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U.S. STOCKS ON THE MOVE-Annovis Bio, Hoth Therapeutics, Digital Realty

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Wall Street's main indexes slipped on Tuesday, weighed down by technology stocks after a batch
of upbeat economic data stoked uncertainty among investors about the pace of monetary policy
easing that the Federal Reserve could pursue this year.  .N 
   
At 13:30 EST, the Dow Jones Industrial Average  .DJI  was down 0.02% at 42,698.70.The S&P 500
 .SPX  was down 0.52% at 5,944.08 and the Nasdaq Composite  .IXIC  was down 1.17% at 19,632.48.
The top three S&P 500  .PG.INX  percentage gainers:
** Moderna Inc  MRNA.OQ , up 14.0%
** Enphase Energy Inc  ENPH.OQ , up 7.5%
** Texas Pacific Land Corp  TPL.N , up 5.0%
The top three S&P 500  .PL.INX  percentage losers:
** Palantir Technologies Inc  PLTR.OQ , down 6.4%
** NVIDIA Corp  NVDA.OQ , down 4.3%
** Take-Two Interactive Software Inc  TTWO.OQ , down 3.7%
 
The top three NYSE  .PG.N  percentage gainers:
** Getty Images Holdings Inc  GETY.N , up 24.1%
** UniFirst Corp  UNF.N , up 21.1%
** Shutterstock Inc  SSTK.N , up 19.6%
The top three NYSE  .PL.N  percentage losers:
** BP Prudhoe Bay Royalty Trust  BPT.N , down 30.4%
** Kuke Music Holding Ltd  KUKE.N , down 20.3%
** SES AI Corp  SES.N , down 15.9%
The top three Nasdaq  .PG.O  percentage gainers:
** Hoth Therapeutics Inc  HOTH.OQ , up 192.8%
** SPI Energy Co Ltd  SPI.OQ , up 139.5%
** DatChat Inc  DATS.OQ , up 129.6%
The top three Nasdaq  .PL.O  percentage losers:
** ACELYRIN Inc  SLRN.OQ , down 36.7%
** DIH Holding US Inc  DHAI.OQ , down 36.6%
** Amesite Inc  AMST.OQ , down 33.8%
    
** Micron Technology Inc  MU.O :
BUZZ - Extends gains as chipmaker to provide memory for Nvidia's gaming chips  urn:newsml:reuters.com:*:nL4N3O30OY
    
** Aurora Innovation Inc  AUR.O :
BUZZ - Soars on partnership with Nvidia, Continental to deploy driverless trucks  urn:newsml:reuters.com:*:nL4N3O30PC
    
** Inari Medical Inc  NARI.O :
BUZZ - Rises on $4.9 bln buyout by device maker Stryker  urn:newsml:reuters.com:*:nL4N3O30PA
    
** Uber Technologies Inc  UBER.N :
BUZZ - Aurora, Micron climb on Nvidia collabs as CES 2025 kicks off  urn:newsml:reuters.com:*:nL4N3O30QD
    
** FuboTV Inc  FUBO.N :
BUZZ - Extends gains after deal with Disney to combine live TV businesses  urn:newsml:reuters.com:*:nL4N3O31AD
    
** Wells Fargo & Co  WFC.N :
**JPMorgan Chase & Co  JPM.N :
** PNC Financial Services Group Inc  PNC.N :
BUZZ - Truist Securities says US big banks 'can keep winning', starts coverage  urn:newsml:reuters.com:*:nL4N3O30PQ
 
** Newmont Corp  NEM.N : 
** Barrick Gold Corp  GOLD.N : 
** Gold Fields Ltd  GFI.N : 
** Harmony Gold Mining Co Ltd  HMY.N : 
BUZZ - Gold miners rise as US dollar slips  urn:newsml:reuters.com:*:nL4N3O30S1
    
** Nvidia Corp  NVDA.O :
BUZZ - Gains after unveiling robot training tech, new gaming chips  urn:newsml:reuters.com:*:nL4N3O30S2
 
** Centessa Pharmaceuticals PLC  CNTA.O :
BUZZ - TD Cowen starts coverage of Centessa Pharma with 'buy'  urn:newsml:reuters.com:*:nL4N3O30UP
    
** Moderna Inc  MRNA.O :
** Novavax Inc  NVAX.O :
BUZZ - Vaccine makers gain amid growing concerns around bird flu  urn:newsml:reuters.com:*:nL4N3O30UK
    
** Lululemon Athletica Inc  LULU.O :
BUZZ - Rises after Bernstein upgrades to 'outperform'  urn:newsml:reuters.com:*:nL4N3O31B8
    
** Freeport-McMoRan Inc  FCX.N :
BUZZ - Bernstein downgrades Freeport-McMoRan to 'market-perform'; cuts PT  urn:newsml:reuters.com:*:nL4N3O30W6
    
** Getty Images Holdings Inc  GETY.N :
BUZZ - Jumps on merger with rival Shutterstock  urn:newsml:reuters.com:*:nL4N3O317Q
    
** Ross Stores Inc  ROST.O :
BUZZ - Down after Bernstein downgrades to 'market perform'  urn:newsml:reuters.com:*:nL4N3O30YG
    
** Ulta Beauty Inc  ULTA.O :
BUZZ - Rises after Q4 forecast, CEO change; brokerages raise PT  urn:newsml:reuters.com:*:nL4N3O30Y6
    
** Mesa Air Group Inc  MESA.O :
BUZZ - Gains on deals to sell 18 Embraer planes, 15 CRJ-900 airframes  urn:newsml:reuters.com:*:nL4N3O30Y7
    
