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REG - Aptamer Group PLC - Interim Results and Notice of Investor Webinar

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RNS Number : 0113Y  Aptamer Group PLC  25 March 2026

 

25 March 2026

Aptamer Group plc

 

("Aptamer", the "Company" or the "Group")

 

Interim results for the six months ended 31 December 2025

 

Revenue growth, solid cash position and strong technical progress

 

Notice of investor webinar

 

Aptamer Group plc (AIM: APTA), the developer of next-generation synthetic
binders for the life sciences industry, today announces its unaudited interim
results for the six months ended 31 December 2025 (H1 2026).

 

Financial highlights

·      Revenue £0.83 million (H1 2025: £0.65 million), a 27%
increase reflecting continued commercial traction

·      Adjusted EBITDA loss reduced to £1.0 million (H1 2025:
£1.1 million)

·      Successful fundraising in July 2025 of £1.8 million (net of
costs)

·      Cash balance at 31 December 2025 of £1.5 million (H1 2025:
£2.0 million) giving a cash runway that extends through to Q2 2027 on the
expected trajectory

 

Strategic programme advances

·    Enzyme-modulating Optimers out-licensed to Twist Bioscience and
Alphazyme. Licensing terms include an upfront payment, royalties and supply
revenue

·    Second enzyme-modulating discovery project with Alphazyme completed;
high-performance binders selected and licensing heads of terms agreed

·    Third global enzyme manufacturer evaluating enzyme-modulating
Optimer® binders under a Material Transfer Agreement

·    Optimer® immunohistochemistry (IHC) reagents successfully developed
for an established global life sciences and diagnostics conglomerate.
Potential to be integrated into assay kits this year, with agreed royalties of
2% on net sales of all products

·    Manufacturing capacity increased and quality systems audited to
support supply of licensed assets

·    Fibrotic liver delivery vehicle demonstrated excellent preclinical
characteristics, being non-toxic, stable and non-immunogenic, significantly
de-risking its therapeutic potential

·    Unilever programmes advancing through development stages: stability
assessment work on the first deodorant programme successfully completed and
delivered, supporting the current on-skin testing phase; second programme has
shown positive internal results and is approaching delivery for customer
evaluation

 

Fee-for-service contracts

·    First contract win in the radioligand therapy market secured with a
top 3 global pharmaceutical partner, totalling £360,000, marking a
significant strategic entry into this high-value, high-growth sector

·    £769,000 in new contracts secured from a single top 5 pharmaceutical
partner, with total contract value exceeding £1 million with this partner

·    Repeat business secured with a top 10 pharmaceutical company and a
top 20 pharmaceutical company to support research activities with targets
intractable for other technologies

·    Therapeutic development agreement with Invizius in September 2025

·    Agreement signed with Metir plc for Optimer® development targeting
detection of Cryptosporidium in water and environmental testing in September
2025

 

Post-period developments

·    Launch of Optimer®-containing kits from Twist and Alphazyme with
first licensing payments received

·    Licensing discussions nearing completion with Alphazyme for the
second hot start PCR Optimer®

·    Radioligand therapy programme initiated in partnership with
Radiopharmium, with preclinical results anticipated by the end of 2026

·    Successful launch of an Accelerated Book Build on 25 March 2026,
which will generate proceeds of at least £3.75 million. These proceeds will
provide the necessary capital required for the Company to advance new and
existing asset development programmes and provide a cash runway through to
2028

 

Commenting on the interim results, Dr Arron Tolley, Chief Executive
Officer of Aptamer Group, said:

 

"The first half of the financial year has seen Aptamer make meaningful
progress across all three pillars of its strategy: fee‑for‑service, asset
development and licensing. The Group's Optimer® platform is now generating
its first product‑linked revenues through partners such as Twist Bioscience
and Alphazyme, while Unilever programmes and the fibrotic liver delivery
vehicle continue to advance through preclinical and development stages.

 

Aptamer's partnership with Unilever is progressing well, and the Group's
fibrotic liver delivery vehicle has shown strong preclinical results. In
parallel, we continue to progress our asset portfolio with industrial
partners, with several other assets being evaluated under a Material Transfer
Agreement. Our Optimer® fee‑for‑service activity continues to solve
intractable problems for pharma partners, generating significant repeat
contracts from multiple global pharmaceutical companies. We also announced our
first contract win in the high‑value, high‑growth radioligand therapy
market, based on the potential strength of Optimers as delivery vehicles for
this exciting class of new therapeutic modalities. These paid development
programmes are creating licensable assets in their own right, reinforcing the
pathway from discovery work to long‑term passive income.

