'challenging' 2023
 urn:newsml:reuters.com:*:nL1N33Q0ZU
    ** Freeport-McMoRan Inc  FCX.N : up 0.8%
    BUZZ - PT raised by Raymond James on higher copper prices  urn:newsml:reuters.com:*:nL4N33Q2IR
    ** Zai Lab Ltd  ZLAB.O : up 44.1%
    BUZZ - Soars on positive data from partner's cancer therapy  urn:newsml:reuters.com:*:nL4N33Q2MU
    ** Exxon Mobil Corp  XOM.N : up 0.8% 
    ** Chevron Corp  CVX.N : up 0.4% 
    ** ConocoPhillips  COP.N : up 1.6%
    ** Occidental Petroleum Corp  OXY.N : up 1.2%
    BUZZ - Oil companies gain as U.S. pipeline shutdown lifts crude prices
 urn:newsml:reuters.com:*:nL4N33Q2KM
    ** AMTD Digital Inc  HKD.N : up 128.0%
    BUZZ - Gears up for another eye-popping rally  urn:newsml:reuters.com:*:nL4N33Q2KR
    ** Lindsay Corp  LNN.N : up 7.1%
    BUZZ - Rises on higher Q1 earnings  urn:newsml:reuters.com:*:nL4N33Q2ST
    ** ABVC BioPharma Inc  ABVC.O : up 129.0%
    BUZZ - Surges on FDA nod to start lung cancer drug trial  urn:newsml:reuters.com:*:nL4N33Q2R0
    ** Cheniere Energy Inc  LNG.N : down 0.7%
    ** Woodside Energy Group Ltd  WDS.N : down 1.1%
    ** TotalEnergies SE  TTE.N : down 0.4%
    BUZZ - Bernstein sees LNG supply remaining tight in 2023  urn:newsml:reuters.com:*:nL4N33Q2N2
    ** Tesla Inc  TSLA.O : down 5%
    BUZZ - Falls 5% on weak sales of China-made vehicles in December
 urn:newsml:reuters.com:*:nL4N33Q2UM
    ** Salarius Pharmaceuticals Inc  SLRX.O : up 7.6%
    BUZZ - Rises on U.S. patent for potential cancer therapy  urn:newsml:reuters.com:*:nL4N33Q2OR
    The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   down 1.04%
 Consumer Discretionary   .SPLRCD   down 1.11%
 Consumer Staples         .SPLRCS   down 0.79%
 Energy                   .SPNY     up 0.91%
 Financial                .SPSY     down 1.03%
 Health                   .SPXHC    down 0.99%
 Industrial               .SPLRCI   down 0.91%
 Information Technology   .SPLRCT   down 1.16%
 Materials                .SPLRCM   down 1.83%
 Real Estate              .SPLRCR   down 2.60%
 Utilities                .SPLRCU   down 2.03%
 (Compiled by Rajarshi Roy and Pratyush Thakur; Edited by Shilpi Majumdar)
 ((Rajarshi.Roy@thomsonreuters.com))

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