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BCYC Bicycle Therapeutics News Story

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U.S. STOCKS ON THE MOVE-First Citizens BancShares, Sarepta, Celsius Holdings

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The Nasdaq led gains among Wall Street's main indexes on Wednesday as a slightly
lower-than-expected increase in inflation last month indicated that the Federal
Reserve's rapid interest rate hikes were yielding result.  .N 
    
    At 13:37 ET, the Dow Jones Industrial Average  .DJI  was down 0.91% at
33,255.41. The S&P 500  .SPX  was down 0.44% at 4,101.05 and the Nasdaq
Composite  .IXIC  was up 0.06% at 12,186.89.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Akamai Technologies, Inc  AKAM.O , up 7.7%
 ** Illumina Inc  ILMN.O , up 5.6%
 ** ServiceNow Inc  NOW.N , up 2.7%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Axon Enterprise Inc  AXON.O , down 16.1%
 ** Catalent Inc  CTLT.N , down 6.4%
 ** Newell Brands Inc  NWL.O , down 5.9%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** Compass Inc  COMP.N , up 31.3%
 ** InnSuites Hospitality Trust  IHT.N , up 19.1%
 ** HCI Group Inc  HCI.N , up 19%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Babylon Holdings Limited  BBLN.N , down 69.9%
 ** ProAssurance Corporation  PRA.N , down 22.9%
 ** Rayonier Advanced Materials Inc  RYAM.N , down 21.7%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Harbor Custom Development Inc  HCDI.O , up 152.8%
 ** CTI BioPharma Corp  CTIC.O , up 85.1%
 ** Xometry Inc  XMTR.O , up 35.1%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** Shengfeng Development Ltd  SFWL.O , down 34.6%
 ** VYNE Therapeutics Inc  VYNE.O , down 25.9%
 ** Cytek Biosciences Inc  CTKB.O , down 25.1%
 

 ** CTI BioPharma Corp  CTIC.O : up 85.1%
 BUZZ - Surges on $1.7 bln buyout offer  urn:newsml:reuters.com:*:nL4N3772EB 

 ** SmileDirectClub Inc  SDC.O : up 10.0%
 BUZZ - Shines on Q1 sales beat  urn:newsml:reuters.com:*:nL4N3772FK 
    
 ** Rivian Automotive Inc  RIVN.O : up 2.9%
 BUZZ - Gains on upbeat Q1, reaffirmed production forecast  urn:newsml:reuters.com:*:nL4N3772G6     
    
 ** Syneos Health Inc  SYNH.O : up 8.7%
 BUZZ - Gains on $4.46 bln take-private deal  urn:newsml:reuters.com:*:nL4N377333     
    
 ** Livent Corp  LTHM.N : up 5.7%
 BUZZ - Rises on merger deal with Australian lithium producer Allkem
 urn:newsml:reuters.com:*:nL4N37746C
    
 ** Upstart Holdings Inc  UPST.O : up 28.8%
 BUZZ - Surges on smaller-than-expected loss  urn:newsml:reuters.com:*:nL4N3772JH 
    
 ** Array Technologies Inc  ARRY.O : down 2.7%
 BUZZ - Falls on FY revenue forecast cut, order slowdown  urn:newsml:reuters.com:*:nL4N3772J8 
    
 ** Microvast Holdings Inc  MVST.O : up 44.7%
 BUZZ - Climbs on raising annual sales expectations  urn:newsml:reuters.com:*:nL4N3772K3 
    
 ** Protalix Biotherapeutics Inc  PLX.N : up 2.9%
 BUZZ - Jumps on FDA nod for genetic disorder therapy  urn:newsml:reuters.com:*:nL4N3772RM 
    
 ** Occidental Petroleum Corp  OXY.N : down 3.8%
 BUZZ - Slips as Q1 profit down 48%  urn:newsml:reuters.com:*:nL4N377430 
    
 ** Integral Ad Science Holding Corp  IAS.O : down 12.2%
 BUZZ - Slides on pricing Vista Equity's share sale  urn:newsml:reuters.com:*:nL1N37713O 
    