 

Following today's Accelerated Book Build launch announcement to raise
additional growth capital, we are delighted that new and existing shareholders
have recognised the opportunities ahead for Aptamer. This investment will
allow us to develop new proprietary assets, creating further value for
shareholders, while funding the development of our AI‑enhanced
fee‑for‑service offering and the systematic exploration of undruggable and
undeliverable targets using our novel oligonucleotide‑based platform. The
Group look forward to generating the in vivo data needed to validate our
therapeutic programmes and to positioning Aptamer as a credible player in this
expanding market."

 

Investor webinar

Dr Arron Tolley (Chief Executive Officer) and Andrew Rapson (Chief Financial
Officer) will provide a live presentation relating to the Interim Results via
Investor Meet Company on Monday, 30 March 2026, 14:00 GMT.

 

The live presentation is open to all existing and potential shareholders.
Questions can be submitted at any time during the live presentation.

 

Investors can sign up to Investor Meet Company for free and add to meet
Aptamer Group plc via:

https://www.investormeetcompany.com/aptamer-group-plc/register-investor
(https://www.investormeetcompany.com/aptamer-group-plc/register-investor)

 

Investors who already follow Aptamer Group Plc on the Investor Meet Company
platform will automatically be invited.

 

- Ends -

 

For further information, please contact:

 

 Aptamer Group plc                                               +44 (0) 1904 217 404 

 Dr Arron Tolley, Chief Executive Officer
 SPARK Advisory Partners Limited - Nominated Adviser             +44 (0) 20 3368 3550 

 Andrew Emmott / Dillon Wall
 Turner Pope Investments (TPI) Limited - Broker                  +44 (0) 20 3657 0050 

 Andrew Thacker / Guy McDougall
 Northstar Communications Limited - Investor Relations           +44 (0) 113 730 3896

 Sarah Hollins

 

About Aptamer Group

 

Aptamer Group is a leading developer of next-generation synthetic binders
delivering innovation to the life sciences industry. The Group develops
Optimer® binders, advanced molecules that work like antibodies by attaching
to specific targets in the body. These binders are used in medicine,
diagnostic tests, and research tools, offering benefits like high stability,
reliable performance, and lower costs compared to traditional antibodies.

 

Aptamer operates a fee-for-service business in the US$210 billion market for
antibody alternatives, working with all top 10 global pharmaceutical
companies. It is also building valuable Optimer® assets with partners, aiming
for future licensing revenue.

 

Founded in 2008, the Group listed on the London Stock Exchange AIM market in
December 2021 and is headquartered in York, UK.

 

To register for news alerts by email go to
https://aptamergroup.com/investors/investor-news-email-alerts/
(https://aptamergroup.com/investors/investor-news-email-alerts/)

 

Chairman and Chief Executive Officer's statement

 

Aptamer is pleased to report a strong first half, marked by 27% revenue
growth, significant progress across the Group's licensable asset portfolio
with multiple licensing agreements signed, and growing commercial momentum
with world-leading partners. The period has reinforced the Group's confidence
in its strategic direction and its ability to deliver on its vision of
building a sustainable, royalty-driven business.

 

Growing revenue and expanding partnerships

 

Revenue grew to £0.83 million (H1 2025: £0.65 million), as the Group
continued to grow its blue-chip customer base across pharmaceutical,
diagnostic, and consumer goods sectors.

 

This growth has again been driven by deepening relationships with major
partners, with £769,000 in total contract value secured from a single top 5
pharmaceutical partner, alongside further repeat business with multiple top 20
pharmaceutical companies. Early feedback from this work has confirmed that the
Group's Optimers outperformed all antibodies tested under customer-relevant
conditions, reinforcing the technical advantages of Aptamer's platform to
deliver on targets that prove intractable with alternative modalities and the
strength of the Group's commercial relationships.

