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BCYC Bicycle Therapeutics News Story

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U.S. STOCKS ON THE MOVE-Curis, Sonos, Accolade, Shopify, Hoth Therapeutics

* Eikon search string for individual stock moves:  STXBZ 
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The S&P and the Nasdaq fell more than 1% on Monday as rising bond yields weighed
on megacap growth stocks such as Microsoft, Alphabet and Apple, with investors
on edge ahead of Tuesday's inflation data.  .N 
    
    At 13:36 ET, the Dow Jones Industrial Average  .DJI  was down 0.7%. The S&P
500  .SPX  was down 1.18% at 4,435.1 and the Nasdaq Composite  .IXIC  was down
1.56% at 13,497.137.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** AT&T Inc  T.N , up 7.9%
 ** Delta Air  DAL.N , up 4.4%
 ** Ross Stores  ROST.O , up 3.5%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Occidental Petroleum Corp  OXY.N , down 6%
 ** Diamond Back Energy  FANG.OQ , down 5.3%
 ** Constellation Energy Group  CEG.OQ , down 5.2%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** Sailpoint Technologies  SAIL.N , up 29.4%
 ** Datto Holding Corp  MSP.N , up 20.6%
 ** System1 Inc  SST.N , up 17.9%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Solactive Roundhill Meme Stock TR Index  MEME.N , down 35.1%
 ** Sunland Technology Group  STG.N , down 17.3%
 ** Direxion Daily  HIBL.N , down 14.3%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Veru Inc  VERU.O , up 174.3%
 ** Iveda Solutions Inc  IVDA.O , up 54.2%
 ** VNET Group Inc   VNET.O , up 33.2%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** Singularity Future Technology  SGLY.O , down 36.4%
 ** Bicycle Therapeutics PLC  BCYC.O , down 35.6%
 ** Rubius Therapeutics  RUBY.O , down 25.2%
 
    
 ** Teck Resources Ltd  TECK.N : down 4.5%
BUZZ-Slumps on lower Q1 sales of steelmaking coal  urn:newsml:reuters.com:*:nL3N2W921W
    
 ** T. Rowe Price Group Inc  TROW.O : down 1.7%
BUZZ- Falls as Jefferies downgrades to 'hold'  urn:newsml:reuters.com:*:nL3N2W9238
    
 ** Moderna Inc  MRNA.O : down 1.3%
BUZZ-Down on recalling thousands of COVID doses in Europe  urn:newsml:reuters.com:*:nL3N2W9241
   
    
 ** Apple Inc  AAPL.O : down 1.9%
 ** Alphabet Inc  GOOGL.O : down 2.5%
 ** Microsoft Corp  MSFT.O : down 3.3%
BUZZ-Tech, growth stocks slide as yields hit multi-year high  urn:newsml:reuters.com:*:nL3N2W924Y
    
    
 ** JetBlue Airways Corp  JBLU.O : up 1.6%
BUZZ-Up 5%; trims flights on summer schedule  urn:newsml:reuters.com:*:nL3N2W925L
    
 ** Newmont Corp  NEM.N : down 1.6%
 ** Barrick Gold Corp  GOLD.N : down 0.4%
 ** Sibanye Stillwater Ltd  SBSW.N : up 1.9%
BUZZ-Gold stocks track rise in bullion prices  urn:newsml:reuters.com:*:nL3N2W929O
    
 ** Tesla Inc  TSLA.O : down 3.3%
 ** Ford Motor Co  F.N : up 2.0%
 ** General Motors Co  GM.N : up 2.7%
BUZZ-Carmakers skid as China auto sales slump in March  urn:newsml:reuters.com:*:nL3N2W926F
    
 ** Tesla Inc  TSLA.O : down 3.3%
BUZZ- Falls as China auto sales slump in March  urn:newsml:reuters.com:*:nL3N2W926R
        
 ** Veru Inc  VERU.O : up 174.3%
BUZZ-Surges as COVID-19 therapy shows promise in late-stage study  urn:newsml:reuters.com:*:nL3N2W92AP
    
    
 ** Nio Inc  NIO.N : down 0.7%
 ** Xpeng Inc  XPEV.N : down 1.3%
 ** Li Auto Inc  LI.O : down 1.8%
BUZZ-China ADRs slide as COVID-19 curbs, inflation hammer Shanghai stocks
 urn:newsml:reuters.com:*:nL3N2W92G3
    
 ** SailPoint Technologies Holdings Inc  SAIL.N : up 29.4%
BUZZ- Soars on $6.9 bln go-private deal with Thoma Bravo  urn:newsml:reuters.com:*:nL3N2W92BH
    
 ** Shopify Inc  SHOP.N : up 3.5%
BUZZ- Rises after announcing 10-for-1 stock split  urn:newsml:reuters.com:*:nL2N2W90RE
    
 ** Bicycle Therapeutics PLC  BCYC.O : down 35.6%
BUZZ-Slumps after cancer therapy data update  urn:newsml:reuters.com:*:nL3N2W92JO
    
