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March 6 (Reuters) - Wall Street's main indexes were mixed on Wednesday as investors assessed a key inflation report and the International Energy Agency's decision to release an unprecedentedamount of crude oil reserves to temper soaring energy prices amid intensifying Middle East tensions.  .N

At 11:30 EDT, the Dow Jones Industrial Average .DJI was down 0.86% at 47,294.31.The S&P 500 .SPX was down 0.33% at 6,758.83, and the Nasdaq Composite .IXIC was down 0.15% at 22,663.84.

The top three S&P 500 .PG.INX percentage gainers:

** Oracle Corp ORCL.N, up 10.5%

** CF Industries Holdings Inc CF.N, up 6.7%

** Mosaic Co MOS.N, up 5.8%

The top three S&P 500 .PL.INX percentage losers:

** Campbell's Co CPB.OQ, down 9.0%

** Fair Isaac Corp FICO.N, down 7.9%

** Ares Management Corp ARES.N, down 7.0%

   The top three NYSE .PG.N percentage gainers:

** Sos Ltd SOS.N, up 23.1%

** Auna SA AUNA.N, up 19.2%

** Hims & Hers Health Inc HIMS.N, up 11.9%

The top three NYSE .PL.N percentage losers:

** Kosmos Energy Ltd KOS.N, down 18.9%

** ATRenew Inc RERE.N, down 14.3%

** Cadre Holdings Inc CDRE.N, down 13.4%

The top three Nasdaq .PG.O percentage gainers:

** Acurx Pharmaceuticals Inc ACXP.OQ, up 66.6%

** Actelis Networks Inc ASNS.OQ, up 59.8%

** XCF Global Inc SAFX.OQ, up 38.5%

The top three Nasdaq .PL.O percentage losers:

** E-Home Household Service Holdings Ltd EJH.OQ, down 27.1%

** Focus Universal Inc FCUV.OQ, down 25.3%

** Innovation Beverage Group Ltd IBG.OQ, down 22.3%

** Oracle Corp ORCL.N:
BUZZ - Jumps on upbeat AI outlook  nL4N3ZZ0LT

**  Kosmos Energy Ltd KOS.N:
BUZZ - Slides on deep-discounted $185 mln stock sale  nL6N3ZZ0MQ

** Nike Inc NKE.N:
BUZZ - Rises as Barclays upgrades to 'overweight' nL4N3ZZ0VK

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Silvercorp Metals Inc SVM.N:

BUZZ - Silver miners fall as firmer dollar, lingering inflation concerns weigh  nL6N3ZZ0Y9

** Kala Bio Inc KALA.O:
BUZZ - Rises as it launches AI product for biotech industry  nL4N3ZZ1EE

** Diamondback Energy Inc FANG.O:
BUZZ - Drops on top holder's $1.9 bln stake sale  nL6N3ZZ0Q9

** Precision BioSciences Inc DTIL.O:
BUZZ - Rises as U.S. patents bolster experimental hepatitis B therapy  nL4N3ZZ0ZY

** Unifirst Corp UNF.N:
BUZZ - Climbs after Cintas' $5.5 billion acquisition deal  nL6N3ZZ0QG

** Campbell's Co CPB.O:
BUZZ - Drops on annual forecasts cut  nL6N3ZZ0RK

** Xenon Pharmaceuticals Inc XENE.O:
BUZZ - Dips after upsized $650 mln equity raise following epilepsy drug data  nL6N3ZZ0RV

** Booking Holdings Inc BKNG.O:

** Expedia Group Inc EXPE.O:
BUZZ - Bernstein cuts online travel agencies' PT as AI concerns loom  nL4N3ZZ113

** Dianthus Therapeutics Inc DNTH.O:
BUZZ - Slips premarket after increased $625 mln share sale  nL6N3ZZ0TQ

** Sprinklr Inc CXM.N:
BUZZ - Rises after forecasting quarterly revenue above estimates  nL6N3ZZ0TE

** Realty Income Corp O.N:
BUZZ - Mizuho raises Realty Income's PT on new acquisition strategy  nL4N3ZZ15Q

** Nebius Group NV NBIS.O:
BUZZ - Climbs after Nvidia announces $2 billion investment  nL4N3ZZ17B

** SLB NV SLB.N:
BUZZ - Dips after forecasting Q1 earnings hit due to Middle East conflict  nL6N3ZZ0UP

** CRISPR Therapeutics AG CRSP.O:
BUZZ - Steadies after boosted $550 mln convertible debt deal  nL6N3ZZ0UY

** Scienture Holdings Inc SCNX.O:
BUZZ - Rises after deals to expand reach of opioid overdose spray  nL4N3ZZ17Y

** Vistagen Therapeutics Inc VTGN.O:
BUZZ - Cuts 20% of staff to extend cash runway, shares fall  nL4N3ZZ13T

** Clearmind Medicine Inc CMND.O:
BUZZ - Rises after advancing trial of alcohol-use disorder drug nL4N3ZZ1AQ

** AeroVironment Inc AVAV.O:
BUZZ - Falls after downbeat 2026 profit forecast  nL6N3ZZ0WO

** Hyatt Hotels Corp H.N:

** Hilton Worldwide Holdings Inc HLT.N:

** Wyndham Hotels & Resorts  Inc WH.N:

** Choice Hotels International  Inc CHH.N:

BUZZ - Morgan Stanley cuts PTs on US hotels amid cautious outlook  nL4N3ZZ19Y

** Viatris Inc VTRS.O:
BUZZ - Rises as it teams up with GoodRx to offer discounts on brand‑name drugs  nL4N3ZZ1IX

** Stryker Corp SYK.N:
BUZZ - Falls after report of suspected Iran-linked cyberattack  nL6N3ZZ122

Index RICIndex namePercent change %
.SPXS&P 500-0.33
.SPLRCTS&P 500 Information Technology0.05
.SPLRCUS&P 500 Utilities-0.43
.SPLRCDS&P 500 Consumer Discretionary-0.35
.SPLRCMS&P 500 Materials-1.22
.SPLRCIS&P 500 Industrials-0.38
.SPLRCLS&P 500 Communication Services (Sector)-0.18
.SPSYS&P 500 Financials-1.27
.SPLRCRS&P 500 Real Estate-0.79
.SPXHCS&P 500 Health Care-0.46
.SPLRCSS&P 500 Consumer Staples-1.42
.SPNYS&P 500 Energy1.73
(Compiled by Rajarshi Roy and Arasu Kannagi Basil) ((ArasuKannagi.Basil@thomsonreuters.com))

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