** Shares of cancer-focused cell therapy developer Arcellx
ACLX.O up 12.7% at $53.5 premarket
** ACLX and Kite, unit of Gilead Sciences' GILD.O , report
expansion of existing collaboration, originally announced in Dec
last year
** Upon closing, ACLX to receive $200 mln in equity
investment at $61.68/share and also $85 mln upfront cash payment
** Kite has exercised its option to negotiate license for
ACLX's experimental therapy ACLX-001 in treating type of blood
cancer, multiple myeloma
** Companies have also expanded the collaboration scope for
Arcellx's lead product candidate for cancer immunotherapy,
CART-ddBCMA, which is being co-developed with Kite, to include
lymphomas
** CART-ddBCMA is currently in pivotal mid-stage trial for
multiple myeloma
** Assuming transaction closes around year-end 2023,
Gilead's 2023 adj. per share earnings is expected to reduce by
about $0.09-$0.11/share
** Up to Tuesday's close, ACLX up ~53% YTD
(Reporting by Pratik Jain in Bengaluru)
((Pratik.Jain@thomsonreuters.com;))