 ** Teva Pharmaceutical Industries Ltd  TEVA.N : down 8.7%
 BUZZ - Falls on Q1 net profit drop; maintains 2023 forecast  urn:newsml:reuters.com:*:nL4N3773CR 
    
 ** Airbnb Inc  ABNB.O : down 11.2%
 BUZZ - Tumbles as bookings forecast signals easing U.S. travel demand
 urn:newsml:reuters.com:*:nL1N3772BV 
    
 ** Y-mAbs Therapeutics Inc  YMAB.O : up 7.8%
 BUZZ - Rises after Wedbush upgrades to 'outperform'  urn:newsml:reuters.com:*:nL4N3773G7 
    
 ** Franchise Group Inc  FRG.O : up 1.8%
 BUZZ - Up on $2.6 bln take-private deal by CEO-led group  urn:newsml:reuters.com:*:nL4N37747A 
    
 ** Bicycle Therapeutics Plc  BCYC.O : up 5.7%
 BUZZ - Rises on cancer radiotherapy drug alliance with Bayer  urn:newsml:reuters.com:*:nL4N3773GQ 
    
 ** Icahn Enterprises LP  IEP.O : down 15.4%
 BUZZ - Slumps on fielding questions from US prosecutors  urn:newsml:reuters.com:*:nL4N3774C5 
    
 ** Rockwell Automation Inc  ROK.N : down 3.5%
 BUZZ - Fall on report co faces US probe over China operations  urn:newsml:reuters.com:*:nL4N3773HQ
    
 ** Minerva Neurosciences Inc  NERV.O : up 5.3%
 BUZZ - Rises as FDA accepts marketing application for schizophrenia drug
 urn:newsml:reuters.com:*:nL4N3773MB 
 
 ** Coherent Corp  COHR.N : down 6.7%
 BUZZ - Slumps on bleak forecast, results miss  urn:newsml:reuters.com:*:nL4N3773PE
    
 ** Wolverine Worldwide Inc  WWW.N : up 6.5%
 BUZZ - Hits 6-month high on upbeat Q1 results  urn:newsml:reuters.com:*:nL4N37747S    
    
 ** Taboola.com Ltd  TBLA.O : up 20.8%
 BUZZ - Rises on Q1 revenue beat  urn:newsml:reuters.com:*:nL4N3773TW    
    
** JPMorgan Chase & Co  JPM.N : down 1.0%
** Wells Fargo & Co  WFC.N : down 1.5%
** Goldman Sachs Group Inc  GS.N : down 1.4%
** Citigroup Inc  C.N : down 1.8%
 BUZZ - Shares of major US banks reverse course to trade lower  urn:newsml:reuters.com:*:nL4N37746P    
    
 **  Dutch Bros Inc  BROS.N : down 9.9%
 BUZZ - Slides after Q1 rev miss, Wall Street downgrades  urn:newsml:reuters.com:*:nL1N3771OW    
    
 ** Ballard Power Systems Inc  BLDP.O : down 4.2%
 BUZZ - Slides after Q1 revenue, gross margin shrink  urn:newsml:reuters.com:*:nL4N37741S    
    
 ** Marriott Vacations Worldwide Corp  VAC.N : down 3.3%
 BUZZ - Falls on CFO retirement  urn:newsml:reuters.com:*:nL4N377416    
    
 ** Akamai Technologies Inc  AKAM.O : up 7.7%
 BUZZ - Tracks best day in 3 years after strong results, forecast raise
 urn:newsml:reuters.com:*:nL4N37742X    
    
 ** New York Times Co  NYT.N : down 4.9%
 BUZZ - Drops on Q1 revenue miss  urn:newsml:reuters.com:*:nL4N37744E    
    
 ** Valens Semiconductor Ltd  VLN.N : up 4.8%
 BUZZ - Rises on smaller-than-expected loss  urn:newsml:reuters.com:*:nL4N37744U    
    
 ** Reynolds Consumer Products Inc  REYN.O : up 3.4%
 BUZZ - Hits 3-month high on Q1 revenue beat  urn:newsml:reuters.com:*:nL4N3773CT    