 

A particularly significant milestone in this period was Aptamer's entry into
the radioligand therapy market, securing a development contract with a top 3
global pharmaceutical company to engineer Optimer® binders as targeted
radiopharmaceuticals for cancer imaging and potential therapeutic
applications. This represents the Group's second therapeutic modality under
active development alongside targeted gene therapy and positions Aptamer for
meaningful downstream licensing revenues as this high-growth market continues
to expand.

 

Advancing our licensable asset portfolio

 

Aptamer's primary strategic objective remains to develop a diversified
portfolio of proprietary Optimer® assets capable of generating long-term
royalty and licensing revenues. The Group has made substantial progress
towards this goal during the period.

 

Progress in the Group's partnership with Unilever continues, following the
successful completion of stability assessments within the first Optimer®
programme. The second programme, targeting an additional odour-prevention
pathway, has delivered positive internal results and is approaching delivery
to Unilever for evaluation. Together, these programmes represent a significant
licensing opportunity in the large and growing cosmetics market.

 

The fibrotic liver delivery vehicle programme has cleared a critical hurdle,
with lab-based testing demonstrating excellent preclinical characteristics of
being non-toxic, stable and non-immunogenic. These results significantly
de-risk the asset's therapeutic potential and support the Group's ongoing
discussions with pharmaceutical partners regarding high-value licensing
opportunities. Animal studies are anticipated to begin in this financial year
to demonstrate targeting performance and safety for this potentially
high-value therapeutic asset. The Group continue to see applications for this
platform across multiple fibrotic diseases, substantially expanding the
addressable market.

 

As part of Aptamer's partnership with a global life sciences and diagnostics
conglomerate, the Optimer® immunohistochemistry reagents have been
successfully developed and are being prepared for shipment to the customer.
With 2% royalties agreed on net sales and potential integration into
commercial assay kits this year, this asset is approaching the point of
generating passive income for the Group, further demonstrating Aptamer's
strategy in action.

 

The Group's enzyme-modulating Optimer® assets have reached commercialisation
milestones. These Optimers have been out-licensed to Twist Bioscience and
Alphazyme, with both products now launched in the market and first licensing
payments received post-period. A second discovery project with Alphazyme has
been completed, and the customer has selected and validated high-performance
binders. Licensing discussions for this second hot-start PCR Optimer are
anticipated to be completed within the current financial year. A third global
enzyme manufacturer is also evaluating the Group's hot-start PCR Optimer under
a Material Transfer Agreement, with potential for further licensing.

 

A critical enabler of the Group's licensing strategy is its ability to
reliably supply licensable assets. During this period, Aptamer has invested in
manufacturing processes and completed quality audits to ensure the Group's
operations meet the standards required by its global partners. This investment
underpins the Group's ability to fulfil supply obligations under existing and
future licensing agreements, improves margins through in-house production and
simplifies partner logistics. As Aptamer's licensed asset portfolio grows,
this manufacturing capability will become an increasingly important value
driver.

 

Beyond Aptamer's existing programmes, the period has also seen the Group lay
the foundations for a novel class of licensable artificial intelligence (AI)
assets. During the period, the Group made a key hire of an expert in machine
learning and protein-RNA interaction modelling, who will lead the development
of Aptamer's AI programme.

 

Whilst AI-assisted approaches to molecular discovery are becoming increasingly
common across the life sciences industry, Aptamer is uniquely positioned to
capitalise on this trend through its extensive proprietary data libraries,
accumulated over more than 15 years of discovery work. These libraries provide
a robust, high-quality training foundation for developing predictive AI
models, giving the Group a strong starting position compared with competitors
in the space that lack this depth of underlying data.

 

In the near term, the Group expects these models to accelerate Aptamer's
discovery programmes, improving the prediction of optimal sequences and
enhancing the quality of assets entering the Group's licensing portfolio.
Looking further ahead, Aptamer sees potential to offer these AI models as
licensable assets, creating an additional long-term revenue stream for the
Group.

 

Post-period developments

 

Commercial momentum has continued into the second half. The launch of
Optimer®-containing products by Twist Bioscience and Alphazyme, with the
first licensing payments received, marks the Group's transition towards
recurring passive income. Additional fee-for-service contracts have been
secured with new and existing partners, further strengthening the Group's
revenue pipeline.

