** Drug developer's shares APTX.O fall 5% premarket to a
record low of $1.13, set to extend declines of ~50% from
Thursday after its nerve pain drug failed to meet goals in a
mid-stage study urn:newsml:reuters.com:*:nL3N2W5345
** William Blair downgrades stock to "market perform", at
least two brokerages cut PT
** The failure adds risk to co's Fibromyalgia trial -
William Blair
** "We are humbly reminded of hazards of relying on post-hoc
data and remove NYX-2925 from our valuation" - Truist, more than
halves PT to $5
** Median PT is $6 - Refinitiv data
** Shares set to extend losses to a fourth straight session;
down 55% YTD
(Reporting by Susan Mathew)
((susan.mathew@thomsonreuters.com))