** Shares of Avidity Biosciences RNA.O rise 21% to $35
premarket
** RNA says its experimental drug to treat a genetic
muscular disorder showed functional improvement in patients
enrolled in an early-to-mid-stage study
** The drug, delpacibart braxlosiran (AOC 1020), is being
developed to treat facioscapulohumeral muscular dystrophy (FSHD)
** AOC 1020 also showed greater than 50% reduction in
DUX4-regulated genes associated with the disorder -RNA
** Company says AOC 1020 is the first investigational
therapy to target the underlying cause of FSHD
** The drug also showed favorable safety and tolerability
with all adverse events mild or moderate -RNA
** Up to last close, stock more than tripled YTD
(Reporting by Mariam Sunny in Bengaluru)
((Mariam.ESunny@thomsonreuters.com;))