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Wall Street's main stock indexes slipped on Wednesday as comments from Federal
Reserve officials intensified worries over the central bank's rate hike path,
while Alphabet slumped on a disappointing debut of its much-awaited AI
chatbot. .N 
    At 13:41 ET, the Dow Jones Industrial Average  .DJI  was down 0.38% at
34,027.28. The S&P 500  .SPX  was down 0.97% at 4,123.57 and the Nasdaq
Composite  .IXIC  was down 1.59% at 11,921.446.
 
 The top two S&P 500  .PG.INX  percentage gainers:
 ** Fortinet Inc  FTNT.O , up 10.9%
 ** Fox Corp  FOX.O , up 5.7%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Lumen Technologies Inc   LUMN.N , down 20.7%
 ** Alphabet Inc  GOOGL.O , down 8.3%
 ** Jack Henry & Associates Inc  JKHY.O , down 8.3%
 
 The top two NYSE  .PG.N  percentage gainers:
 ** Kyndryl Holdings Inc  KD.N , up 19.5%
 ** New Relic Inc  NEWR.N , up 18.7%
 
 The top two NYSE  .PL.N  percentage losers:
 ** Capri Holdings Ltd  CPRI.N , down 28%
 ** DHI Group Inc  DHX.N , down 23.6%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** mCloud Technologies Corp  MCLDP.O , up 65.6%
 ** Kiora Pharmaceuticals Inc  KPRX.O , up 47.6%
 ** Decibel Therapeutics Inc  DBTX.O , up 20.1%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** SINTX Technologies Inc  SINT.O , down 45.9%
 ** Grom Social Enterprises Inc  GROMW.O , down 22.4%
 ** Aesther Healthcare Acquisition Corp  AEHA.O , down 22.6%
 
 
  ** Microsoft Corp  MSFT.O : up 0.3%
 BUZZ - Gains on plan for AI-powered Bing, brokerages hike PT  urn:newsml:reuters.com:*:nL4N34O2I3 
 ** Oak Street Health Inc  OSH.N : up 4.8%
 BUZZ - CVS offers to buy Oak Street Health for $9.5 bln, shares
rise urn:newsml:reuters.com:*:nL4N34O301 
 ** Manchester United PLC  MANU.N : up 13.7%
 BUZZ - Shares jump on report Qatari investors planning bid  urn:newsml:reuters.com:*:nL4N34O2MA 
 ** Evaxion Biotech A/S  EVAX.O : up 1.1%
 BUZZ - Rises on positive preclinical mRNA vaccine data  urn:newsml:reuters.com:*:nL4N34O2QP 
 ** Lumen Technologies Inc  LUMN.N : down 20.7%
 BUZZ - Falls after downbeat forecast, brokerages cut PT  urn:newsml:reuters.com:*:nL4N34O2O1 
 ** New Relic Inc  NEWR.N : up 18.7%
 BUZZ - Jumps after raising FY forecast, upbeat Q3 results  urn:newsml:reuters.com:*:nL4N34O2TZ 
 ** Capri Holdings Ltd  CPRI.N : down 28.0%
 BUZZ - Heads for worst day in three years on annual forecast cut  urn:newsml:reuters.com:*:nL4N34O3GD 
 ** Activision Blizzard Inc  ATVI.O : down 4.1%
 BUZZ - Slips as Britain's regulator says Microsoft's deal raises concerns
 urn:newsml:reuters.com:*:nL4N34O2WI 
 ** Fortinet Inc  FTNT.O : up 10.9%
 ** Palo Alto Networks Inc  PANW.O : up 4.0%
 ** Zscaler Inc  ZS.O : up 0.4%
 ** CrowdStrike Holdings Inc  CRWD.O : up 1.0%
 BUZZ - Rise after upbeat outlook from Fortinet  urn:newsml:reuters.com:*:nL4N34O2XD 
 ** Xponential Fitness Inc  XPOF.N : down 12.2%
 BUZZ - Tumbles as top holder, CEO trim stakes in secondary offering
 urn:newsml:reuters.com:*:nL1N34O0WV 
 ** Emerson Electric Co  EMR.N : down 4.7%
 BUZZ - Falls after quarterly revenue misses estimates  urn:newsml:reuters.com:*:nL4N34O2YQ 
 ** Alibaba Group Holding Ltd  BABA.N : up 0.1%
 BUZZ - Rises on news it is developing ChatGPT-type AI tool  urn:newsml:reuters.com:*:nL4N34O30I 
 ** Uber Technologies Inc  NYT.N : up 13.6%
 BUZZ - Rises on positive outlook, Q4 results beat  urn:newsml:reuters.com:*:nL4N34O2VK 
 ** Dynatrace Inc  DT.N : down 8.2%
 BUZZ - Drops as Thoma Bravo sells stock in secondary offering  urn:newsml:reuters.com:*:nL1N34O12D
 ** Teva Pharmaceutical Industries Ltd  TEVA.N : down 5.7%
 BUZZ - Falls on lower Q4 revenue  urn:newsml:reuters.com:*:nL4N34O32Y 
 ** Fox Corp  FOXA.O : up 5.3%
 BUZZ - Rises as Q2 revenue beats estimates  urn:newsml:reuters.com:*:nL4N34O358
 ** Black Hills Corp  BKH.N : down 10.0%
 BUZZ - Falls on 2023 profit forecast cut  urn:newsml:reuters.com:*:nL4N34O35T 
    