 

The Group has also launched an internal targeted radiopharmaceutical
development programme, with three therapeutic targets identified and discovery
initiated within Aptamer, bringing the total radiotherapy pipeline to four
assets, with in vivo data targeted by the end of 2026. The manufacturing and
preclinical aspects of this programme will be managed by Dr Louis Allot, a
recognised expert in radiopharmaceutical development and a member of Aptamer's
Scientific Advisory Board.

 

On 25 March 2026, the Group announced the launch of an Accelerated Book Build
which will raise a minimum of £3.75 million (gross). The proceeds from this
fundraise will be used to advance the Group's R&D development programmes
and provide a cash runway through to 2028.

 

Outlook

 

Aptamer enters the second half of the financial year with a solid cash
position, an expanding portfolio of licensable assets at various stages of
commercialisation and a robust pipeline of fee-for-service engagements with
global pharmaceutical and diagnostic leaders. The Group's strategic priorities
remain clear: to convert Aptamer's growing asset portfolio into recurring
royalty and licensing revenues, to deepen relationships with world-leading
partners and to maintain the cost discipline that underpins the Group's path
to sustainable profitability.

 

The first half of the financial year has seen Aptamer transition from a
business building towards licensing revenues to one beginning to receive them.
With products in the market, royalty agreements signed, a pipeline spanning
cosmetics, diagnostics, therapeutics and research reagents, and a nascent
radiopharmaceutical pipeline now taking shape, the Group is confident in its
ability to deliver sustainable long-term value to shareholders.

 

Financial review

 

Revenue

 

Revenue for the six months ended 31 December 2025 was £0.83 million (H1 2024:
£0.65 million) as the Group closed some key fee-for-service contracts with
top 5 pharma companies in the financial period.  The Group has seen improved
interest and repeat business from top pharma companies on the back of
successful projects delivered to these customers in the prior period.

 

At the end of the period, the Group still had £1.2 million of signed orders
that were progressing through the laboratory, most of which is expected to be
recognised in the second half of the financial year, subject to scientific
attrition. The pipeline at the period end stood at £3.1 million, which the
Group will be looking to convert a portion of during the second half of the
financial year.

 

Gross profit

 

Gross profit for the first half of the financial year was £0.5 million (H1
2025: £0.4 million), representing a 56% gross profit margin, comparable with
the 56% gross profit margin in the prior period.

 

Administrative expenses

 

Administrative expenses were £1.5 million for the first six months of the
year compared with £1.5 million for the same period last year. The Group has
looked to maintain a lean cost base and limit increases where possible.  The
headcount reduced slightly from 31 at 30 June 2025 to 30 at 31 December 2025.

 

Research and development costs

 

During the first half of the financial year, the Group expensed £0.2 million
(H1 2024: £0.2 million) within Administrative Expenses on research and
development costs (employee costs and raw materials), bringing the fibrotic
liver delivery programme through to a point where it is ready to go into
animal studies.

 

Adjusted EBITDA*

 

Adjusted EBITDA was a loss of £1.0 million for the six months ended 31
December 2025 (H1 2025: £1.1 million). The decrease in loss was a result of
improved revenue whilst maintaining a lean administrative cost base.

 

*Adjusted EBITDA is defined as Operating Loss before Share-based payment
expense, Amortisation and Depreciation and a reconciliation to Operating Loss
is shown within the Consolidated Statement of Profit and Loss and
Comprehensive Income.

 

Tax

 

The Group claims research and development ("R&D") tax credits. Since it is
loss making, the Group elects to surrender these tax credits for a cash
rebate. The benefit to the Group is included within the taxation line of the
income statement and amounts to £0.1 million for the first half of the year.
Within current assets is a corporation tax debtor of £0.2 million, which
relates to anticipated R&D tax credits in respect of claims not yet
received/submitted for the 2025 and 2026 financial years.

 

The claim for the year to 30 June 2025 amounted to £0.15 million and was
received in February 2026. Tax losses carried forward totalled £13.6 million
(June 2025: £13.5 million). The Group has not recognised any deferred tax
assets in respect of trading losses arising in the current period or
accumulated losses in previous periods.

 

Loss for the period

 

The loss for the period was £1.1 million (H1 2025: £1.1 million). The basic
and diluted loss per ordinary share decreased to 0.04 pence per share (H1
2025: 0.07 pence per share) based upon an average number of shares in issue
during the period of 2,632,004,802 (H1 2025: 1,583,220,709).

