** Aptinyx Inc's shares APTX.O fall 35% to 39 cents -
among the biggest pct losers across all U.S. stock exchanges
premarket
** APTX experimental drug to treat chronic pain did not meet
the main goal of a mid-stage study urn:newsml:reuters.com:*:nBw4htMcja
** The drug, NYX-2925, when compared to placebo was not
statistically significant in reducing pain in patients with
fibromyalgia, a disorder that causes muscular pain
** Stock has fallen nearly 50% since early April, when
NYX-2925 failed to meet the main goal of a separate trial
testing it in patients with nerve pain urn:newsml:reuters.com:*:nL3N2W52F6
** Up to Thursday's close, stock was down ~78% YTD
(Reporting by Khushi Mandowara)
((Khushi.Mandowara@thomsonreuters.com;))