** Shares of AC Immune SA ACIU.O tumble 26% to $2.13
before the bell after investigational Alzheimer's treatment
fails to meet main goals in a mid-stage study
** Stock among top pct losers across all three major U.S.
stock indexes
** Says crenezumab did not "statistically significantly"
slow or prevent cognitive decline in people with a specific
genetic mutation that causes early-onset of Alzheimer's
urn:newsml:reuters.com:*:nGNX64TycL
** Adds crenezumab's safety profile and favorable numerical
differences observed against placebo in study require further
analyses
** Up to Wednesday's close, ACIU down 42% YTD
(Reporting by Bhanvi Satija in Bengaluru)
((Bhanvi.Satija@thomsonreuters.com; Outside U.S. +91
9873062788;))