 

Cash flow

 

The Group had £1.5 million of cash at 31 December 2025 (H1 2025: £2.0
million, FY25: £1.0 million). The cash inflow for the six-month period to 31
December 2025 was £0.5 million. During the period, proceeds of £1.8 million,
net of costs, were received from placings and £0.1 million was received from
the exercise of warrants. Net cash used in operations totalled £1.2 million,
which is slightly higher than the Adjusted EBITDA loss of £1.0 million due to
a build-up of trade debtors at the period end, most of which have been cleared
in January and February 2026.

 

Going concern

 

For the reasons set out in note 3, the Directors believe that it remains
appropriate to prepare the financial statements on a going concern basis.

 

CONSOLIDATED STATEMENT OF PROFIT AND LOSS AND COMPREHENSIVE INCOME

For the six-month period ended 31 December 2025

 

                                                                                                                                               Unaudited                         Unaudited                  Audited

                                                                                                                                               6 months ended 31 December 2025   6 months                   year

                                                                                                                                                                                  ended 31 December 2024    ended

                                                                                                                                                                                                            30 June

                                                                                                                                                                                                            2025
                                                                                                                                   Note  £'000                                   £'000                      £'000
 Revenue                                                                                                                           4     828                                     653                        1,203
 Cost of sales                                                                                                                           (368)                                   (286)                      (624)
 Gross profit                                                                                                                            460                                     367                        579
 Administrative expenses                                                                                                                 (1,524)                                 (1,519)                    (2,931)
 Other operating income                                                                                                                  45                                      79                         158
 Adjusted EBITDA                                                                                                                         (1,019)                                 (1,073)                    (2,194)
 Depreciation (including loss on disposal)                                                                                               (108)                                   (104)                      (207)
 Amortisation of intangible assets                                                                                                       (12)                                    (11)                       (22)
 Share-based payment expense                                                                                                             (99)                                    6                          (116)
 Operating loss                                                                                                                    5     (1,238)                                 (1,182)                    (2,539)
 Finance income                                                                                                                          19                                      13                         27
 Finance costs                                                                                                                           (19)                                    (31)                       (57)
 Loss before taxation                                                                                                                    (1,238)                                 (1,200)                    (2,569)
 Taxation                                                                                                                          6     90                                      88                         145
 Loss and total comprehensive expense for the                                                                                            (1,148)                                 (1,112)                    (2,424)
 period/year

 Basic loss per share                                                                                                              7     0.04p                                   0.07p                      0.14p
 Diluted loss per share                                                                                                            7     0.04p                                   0.07p                      0.14p

 

CONSOLIDATED STATEMENT OF FINANCIAL POSITION

At 31 December 2025

                                                  Unaudited     Unaudited     Audited

                                                  31 December   31 December   30 June

                                                  2025          2024           2025

                                           Note   £'000         £'000         £'000
 Assets
 Non-current
 Other intangible assets                          247           183           225
 Property, plant, and equipment            8      225           358           290
 Right-of-use assets                              93            154           124
 Other receivables                                373           373           373
                                                  938           1,068         1,012
 Current
 Inventories                                      67            107           80
 Trade and other receivables               9      959           924           534
 Tax receivable                                   239           280           149
 Cash and cash equivalents                        1,528         1,967         1,059
                                                  2,793         3,278         1,822
 Total assets                                     3,731         4,346         2,834
 Current liabilities
 Trade and other payables                  10     (1,110)       (1,104)       (926)
 Borrowings                                       (4)           (10)          (9)
 Leases                                           (253)         (228)         (240)
                                                  (1,367)       (1,342)       (1,175)
 Net current assets                               1,426         1,936         647
 Non-current liabilities
 Trade and other payables                         -             (2)           -
 Borrowings                                       -             (4)           -
 Leases                                           (76)          (401)         (242)
 Provisions for liabilities                       (35)          (35)          (35)
                                                  (111)         (442)         (277)
 Net assets                                       2,253         2,562         1,382