 ** Chevron Corp  CVX.N : down 1.8%
 ** Exxon Mobil Corp  XOM.N : down 2.1%
 ** Ovintiv Inc  OVV.N : down 2.1%
 ** ConocoPhillips  COP.N : down 1.8%
 BUZZ - Energy firms slip on surprise increase in US oil inventories
 urn:newsml:reuters.com:*:nL4N377478    
    
 ** Twilio Inc  TWLO.N : down 15.1%
 BUZZ - Hits lowest level of the year after results  urn:newsml:reuters.com:*:nL1N3771ZR    
    
 ** Telos Corp  TLS.O : up 15.2%
 BUZZ - Rises on smaller-than-expected Q1 loss, revenue beat  urn:newsml:reuters.com:*:nL4N37748G    
    
 ** RumbleOn Inc  RMBL.O : up 24.9%
 BUZZ - Rises after surprise Q1 profit  urn:newsml:reuters.com:*:nL4N37749L
    
 ** Southern Copper Corp  SCCO.N : down 7.2%
 ** Freeport-McMoRan Inc  FCX.N : down 2.5%
 ** BHP Group Ltd  BHP.N : down 2.5%
 ** Rio Tinto PLC  RIO.N : down 1.9%
 BUZZ - Copper miners fall on weak Chinese demand outlook  urn:newsml:reuters.com:*:nL4N3774BE
    
 ** Illumina Inc  ILMN.O : up 5.6%
 BUZZ - Gains after Glass Lewis backs Icahn's nominees  urn:newsml:reuters.com:*:nL4N3774BW    
    
 ** Roblox Corp  RBLX.N : up 6.6%
 BUZZ - Jumps on Q1 bookings beat, higher videogame demand  urn:newsml:reuters.com:*:nL4N3774DT    
    
 ** First Citizens BancShares Inc  FCNCA.O : up 8.7%
 BUZZ - Gains as Q1 profit jumps multi-fold  urn:newsml:reuters.com:*:nL4N3774DZ    
    
 ** ProAssurance Corp  PRA.N : down 22.9%
 BUZZ - Shares hit lowest since 2020 after results  urn:newsml:reuters.com:*:nL1N37727V    
    
 ** UWM Holdings Corp  UWMC.N : down 13.2%
 BUZZ - Falls on Q1 profit miss  urn:newsml:reuters.com:*:nL4N3774GP
    
 ** Sarepta Therapeutics Inc  SRPT.O : up 1.0%
 BUZZ - Up even as FDA staff raise doubts over gene therapy data  urn:newsml:reuters.com:*:nL4N3774GD
    
 ** Mesa Air Group Inc  MESA.O : down 32.8%
 BUZZ - Falls after wider-than-expected Q2 loss  urn:newsml:reuters.com:*:nL4N318252
    
 ** Celsius Holdings Inc  CELH.O : up 22.1%
 BUZZ - Hits record high on Q1 results beat  urn:newsml:reuters.com:*:nL4N3774I4
    
 ** Walt Disney Co  DIS.N : down 2.1%
 BUZZ - Dips ahead of report; analysts see weak rev growth  urn:newsml:reuters.com:*:nL1N3772EC
    
 ** Evolus Inc  EOLS.O : up 16.3%
 BUZZ - Surges on partnership with French firm for dermal fillers  urn:newsml:reuters.com:*:nL4N3774LC
    
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL               down 0.01%
                                    
 Consumer Discretionary   .SPLRCD               down 0.39%
                                    
 Consumer Staples         .SPLRCS               down 0.82%
                                    
 Energy                   .SPNY                 down 1.76%
                                    
 Financial                .SPSY                 down 1.35%
                                    
 Health                   .SPXHC                down 0.23%
                                    
 Industrial               .SPLRCI               down 1.35%
                                    
 Information Technology   .SPLRCT               up 0.29%
                                    
 Materials                .SPLRCM               down 0.93%
                                    
 Real Estate              .SPLRCR               up 0.38%
                                    
 Utilities                .SPLRCU               up 0.04%
                                    
 
 (Compiled by Rajarshi Roy and Ananta Agarwal in Bengaluru)
 ((Rajarshi.Roy@thomsonreuters.com))

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