Cogent Biosciences Q4 net loss widens

Cogent Biosciences

17/02/2026 13:07

Overview

Biotech firm reported Q4 2025 net loss of $102.5 mln, increased from last year

Company maintains strong cash position with $901 mln, funding operations into 2028

Bezuclastinib NDA submissions on track for 2026, including AdvSM and GIST indications

Outlook

Cogent plans to submit APEX NDA for bezuclastinib in 1H 2026

Company aims to launch bezuclastinib in second half of 2026

Cogent expects cash runway to support operations into 2028

Result Drivers

NDA SUBMISSIONS - Cogent submitted SUMMIT NDA for bezuclastinib in NonAdvSM and initiated PEAK NDA for GIST under RTOR program

CLINICAL TRIAL PROGRESS - Bezuclastinib showed clinical benefits in SUMMIT and APEX trials, with significant symptom improvements and high response rates

FINANCIAL POSITION - Cogent maintains strong cash reserves of $901 mln, supporting operations into 2028

Key Details

Metric
Beat/Miss
Actual
Consensus Estimate
Q4 Net Income
-$102.49 mln
Q4 Income from Operations
-$99.49 mln
Q4 Operating Expenses
$99.49 mln


Analyst Coverage

The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 11 "strong buy" or "buy", 2 "hold" and no "sell" or "strong sell"

The average consensus recommendation for the biotechnology & medical research peer group is "buy"

Wall Street's median 12-month price target for Cogent Biosciences Inc is $50.50, about 38.2% above its February 13 closing price of $36.53

Press Release: ID:nGNX28xgdW

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(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)