 Equity
 Issued share capital                             2,697         1,988         1,991
 Share premium                                    14,659        13,944        13,634
 Group reorganisation reserve                     185           185           185
 Share based payments reserve                     840           468           619
 Accumulated losses                               (16,128)      (14,023)      (15,047)
 Equity attributable to shareholders              2,253         2,562         1,382

 

CONSOLIDATED STATEMENT OF CHANGES IN EQUITY

For the six-month period ended 31 December 2025

                                                                                             Issued share  Share premium  Group reorganisation reserve      Share-based payment reserve  Retained earnings     Total equity

                                                                                             capital
                                                                                             £'000         £'000          £'000            £'000                                                    £'000               £'000
      At 1 July 2024 (audited)                                                               467           12,672         185              504                                                      (12,941)            887

      Loss for the period                                                                    -             -              -                -                                                        (1,112)             (1,112)
      Issue of share capital                                                                 1,453         1,453          -                -                                                        -                   2,906
      Share issue costs                                                                                    (312)                                                                                                        (312)
      Shares issued in lieu of cash                                                          68            131            -                -                                                        -                   199
      Share based payments                                                                   -             -              -                (6)                                                      -                   (6)
      Exercise & forfeited equity-settled share-based payments                               -             -              -                (30)                                                     30                  -
      Total transactions with owners, recognised directly in equity                          1,521         1,272          -                (36)                                                     30                  2,787

      At 31 December 2024 (unaudited)                                                        1,988         13,944         185              468                                                      (14,023)            2,562

      Loss for the period                                                                    -             -              -                -                                                        (1,312)             (1,312)
      Issue of share capital                                                                 -             -              -                -                                                        -                   -
      Issue of broker warrants                                                               -             (317)          -                317                                                      -                   -
      Share based payments                                                                   3             7              -                106                                                      -                   116
      Exercise & forfeited equity-settled share-based payments                               -             -              -                (272)                                                    288                 16
      Total transactions with owners, recognised directly in equity                          3             (310)          -                151                                                      288                 132

      At 30 June 2025 (audited)                                                              1,991         13,634         185              619                                                      (15,047)            1,382

      Loss for the period                                                                    -             -              -                -                                                        (1,148)             (1,148)
      Issue of share capital                                                                 703           1,380          -                -                                                        -                   2,083
      Share issue costs                                                                      -             (172)          -                -                                                        -                   (172)
      Share-based payments                                                                   3             6              -                99                                                       -                   108
      Exercise of broker warrants                                                            -             -              -                (65)                                                     65                  -
      Issue of broker warrants                                                               -             (189)          -                189                                                      -                   -
      Exercise & forfeited equity-settled share-based payments                               -             -              -                (2)                                                      2                   -
      Total transactions with owners, recognised directly in equity                          706           1,025          -                221                                                      67                  2,019

      At 31 December 2025 (unaudited)                                                        2,697         14,659         185              840                                                      (16,128)            2,253
      On 4 July 2025, the Directors announced a significant new fundraising event

    which resulted in a firm placing of 400,419,909 ordinary shares for total
      proceeds of £1.2 million and a conditional placing of 266,246,757 ordinary

    shares for total proceeds of £0.8 million. The conditional placing was
      approved at a General Meeting on 24 July 2025, and total net proceeds were

    £1.8 million.

    On 19 August 2025, 36,000,000 broker warrants were exercised, and the company
      received proceeds of £0.07 million.

CONSOLIDATED STATEMENT OF CASH FLOWS

For the six-month period ended 31 December 2025

 

                                                                                              Unaudited

                                                            Unaudited                         6 months ended 31 December 2024   Audited

                                                            6 months ended 31 December 2025   £'000                             year

                                                            £'000                                                               ended 30 June

                                                                                                                                2025

                                                                                                                                £'000

 Cash flows from operating activities
 Loss for the period/year                                   (1,148)                           (1,112)                           (2,424)
 Adjustments for:
 Taxation                                                   (90)                              (88)                              (145)
 Finance costs                                              19                                31                                30
 Amortisation                                               12                                11                                22
 Depreciation                                               108                               104                               207
 Fees paid in shares in lieu of cash                        10                                111                               196
 Share-based payment expense                                99                                (6)                               116
 Operating cash outflow before changes in working capital   (990)                             (949)                             (1,997)
 Decrease in inventory                                      13                                13                                40
 (Increase) in debtors                                      (425)                             (426)                             (95)
 Decrease/(increase) in creditors                           193                               74                                (107)
 Cash outflow from operations                               (1,209)                           (1,288)                           (2,159)
 Income taxes received                                      -                                 -                                 215
 Net cash used in operating activities                      (1,209)                           (1,288)                           (1,944)