 ** Chevron Corp  CVX.N : down 2.8%
 ** Exxon Mobil Corp  XOM.N : down 3.6%
 ** APA Corp  APA.O : down 4.5%
BUZZ-Oil cos fall as crude slips below $100 on reserves release, China lockdowns
 urn:newsml:reuters.com:*:nL3N2W92J7
    
 ** Photronics Inc  PLAB.O : up 4.0%
BUZZ-Stifel says attractive entry point, upgrades to 'buy'  urn:newsml:reuters.com:*:nL3N2W92LD
        
 ** Douyu International Holdings Ltd  DOYU.O : up 4.1%
 ** Huya Inc  HUYA.N : up 3.8%
 ** NetEase Inc  NTES.O : up 3.2%
BUZZ-Chinese gaming firms rise as regulators grant first publishing license
since July  urn:newsml:reuters.com:*:nL3N2W92N8
    
 ** Lowe's Companies Inc  LOW.N : down 1.1%
BUZZ-Down as CFO resigns to join Pfizer  urn:newsml:reuters.com:*:nL3N2W92N7
    
 ** Hoth Therapeutics Inc  HOTH.O : up 88.5%
BUZZ-Surges as cancer therapy shows promise in lab studies  urn:newsml:reuters.com:*:nL3N2W92NS
    
 ** Digital World Acquisition Corp  DWAC.O : down 1.8%
BUZZ-Trump-linked SPAC rises after one of its worst weeks urn:newsml:reuters.com:*:nL3N2W92NT
    
 ** Recursion Pharmaceutical Inc  RXRX.O : up 4.2%
BUZZ-Gains on FDA fast track tag for polyp treatment  urn:newsml:reuters.com:*:nL3N2W92Q1
    
 ** Curis Inc  CRIS.O : down 4.5%
BUZZ-Down after FDA places lymphoma drug trial on partial clinical
hold urn:newsml:reuters.com:*:nL3N2W92LI
    
 ** Nvidia Corp  NVDA.O : down 5.0%
BUZZ- Falls as Baird downgrades to "neutral", warns of order
cancellations urn:newsml:reuters.com:*:nL2N2W90YR
    
 ** BlackRock Inc  BLK.N : down 0.5%
BUZZ-JPM sees Q1 weighed down by weaker markets, cuts PT  urn:newsml:reuters.com:*:nL3N2W92K0
    
 ** Datto Holding Corp  MSP.N : up 20.6%
BUZZ-Soars on $6.2 bln takeover deal by Kaseya  urn:newsml:reuters.com:*:nL3N2W92RM
    
 ** Ameresco Inc  AMRC.N : down 11.5%
BUZZ-Slips as China COVID lockdowns to cause project delays  urn:newsml:reuters.com:*:nL3N2W92SE
    
 ** United Airlines Holdings Inc  UAL.O : up 1.6%
BUZZ-Jefferies raises PT on updated Q1 outlook  urn:newsml:reuters.com:*:nL3N2W92FZ
    
 ** LXP Industrial Trust  LXP.N : down 1.1%
BUZZ-KeyBanc downgrades after decision to suspend exploring options  urn:newsml:reuters.com:*:nL3N2W92JD
    
 ** VNET Group Inc  VNET.O : up 33.2%
BUZZ-Jumps on buyout offer  urn:newsml:reuters.com:*:nL3N2W92UO
    
 ** Archer Aviation Inc  ACHR.N : up 2.0%
 ** Joby Aviation Inc  JOBY.N : down 1.5%
BUZZ-Deutsche initiates coverage on air taxi firms  urn:newsml:reuters.com:*:nL3N2W92W0
    
 ** Zynex Inc  ZYXI.O : up 6.3%
BUZZ- Rises on $10 mln buyback plan urn:newsml:reuters.com:*:nL3N2W92T8
    
 ** Travelers Companies Inc  TRV.N : up 0.7%
 ** MetLife Inc  MET.N : up 0.1%
BUZZ-U.S. insurers gain tracking higher Treasury yields  urn:newsml:reuters.com:*:nL3N2W92WA
    
 ** Paratek Pharmaceuticals Inc  PRTK.O : down 2.3%
BUZZ-BTIG cuts PT over lead product's commercial prospects  urn:newsml:reuters.com:*:nL3N2W92X8
    
 ** Regions Financial Corp  RF.N : up 2.0%
BUZZ-Rises as Wells Fargo upgrades to 'overweight', hikes PT urn:newsml:reuters.com:*:nL3N2W92Y3
    
 ** RBB Bancorp  RBB.O : up 0.2%
BUZZ- Rises after CEO resigns following investigation urn:newsml:reuters.com:*:nL3N2W92XG

 ** Twitter Inc  TWTR.N : up 2.8%
BUZZ-Rises as analysts say Musk's board rejection opens door to bigger
stake urn:newsml:reuters.com:*:nL3N2W92WD
    