 ** Creative Medical Technology Holdings Inc  CELZ.O : up 112.6%
 BUZZ - Rises on regulatory nod for therapy trials in Type 1 diabetes
 urn:newsml:reuters.com:*:nL4N34O36T
 ** First Republic Bank  FRC.N : down 2.6%
 BUZZ - Drops on upsized $350 mln stock deal  urn:newsml:reuters.com:*:nL1N34O14M
 ** Alphabet Inc  GOOGL.O : down 8.3%
 BUZZ - Slips on Google's AI chatbot Bard fumble, Microsoft
competition urn:newsml:reuters.com:*:nL4N34O3FV
 ** Annovis Bio Inc  ANVS.N : up 3.1%
 BUZZ - Rises on clinical sites approval for Parkinson's disease study
 urn:newsml:reuters.com:*:nL4N34O3E9
 ** NeuroSense Therapeutics Ltd  NRSN.O : up 2.0%
 BUZZ - Rises on approval in Germany to enroll patients in mid-stage ALS trial
 urn:newsml:reuters.com:*:nL4N34O3FJ
 ** Argo Group International Holdings Ltd  ARGO.N : up 4.0%
 BUZZ - Rises on Brookfield Reinsurance buyout deal for $1.1 bln  urn:newsml:reuters.com:*:nL4N34O3B2 
 ** ConocoPhillips  COP.N : down 1.1%
 BUZZ - Capital One trims ConocoPhillips PT on higher spend in 2023 and beyond
 urn:newsml:reuters.com:*:nL4N34O3G1 
 ** New York Times Co  NYT.N : up 13.6%
 BUZZ - Jumps after upbeat Q4 results  urn:newsml:reuters.com:*:nL4N34O3HP 
 ** CME Group Inc  CME.O : up 4.9%
 BUZZ - Rises on lower-than-expected expenditure forecast  urn:newsml:reuters.com:*:nL4N34O39W 
 ** Illumina Inc  ILMN.O : down 6.6%
 BUZZ - Falls as brokerages cut PT on concerns over profit forecast  urn:newsml:reuters.com:*:nL4N34O3AB
 ** Guardant Health Inc  GH.O : up 5.5%
 BUZZ - Rises on getting UnitedHealthcare coverage for blood test  urn:newsml:reuters.com:*:nL4N34O3HB 
 ** TripAdvisor Inc  TRIP.O : up 3.8%
 BUZZ - Hits 4-month high as BofA upgrades rating, doubles PT  urn:newsml:reuters.com:*:nL4N34O3J3 
 ** Spectrum Pharmaceuticals Inc  SPPI.O : up 10.3%
 BUZZ - Sees quicker reimbursement for neutropenia injection; shares up
 urn:newsml:reuters.com:*:nL4N34O3J1 
 ** Gulfport Energy Corp  GPOR.N : down 5.6%
 BUZZ - Dips as winter storm negatively impacts production  urn:newsml:reuters.com:*:nL4N34O3GY 
 ** B. Riley Financial Inc  RILY.O : down 9.7%
 BUZZ - Slips after Wolfpack Research takes short position  urn:newsml:reuters.com:*:nL4N34O3JX 
 ** Humana Inc  HUM.N : up 2.7%
 BUZZ - Up on 5-year agreement with U.S. primary care provider ChenMed
 urn:newsml:reuters.com:*:nL4N34O3LA 
 ** RxSight Inc  RXST.O : down 8.9%
 BUZZ - Falls on pricing $50 mln equity offering  urn:newsml:reuters.com:*:nL1N34O1NC 
 ** Dominion Energy Inc  D.N : down 4.8%
 BUZZ - Dips on downbeat Q1 forecast  urn:newsml:reuters.com:*:nL4N34O3MY 
 ** Encompass Health Corp  EHC.N : up 3.3%
 BUZZ - Rises on better-than-estimated results  urn:newsml:reuters.com:*:nL4N34O3MD 
 ** MGM Resorts International  MGM.N : down 1.5%
 BUZZ - Shares get burnt ahead of quarterly report  urn:newsml:reuters.com:*:nL1N34O1T6 
 ** Titan Medical Inc  TMDI.O : down 65.5%
 BUZZ - To prioritize asset sale, shares fall  urn:newsml:reuters.com:*:nL4N34O3NX 
 ** Robinhood Markets Inc  HOOD.O : down 0.5%
 BUZZ - Falls ahead of Q4 results  urn:newsml:reuters.com:*:nL4N34O3MO 
    
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   down 4.35%
 Consumer Discretionary   .SPLRCD   down 1.08%
 Consumer Staples         .SPLRCS   down 0.80%
 Energy                   .SPNY     down 0.58%
 Financial                .SPSY     down 0.24%
 Health                   .SPXHC    up 0.06%
 Industrial               .SPLRCI   down 0.39%
 Information Technology   .SPLRCT   down 1.03%
 Materials                .SPLRCM   down 0.47%
 Real Estate              .SPLRCR   down 0.66%
 Utilities                .SPLRCU   down 1.78%
 (Compiled by Rajarshi Roy and Anne Florentyna Gnanaraja Sekar in Bengaluru)
 ((AnneFlorentyna.GnanarajaSekar@thomsonreuters.com;))

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