 Cash flows from investing activities
 Purchase of property, plant, and equipment                 (10)                              (6)                               (10)
 Purchase of intangible assets                              (34)                              (28)                              (82)
 Net cash used in investing activities                      (44)                              (34)                              (92)

 Cash flows from financing activities
 Issue of share capital, net of issue costs                 1,901                             2,623                             2,608
 Proceeds from borrowings                                   -                                 -                                 -
 Repayment of borrowings                                    (5)                               (33)                              (38)
 Payment of lease liabilities                               (153)                             (140)                             (288)
 Interest paid                                              (21)                              (31)                              (57)
 Net cash generated from financing activities               1,722                             2,419                             2,225

 Net increase in cash and cash equivalents                  469                               1,097                             189

 Cash and cash equivalents at beginning of the period/year  1,059                             870                               870
 Cash and cash equivalents at end of the period/year        1,528                             1,967                             1,059

NOTES TO THE FINANCIAL STATEMENTS

For the six-month period ended 31 December 2025

 

1.    GENERAL INFORMATION

Aptamer Group plc ('the Company') is a public limited company domiciled and
incorporated in England and Wales. These interim consolidated financial
statements of the Company for the six-month period ended 31 December 2025
comprise the Company and its subsidiaries (together referred to as 'the
Group').

 

The address of the Company's registered office is Windmill House, Innovation
Way, Heslington, York, YO10 5BR.

 

This interim report was authorised for issue in accordance with a resolution
of the Directors on 25 March 2026.

 

2.    BASIS OF PREPARATION

The results for the 6-month periods to 31 December 2025 and 31 December 2024
are unaudited. The disclosed figures are not statutory accounts in terms of
Section 435 of the Companies Act 2006. Statutory accounts for the year ended
30 June 2025 on which the auditors gave an audit report which was unqualified,
have been filed with the Registrar of Companies. The auditor has reported on
those accounts; their report was unqualified and did not contain a statement
under Section 498(2) or (3) of the Companies Act 2006; though it did include a
reference to a matter to which the auditor drew attention by way of emphasis
without qualifying their report in relation to going concern. The annual
financial statements of the Group are prepared in accordance with UK adopted
International Financial Reporting Standards (IFRS) and, as regards the Company
financial statements, as applied in accordance with the provisions of the
Companies Act 2006.

 

This interim report has been prepared on a basis consistent with the
accounting policies expected to be applied for the year ending 30 June 2026,
and uses the same accounting policies and methods of computation applied for
the year ended 30 June 2025.

 

3.    GOING CONCERN

The Group has reported a loss after tax for the six months ended 31 December
2025 of £1.1 million (six months ended 31 December 2024: £1.1 million).
The Group had a cash balance of £1.5 million at 31 December 2025 (31 December
2024: £2.0 million).  On 25 March 2026, the Group announced the launch of an
Accelerated Book Build (ABB) which is expected to generate gross proceeds of
at least £3.75 million, of which £0.75 million will be allocated to working
capital.

 

The Directors have considered the suitability of the going concern basis in
the preparation of these interim results, which includes assessing an internal
forecast extending out to June 2027.  The Directors consider that this
forecast represents a reasonable best estimate of the performance of the Group
over the period to June 2027.  In the forecast, revenue is forecast to grow
based the Group starting the generate licensing revenue from two licenses
signed in December 2025. Should these sales materialise, combined with the
proceeds received from the ABB launched on 25 March 2026, then the cash runway
extends more than 12 months from the date of these interim results.

 

Based on the above factors, the Directors believe that it remains appropriate
to prepare the interim results on a going concern basis.

 

4.    REVENUE

An analysis of revenue, all of which relates to the sale of services, by
geographical location of the customer is given below:

                    6 months ended 31 December 2025  6 months ended 31 December 2024  Year ended 30 June 2025

                    £'000                            £'000                            £'000

 United Kingdom     150                              168                              235
 Europe             18                               101                              239
 Rest of the World  660                              384                              729
                    828                              653                              1,203

All assets are located in, and services delivered from, the United Kingdom.

