** Shares of drugmaker Blueprint Medicines Corp BPMC.O
rise ~5% to $59 premarket
** The U.S. FDA late on Monday approved co's Ayvakit as the
first and only drug for the treatment of adults with indolent
systemic mastocytosis (ISM)
** Several brokerages raise PTs on co
Brokerage Prior PT New PT
Barclays $44 $46
Needham $65 $67
SVB $45 $48
Securities
Guggenheim $78 $82
** Brokerage H.C. Wainwright raises PT to $85 from $75, says
the untapped ISM market welcomes its first approval
** While the approval was broadly expected, the label
appears incrementally better than hoped or feared - TD Cowen
** Brokerage TD Cowen continues to expect Ayvakit to become
the new standard of care in moderate-severe ISM
** Brokerage Jefferies forecasts US peak sales of Ayvakit in
ISM at ~$456 million in 2030
** The drug had been approved in systemic mastocytosis, a
rare hematologic disorder, in 2021
** Up to last close, stock up ~28% YTD
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))