 ** Dow Inc  DOW.N : up 0.4%
BUZZ-Rises on taking minority stake in German energy hub urn:newsml:reuters.com:*:nL3N2W930F
    
 ** JPMorgan Chase & Co  JPM.N : down 0.1%
 ** Bank of America Corp  BAC.N : up 0.1%
 ** Goldman Sachs Group Inc  GS.N : up 1.0%
BUZZ-Big U.S. banks look to claw back last week's losses as yield curve
steepens urn:newsml:reuters.com:*:nL3N2W930E
    
 ** Aerojet Rocketdyne Holdings Inc  AJRD.N : up 0.5%
BUZZ-Rises on supply deal for 116 rocket engines  urn:newsml:reuters.com:*:nL3N2W934T
    
 ** First Solar Inc  FSLR.O : up 1.4%
BUZZ-Rises on solar modules orders from Origis Energy  urn:newsml:reuters.com:*:nL3N2W935F
    
 ** American Axle & Manufacturing Holdings Inc  AXL.N : up 1.6%
BUZZ-Rises on deal for Tekfor Group  urn:newsml:reuters.com:*:nL3N2W935M
    
 ** C4 Therapeutics Inc  CCCC.O : down 18.1%
BUZZ-Slumps as brokerages cut PT on dosing change for lead drug  urn:newsml:reuters.com:*:nL3N2W92MJ
    
 ** Willis Towers Watson PLC  WTW.O : down 1.2%
BUZZ-Down after BofA restarts coverage with 'underperform'  urn:newsml:reuters.com:*:nL3N2W934Z
    
 ** Ultra Clean Holdings Inc  UCTT.O : down 7.5%
BUZZ-Hits over 15-month low on lower revenue outlook  urn:newsml:reuters.com:*:nL3N2W9364

    
 ** General Motors Co  GM.N : up 2.7%
 ** Ford Motor Co  F.N : up 2.0%
BUZZ-GM, Ford outperform consumer discretionary as oil prices fall  urn:newsml:reuters.com:*:nL2N2W91BT
    
 ** Fluence Energy Inc  FLNC.O : down 6.2%
BUZZ- Sinks after more PT cuts  urn:newsml:reuters.com:*:nL3N2W936J
    
 ** Curis Inc  CRIS.O : down 4.5%
BUZZ-Down after FDA places lymphoma drug trial on partial clinical
hold urn:newsml:reuters.com:*:nL3N2W9370
    
 ** Sapiens International Corporation NV  SPNS.O : up 1.6%
BUZZ-Rises on securing contract urn:newsml:reuters.com:*:nL3N2W937M
    
 ** Sonos Inc  SONO.O : up 1.9%
BUZZ- Rises on deal to buy transducers maker Mayht  urn:newsml:reuters.com:*:nL3N2W9385
    
 ** China Automotive Systems Inc  CAAS.O : up 7.3%
BUZZ-Up on $5 mln share repurchase plan urn:newsml:reuters.com:*:nL3N2W938D
    
 ** Datto Holding Corp  MSP.N : up 20.6%
BUZZ- Soars on $6.2 bln takeover deal by Kaseya  urn:newsml:reuters.com:*:nL3N2W937E
    
 ** Accolade Inc  ACCD.O : down 7.3%
BUZZ-Wells Fargo starts coverage with 'underweight', shares down urn:newsml:reuters.com:*:nL3N2W9388
    
 ** Fastenal Co  FAST.O : up 0.8%
BUZZ-Up after UBS raises PT on higher profit estimate  urn:newsml:reuters.com:*:nL3N2W9395
    
 ** Anpac Bio Medical Sciences Co Ltd  ANPC.O : up 14.0%
BUZZ-Jumps on $15 million equity investment agreement  urn:newsml:reuters.com:*:nL3N2W9396
    
 ** Coinbase Global Holdings Inc  COIN.O : down 3.3%
BUZZ-Tumbles as India launch runs into hurdle  urn:newsml:reuters.com:*:nL3N2W9397
    
 ** Advanced Micro Devices Inc  AMD.O : down 2.7%
BUZZ-Drops to July low as investors eye GPU demand urn:newsml:reuters.com:*:nL2N2W91F5
    
 ** Exela Technologies Inc  XELA.O : up 11.0%
BUZZ-Cancels vote to effect reverse stock split, shares rise urn:newsml:reuters.com:*:nL3N2W939G
    
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   down 0.90%
 Consumer Discretionary   .SPLRCD   down 1.20%
 Consumer Staples         .SPLRCS   down 0.27%
 Energy                   .SPNY     down 3.14%
 Financial                .SPSY     down 0.25%
 Health                   .SPXHC    down 1.51%
 Industrial               .SPLRCI   up 0.03%
 Information Technology   .SPLRCT   down 1.92%
 Materials                .SPLRCM   down 0.34%
 Real Estate              .SPLRCR   down 1.19%
 Utilities                .SPLRCU   down 1.35%
 
 (Compiled by Tiyashi Datta and Rajarshi Roy)

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