** Apple Inc  AAPL.O :
BUZZ - Dips as MoffettNathanson downgrades to 'sell' in contrarian view  urn:newsml:reuters.com:*:nL4N3O30YZ
    
** Denali Therapeutics Inc  DNLI.O :
BUZZ - Falls after ALS drug fails in mid-to-late stage trial  urn:newsml:reuters.com:*:nL4N3O30ZU
    
** Hims & Hers Health Inc  HIMS.N :
BUZZ - Rises after BTIG starts coverage with 'buy' rating  urn:newsml:reuters.com:*:nL4N3O30ZS
    
** Immuneering Corp  IMRX.O :
BUZZ - Soars on positive trial data for pancreatic cancer therapy  urn:newsml:reuters.com:*:nL4N3O3105
    
** Eli Lilly and Co  LLY.N :
** AstraZeneca PLC  AZN.O :
** GSK PLC  GSK.N :
** Merck & Co Inc  MRK.N :
BUZZ - Obesity drugs, M&A among key pharma drivers for 2025, Berenberg says  urn:newsml:reuters.com:*:nL8N3O30QG
    
** Bank of America Corp  BAC.N :
BUZZ - Upgraded to 'buy' rating by HSBC, UBS  urn:newsml:reuters.com:*:nL4N3O30RW
    
** UniFirst Corp  UNF.N :
BUZZ - Jumps after Cintas discloses proposal to buy co in $5.3 bln deal  urn:newsml:reuters.com:*:nL4N3O314R
    
** Southwest Airlines Co  LUV.N :
BUZZ - Enters sale/leaseback deal for 36 jets; shares down  urn:newsml:reuters.com:*:nL4N3O311E
    
** Lithium Americas Corp  LAC.N :
BUZZ - Hikes Thacker Pass reserve estimate, names CFO; shares gain  urn:newsml:reuters.com:*:nL4N3O31BO
    
** Carvana Co  CVNA.N :
BUZZ - Rises as RBC turns bullish after stock's pullback  urn:newsml:reuters.com:*:nL6N3O30GT
    
** Dutch Bros Inc  BROS.N :
BUZZ - Rises after Barclays upgrades to 'overweight', lifts PT  urn:newsml:reuters.com:*:nL4N3O3153
    
** Annovis Bio Inc  ANVS.N :
BUZZ - Rises as FDA approves late-stage Alzheimer's study protocol  urn:newsml:reuters.com:*:nL4N3O314H
    
** Hoth Therapeutics Inc  HOTH.O :
BUZZ - Rises on positive mid-stage trial data for skin toxicity treatment  urn:newsml:reuters.com:*:nL4N3O314S
    
** Serve Robotics Inc  SERV.O :
BUZZ - Slides after unveiling $80 mln stock offering  urn:newsml:reuters.com:*:nL4N3O314Z
 
** Dow Inc  DOW.N :
** LyondellBasell Industries NV  LYB.N :
** Ecolab Inc  ECL.N :
** Olin Corp  OLN.N :
BUZZ - Piper Sandler expects chemical companies to struggle to grow through 2026  urn:newsml:reuters.com:*:nL4N3O315G
    
** Paycor HCM Inc  PYCR.O :
** Paychex Inc  PAYX.O :
BUZZ - Down; Paychex strikes $4.1 bln deal to buy rival payroll firm  urn:newsml:reuters.com:*:nL4N3O316M
    
** Suncor Energy Inc  SU.N :
BUZZ - Up after Q4 rise in oil, gas production  urn:newsml:reuters.com:*:nL4N3O3185
    
** Digital Realty Trust Inc  DLR.N :
BUZZ - Climbs after UBS upgrades on AI-driven growth acceleration  urn:newsml:reuters.com:*:nL6N3O30IE
    
** Anteris Technologies Ltd  AVR.O :
BUZZ - Up as brokerages initiate coverage post-research quiet period  urn:newsml:reuters.com:*:nL4N3O317R
    
** Acelyrin Inc  SLRN.O :
BUZZ - Tumbles on concerns over new dosing regimen in eye drug trial  urn:newsml:reuters.com:*:nL4N3O310V
    
** Principal Financial Group Inc  PFG.O :
BUZZ - Rises after JPM upgrades to 'overweight'  urn:newsml:reuters.com:*:nL4N3O31AA
    
** Chemours Co  CC.N :
BUZZ - Rises after naming Google exec to board  urn:newsml:reuters.com:*:nL4N3O31FM
    
 The 11 major S&P 500 sectors:
 
 Index RIC       Index name                          Percent change %
  .SPX           S&P 500                             -0.5 
  .SPLRCT        S&P 500 Information Technology                     -1.45
  .SPLRCU        S&P 500 Utilities                                   0.01
  .SPLRCD        S&P 500 Consumer Discretionary                     -1.62
  .SPLRCM        S&P 500 Materials                                   0.41
  .SPLRCI        S&P 500 Industrials                                 0.31
  .SPLRCL        S&P 500 Communication Services                     -0.57
                 (Sector)                            
  .SPSY          S&P 500 Financials                                  0.43
  .SPLRCR        S&P 500 Real Estate                                -0.34
  .SPXHC         S&P 500 Health Care                                  0.8
  .SPLRCS        S&P 500 Consumer Staples                           -0.01
  .SPNY          S&P 500 Energy                                      1.66
 

 (Compiled by Rajarshi Roy and Siddhi Mahatole)
 ((Rajarshi.Roy@thomsonreuters.com, siddhiprabhanjan.mahatole@thomsonreuters.com))

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