** Hong Kong-listed shares of China's CanSino Biologics Inc
6185.HK fall as much as 8% to HK$64.20, mark the biggest
intraday pct drop since Dec 19, if losses hold
** Stock hit the lowest since Jan 3 and is the third-biggest
pct decliner in the Hang Seng Composite Index .HSCI
** Tianjin-based Cansino Biologics estimates an up to 996
mln yuan ($147.48 mln) net loss for 2022, vs a profit of 1.9 bln
yuan in the previous year as COVID-19 vaccine demand decreases
while sales expenses increase urn:newsml:reuters.com:*:nFWN34F214
** Says demand for COVID-19 vaccines has dropped
significantly compared with a year-ago period with the growth
rate of COVID-19 vaccination worldwide decelerating while the
supply of COVID-19 vaccines exceeding demand in some regions
** Shanghai-listed shares 688185.SS drop as much as 7.6%
to 132.05 yuan, their lowest since Oct 25
** The Hang Seng Commerce & Industry Index .HSNC edges up
0.2%, while the healthcare index .HSCIH falls 1.7%
** The Hang Seng Composite Index .HSCI gains 0.3% and the
Hang Seng Index .HSI climbs 0.4%
($1 = 6.7534 Chinese yuan)
(Reporting by Donny Kwok)
((donny.kwok@thomsonreuters.com))