** Shares of biotech firm Alpine Immune Sciences ALPN.O
surge 36.1% to $64 premarket, as Vertex Pharma VRTX.O set to
buy co for $4.9 bln
** Stock just shy of Vertex's offer price of $65/shr, which
represents a 67% premium to ALPN's Tuesday close, a day before
Bloomberg reported that it had received a takeover interest
** Vertex will gain access to ALPN's treatment for an
autoimmune disease of the kidney known as IgA nephropathy, which
affects about 130,000 people in the United States
** VRTX down 2% premarket
** APLN up nearly 147% YTD as of last close, while VRTX is
down 2.3%
(Reporting by Pranav Kashyap in Bengaluru)
((Pranav.Kashyap@thomsonreuters.com;))