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April 29 (Reuters) - Wall Street's main indexes fell on Wednesday as investors treaded carefully ahead of several Big Tech earnings reports and a Federal Reserve meeting expected to be the last for Jerome Powell as its Chair.  .N

At 11:30 EDT, the Dow Jones Industrial Average .DJI was down 0.54% at 48,876.52. The S&P 500 .SPX was down 0.06% at 7,134.24, and the Nasdaq Composite .IXIC was up 0.04% at 24,673.59.

The top three S&P 500 .PG.INX percentage gainers:

** NXP Semiconductors NV NXPI.OQ, up 24.0%

** Generac Holdings Inc GNRC.N, up 15.8%

** Seagate Technology Holdings PLC STX.OQ, up 14.7%

The top three S&P 500 .PL.INX percentage losers:

** Teradyne Inc TER.OQ, down 16.1%

** GE Healthcare Technologies Inc GEHC.OQ, down 13.3%

** Robinhood Markets Inc HOOD.OQ, down 13.0%

The top three NYSE .PG.N percentage gainers:

** Studio City International Holdings Ltd MSC.N, up 35.7%

** Bloom Energy Corp BE.N, up 24.9%

** Fiverr International Ltd FVRR.N, up 18.3%

The top three NYSE .PL.N percentage losers:

** Magnachip Semiconductor Corp MX.N, down 31.0%

** Clearwater Paper Corp CLW.N, down 18.9%

** SiteOne Landscape Supply Inc SITE.N, down 14.7%

The top three Nasdaq .PG.O percentage gainers:

** Rising Dragon Acquisition Corp RDAC.OQ, up 200.8%

** XTL Biopharmaceuticals Ltd XTLB.OQ, up 69.8%

** Inno Holdings Inc INHD.OQ, up 55.1%

The top three Nasdaq .PL.O percentage losers:

** Sangamo Therapeutics Inc SGMO.OQ, down 34.1%

** Cheetah Net Supply Chain Service Inc (Pre-Reincorporation) CTNT.OQ, down 26.6%

** American Rebel Holdings Inc AREB.OQ, down 26.4%

** T-Mobile US Inc TMUS.O:
BUZZ - Results set to help Deutsche Telekom nL6N41C0B4

** Seagate Technology Holdings PLC STX.O:
BUZZ - Shares surge about 18% on upbeat fourth-quarter forecast nL4N41C0K2

** NXP Semiconductors NV NXPI.O:
BUZZ - Shares rise on strong outlook nL4N41C0J4

** Robinhood Markets Inc HOOD.O:
BUZZ - Slumps on quarterly profit miss nL4N41C0KM

** Visa Inc V.N:
BUZZ - Climbs as Q2 profit tops estimates nL4N41C0LX

** Teradyne Inc TER.O:
BUZZ - Drops after weak quarterly forecast nL4N41C0P8

** O-I Glass Inc OI.N:
BUZZ - Drops after cutting FY profit forecast on geopolitical woes nL4N41C0QK

** Porch Group Inc PRCH.O:
BUZZ - Jumps after raising full-year forecasts nL4N41C0SE

** HP Inc HPQ.N:

** Micron Technology Inc MU.O:

** Western Digital Corp WDC.O:

BUZZ - Data-storage stocks jump after Seagate's upbeat outlook  nL4N41C1R6

** Starbucks Corp SBUX.O:
BUZZ - Jumps after raising annual forecasts  nL6N41C0KK

** Varonis Systems Inc VRNS.O:
BUZZ - Jumps after raising FY forecasts, surprise quarterly profit nL4N41C0W1

** Brown-Forman Corp BFb.N:
BUZZ - Falls as Pernod Ricard merger talks end nL6N41C0JF

** Humana Inc HUM.N:
BUZZ - Reaffirms annual adjusted profit forecast; shares fall nL4N41C10Q

** Enphase Energy Inc ENPH.O:
BUZZ - Slips on Q1 revenue miss nL6N41C0N5

** Biogen Inc BIIIB.O:
BUZZ - Climbs after quarterly profit beat nL4N41C12T

** Fair Isaac Corp FICO.N:
BUZZ - Rises after lifting annual forecast, topping Q2 estimates nL4N41C12U

** GE Healthcare Technologies Inc GEHC.O:
BUZZ - Slides to one-year low after Q1 profit miss, forecast cut nL4N41C1ZM

** Phillips 66 PSX.N:
BUZZ - Gains after surprise first-quarter profit nL4N41C224

** Oruka Therapeutics Inc ORKA.O:
BUZZ - Rises after upsized $700 mln stock offering nL6N41C0P8

** General Dynamics Corp GD.N:
BUZZ - Rises on higher first-quarter profit nL4N41C177

** Generac Holdings Inc GNRC.N:
BUZZ - Rises after lifting FY26 sales forecast, Q1 beat nL4N41C1A5

** Bunge Global SA BG.N:
BUZZ - Gains on higher 2026 outlook, Q1 beat nL4N41C11O

** Bloom Energy Corp BE.N:
BUZZ - Jumps after hiking 2026 revenue outlook nL6N41C0PX

** Intellia Therapeutics Inc NTLA.O:
BUZZ - Falls on $180 mln stock sale nL6N41C0QP

** KalVista Pharmaceuticals Inc KALV.O:
BUZZ - Jumps as Italy’s Chiesi to acquire it for $1.9 bln nL4N41C1FO

** AbbVie Inc ABBV.N:
BUZZ - Rises on quarterly profit beat nL4N41C1GJ

** Avis Budget Group Inc CAR.O:
BUZZ - Extends losses after quarterly results nL6N41C0RK

**  ICON PLC ICLR.O:
BUZZ - Climbs as audit probe finds revenue overstatement within limits nL4N41C1JL

** SoFi Technologies Inc SOFI.O:
BUZZ - Slips as unchanged 2026 revenue forecast disappoints nL6N41C0SC

** Cognizant Technology Solutions Corp CTSH.O:
BUZZ - Falls after weak revenue forecast  nL4N41C238

** GH Research PLC GHRS.O:
BUZZ - Eases after $117.5 mln equity raise  nL6N41C0RZ

** Old Dominion Freight Line Inc ODFL.O:
BUZZ - Rises after quarterly profit, revenue beat nL4N41C1J5

** Ingersoll Rand Inc IR.N:
BUZZ - Falls after weak annual profit forecast nL6N41C0YY

** CoStar Group Inc CSGP.O:
BUZZ - Slips after dour Q2 revenue forecast nL4N41C21W

**  Exxon Mobil Corp XOM.N:

**  Chevron Corp  CVX.N:

** Expand Energy Corp EXE.O:

** Valero Energy Corp VLO.N:
BUZZ - Oil rally lifts energy stocks, refiners lead gains nL4N41C1ZY

** Newmont Corp NEM.N:

** Harmony Gold Mining Co Ltd HMY.N:

** AngloGold Ashanti PLC AU.N:

** Gold Fields Ltd GFI.N:

BUZZ - Gold miners fall as bullion slips, Fed decision in focus nL4N41C23L

Index RICIndex namePercent change %
.SPXS&P 500-0.07
.SPLRCTS&P 500 Information Technology0.02
.SPLRCUS&P 500 Utilities-0.4
.SPLRCDS&P 500 Consumer Discretionary0.24
.SPLRCMS&P 500 Materials-0.84
.SPLRCIS&P 500 Industrials-0.76
.SPLRCLS&P 500 Communication Services (Sector)0.35
.SPSYS&P 500 Financials0.06
.SPLRCRS&P 500 Real Estate-0.59
.SPXHCS&P 500 Health Care-0.76
.SPLRCSS&P 500 Consumer Staples-0.51
.SPNYS&P 500 Energy1.37
(Compiled by Rajarshi Roy and Pranav Mathur) ((Rajarshi.Roy@thomsonreuters.com))

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