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RNS Number : 0074F Avacta Group PLC 27 October 2025
Avacta Group plc
("Avacta" or "the Group" or "the Company")
Block Listing Six Monthly Return
LONDON AND PHILADELPHIA - October 27, 2025 Avacta Therapeutics (AIM:
AVCT, 'the Company'), a clinical stage biopharmaceutical company developing
pre|CISION(®), a tumor-activated oncology delivery platform, today makes the
following notification pursuant to Schedule Six of the AIM Rules for Companies
regarding its existing block admission arrangements:
Name of applicant: Avacta Group plc
Name of scheme: EMI scheme
Period of return: From: 28 April 2025 27 October 2025
Balance of unallotted securities under scheme(s) from previous return: 228,380
Plus: The amount by which the block scheme(s) has been increased since nil
the date of the last return (if any increase has been applied for):
Less: Number of securities issued/allotted under scheme(s) during 103,822
period (see LR3.5.7G):
Equals: Balance under scheme(s) not yet issued/allotted at end of period: 124,558
Name of applicant: Avacta Group plc
Name of scheme: LTIP/ESOS scheme
Period of return: From: 28 April 2025 27 October 2025
Balance of unallotted securities under scheme(s): 1,546,375
Plus: The amount by which the block scheme(s) has been increased since 6,500,000
the date of the last return (if any increase has been applied for):
Less: Number of securities issued/allotted under scheme(s) during 6,862,713
period (see LR3.5.7G):
Equals: Balance under scheme(s) not yet issued/allotted at end of period: 1,183,662
Name of contact: Brian Hahn, Company Secretary
Telephone number of contact: + 44 (0) 1904 217070
Ends-
For further information from Avacta Group plc, please contact:
Avacta Group plc https://avacta.com/ (https://avacta.com/)
Christina Coughlin, Chief Executive Officer via ICR Healthcare
Peel Hunt (Nomad and Joint Broker) www.peelhunt.com (http://www.peelhunt.com)
James Steel / Chris Golden
Panmure Liberum (Joint Broker) www.panmureliberum.com (http://www.panmureliberum.com)
Emma Earl / Will Goode / Mark Rogers
Zeus (Joint Broker) www.zeuscapital.co.uk (http://www.zeuscapital.co.uk)
James Hornigold / George Duxberry
Dominic King
ICR Healthcare (Europe/UK media and investors) avacta@icrhealthcare.com (mailto:avacta@icrhealthcare.com)
Mary-Jane Elliott / Jessica Hodgson / Stephanie Cuthbert
Investor Contact renee@thrustsc.com (mailto:renee@thrustsc.com)
Renee Leck
THRUST Strategic Communications
Media Contact carly@thrustsc.com (mailto:carly@thrustsc.com)
Carly Scaduto
THRUST Strategic Communications
About pre|CISION(®)
The key aspect of pre|CISION(®) is its peptide drug conjugates (PDC)
technology. The combination of the cancer drug and the proprietary cleavable
peptide (the PDC) is inert and incapable of entering cells and killing them
until the peptide is specifically released within the tumor. The active
payload in the pre|CISION(®) PDC is released when the PDC comes into contact
with the common tumor-associated protein, known as fibroblast activation
protein (FAP), in the tumor. The release of the payload from the
pre|CISION(®) product directly in the tumor results in higher concentration
of the drug at the tumor and lower blood and healthy tissue levels than
standard systemic administration, offering the potential to improve efficacy
and patient tolerability.
About Avacta - www.avacta.com (https://avacta.com/)
Avacta is a clinical stage life sciences company developing an innovative
proprietary drug delivery peptide drug conjugate (PDC) platform,
pre|CISION(®). The pre|CISION(®) platform uniquely enables the repurposing
of a range of oncology drugs as PDC payloads with the goal to significantly
reduce toxicity and side effects for patients by concentrating the drug
directly in the tumor.
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