** Shares of gene editing co Editas Medicine EDIT.O rise
5.4% to $6.59
** Brokerage Citi upgrades co to "buy" rating from
"neutral", citing potential for near-term share upside in two
key catalysts through the end of the year
** Brokerage sees potential readthrough from the upcoming
FDA advisory panel meeting of Vertex Pharmaceuticals VRTX.O
and CRISPR Therapeutics AG's CRSP.BN gene editing therapy
exa-cel
** The panel is scheduled to meet on Oct 31 to discuss the
therapy as a treatment of sickle cell disease (SCD), an
inherited blood disorder marked by defective hemoglobin
** EDIT is also developing a gene editing therapy for SCD
** Brokerage anticipates the updated data from EDIT's
experimental cell therapy EDIT-301 will include a meaningful
number of patients, allowing a more thorough evaluation of its
efficacy and safety profile
** EDIT-301 is being studied in early-stage trials in
patients with SCD and those with an inherited blood disorder
known as beta thalassemia
** Stock down ~26% YTD
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))