** U.S.-listed shares of Cardiome Pharma CRME.O rise 49.7
pct to $2.35 premarket; stock top percentage gainer
** Cipher Pharmaceuticals Inc CPH.TO to buy Cardiome's
Canadian business for C$25.5 mln ($19.53 mln), which will be
financed through a combination of cash and debt urn:newsml:reuters.com:*:nPn12WMZHa
** CRME's gains set to wipe out losses from August when U.S.
FDA declined to accept re-submission of a marketing application
for CRME's heart drug, sending shares to a nine-month low
urn:newsml:reuters.com:*:nL4N1L74AD
** Up to Monday's close, CRME stock has lost about 50 pct
over the past year
($1 = 1.3060 Canadian dollars)
(Reporting by Tamara Mathias in Bengaluru)
((Tamara.Mathias@thomsonreuters.com; within U.S. +1 646 223
8780, outside U.S. +91 806749 1208; Reuters Messaging:
tamara.mathias.thomsonreuters.com@reuters.net))