** U.S.-listed shares of drug developer Aptose Biosciences
APTO.O APS.TO rise 21.57% to 31 cents
** Co says its first line combination treatment is safe and
tolerable in patients with a type of blood cancer in an
early-stage trial
** Co is testing its experimental drug tuspetinib in
combination with two other standard of care therapies
** To date, four patients have received lowest dose (40 mg)
of the combination treatment
** The once daily therapy is being developed to treat newly
diagnosed patients with a type of blood cancer who are
ineligible to receive induction chemotherapy
** Expects enrollment of 18-24 patients by mid-late 2025
** In the last 12 months, the stock down 87.5%
(Reporting by Siddhi Mahatole)
((Siddhiprabhanjan.mahatole@thomsonreuters.com))