** Shares of C4 Therapeutics CCCC.O rise 50% to $1.78
premarket, among top one-day pct gainers across U.S. stock
exchanges
** Drug developer enters into an exclusive license and
collaboration agreement with Merck MRK.N to develop a class of
cancer therapeutic agents that target cancer cells
** CCCC will receive a $10 mln upfront payment from MRK, and
is eligible to receive milestone payments totaling about $600
mln
** Under the agreement, Merck has an option to extend the
collaboration, making CCCC eligible to receive up to $2.5 bln in
potential payments
** Seven of 11 brokerages rate the stock "buy" or higher, 3
"hold" and 1 "sell"; their median PT is $8.5 - LSEG
** Up to Monday's close, stock down 80% YTD, underperforming
a 5.1% decline in the Nasdaq Biotechnology Index .NBI
(Reporting by Puyaan Singh)
((Puyaan.Singh@thomsonreuters.com;))