Updates after markets close
May 21 (Reuters) - Britain's blue-chip stock index ended flat on Thursday, as risk sentiment remained shaky following downbeat domestic data and persisting worries that the Middle East conflict could remain deadlocked.
The FTSE 100 .FTSE closed 0.1% higher at 10,443.47 points, while the midcap FTSE 250 .FTMC gained 0.5%.
Iran's supreme leader has issued a directive that the country's near-weapons-grade uranium should not be sent abroad, Reuters reported, hardening Tehran's stance on one of the main U.S. demands at peace talks.
The prolonged conflict has already pushed up oil prices and intensified concerns about inflation.
Separately, a survey on Thursday showed that British companies were suffering the most widespread drop in activity in more than a year, due to the economic fallout from the war and political uncertainty at home.
"These figures... lend some tentative support to other evidence that suggests the conditions for a long period of high inflation are not in place," said Paul Dales, chief UK economist at Capital Economics.
Earlier this week, data showed that inflation in April was softer than expected, while the unemployment rate ticked up.
Meanwhile, factory orders in May contracted at the fastest rate since September 2020, according to the Confederation of British Industry.
Utilities .FTUB6510 were among the best-performing sectors on the day, followed by industrial metal miners .FTNMX551020 and retailers .FTNMX404010
Shares of automotive marketplace Autotrader AUTOA.L slipped 8.8% after the company reported slower sales, and were the biggest laggard on the FTSE 100.
Medical equipment and services .FTNMX201020 shares fell 1.6%, dragged down by a near 5% drop in medical equipment maker Convatec CTEC.L, which flagged margin pressure.
(Reporting by Niket Nishant and Shashwat Chauhan in Bengaluru; Editing by Vijay Kishore and Alex Richardson)
((Niket.Nishant@thomsonreuters.com;))