 

5.    OPERATING LOSS

The operating loss for the period/year is stated after charging:

                                                                                                           Year ended 30 June 2025

                                                 6 months ended 31 December   6 months ended 31 December

                                                  2025                         2024
                                                 £'000                        £'000                        £'000
 Employee remuneration                           1,040                        964                          1,930
 Share-based payments                            99                           (6)                          116
 Research and development raw materials          127                          120                          305
 Depreciation of property, plant, and equipment  77                           72                           144
 Depreciation of right-of-use assets             31                           32                           63
 Amortisation of intangible assets               12                           11                           22
 Raw materials and consumables used              144                          89                           156

 
6.    TAXATION

The Group's tax credit for the six months ended 31 December 2025 was £90,000
(six months ended 31 December 2024: £88,000; year ended 30 June 2025:
£145,000).

 

Within debtors is a corporation tax debtor of £239,000. This includes an
anticipated R&D tax credit in respect of claims not yet submitted for the
2026 financial year, and to a submitted claim for the year to 30 June 2025 of
£152,000.

 

At 31 December 2025, the Group had unrelieved tax losses of approximately
£13,588,000 (30 June 2025 - £13,503,000). A deferred tax asset has not been
recognised in respect of these losses, except for losses recognised against
deferred tax liabilities against which the losses will automatically unwind
(and which are accordingly offset).

 

 

7.    LOSS PER SHARE
                                                            6 months            6 months  ended 31 December 2024

                                                            ended 31 December                                      Year ended 30 June 2025

                                                            2025
 Basic loss per share                                       0.04p               0.07p                              0.14p
 Diluted loss per share                                     0.04p               0.07p                              0.14p
 Loss for the period/year                                   £1,148,000          £1,112,000                         £2,424,000
 Weighted average number of ordinary shares used            2,632,004,802       1,583,220,709                      1,883,309,991

 as the denominator in calculating the basic/diluted loss

 per share

8.    PROPERTY, PLANT AND EQUIPMENT
                                  Leasehold improvements  Other property, plant and equipment

                                  £'000                   £'000                                Fixtures, fittings and equipment

                                                                                               £'000

                                                                                                                                  Total

                                                                                                                                  £'000
 Cost
 At 1 July 2024                   1,607                   1,465                                36                                 3,108
 Additions                        -                       6                                    4                                  10
 Transfers                        -                       210                                  -                                  210
 At 30 June 2025 (audited)        1,607                   1,681                                40                                 3,328
 Additions                        -                       6                                    6                                  12
 At 31 December 2025 (unaudited)  1,607                   1,687                                46                                 3,340

 Accumulated depreciation
 At 1 July 2024                   1,357                   1,299                                28                                 2,684
 Charge for the year              97                      43                                   4                                  144
 Transfers                        -                       210                                  -                                  210
 At 30 June 2025 (audited)        1,454                   1,552                                32                                 3,038
 Charge for the period            48                      27                                   2                                  77
 At 31 December 2025 (unaudited)  1,502                   1,579                                34                                 3,115

 Net book values
 31 December 2025 (unaudited)     105                     108                                  12                                 225
 30 June 2025 (audited)           153                     129                                  8                                  290

 
9.    TRADE AND OTHER RECEIVABLES
                    31 December  31 December  30 June

                     2025         2024         2025
                    £'000        £'000        £'000
 Trade receivables  731          657          342
 Other receivables  80           53           41
 Prepayments        148          214          151
                    959          924          534

 

10.  CURRENT LIABILITIES
                                     31 December  31 December  30 June

                                      2025        2024          2025
                                     £'000        £'000        £'000
 Trade payables                      593          466          414
 Other taxation and social security  56           53           58
 Other payables                      105          -            105
 Accruals                            267          312          292
 Deferred income                     87           273          57
                                     1,108        1,104        926

 

Inside Information

This announcement contains inside information for the purposes of the UK
Market Abuse Regulations ('UK MAR'). Upon publication of this announcement,
this inside information (as defined in UK MAR) is now considered to be in the
public domain. The person responsible for arranging the release of this
announcement on behalf of the Company is Dr Arron Tolley, Chief Executive
Officer.

 

 

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