** Shares of cancer drug developer Cyteir Therapeutics Inc
CYT.O fall 9.2% to $1.39 premarket
** Company says it will be reducing its workforce by ~70%
and defer research and development activities in certain areas
to extend cash runway into 2026
** Company had 40 full-time employees, as of Dec. 31, 2021
** Cyteir estimates severance charges of $2.5 mln-$3.0 mln,
most of which to be incurred in Q1
** Company to prioritize ovarian cancer combination therapy
after noting early positive results in study; early-stage data
expected in mid-2023
** Brokerage J.P.Morgan downgrades CYT to "neutral" from
"overweight", saying ovarian cancer activity needs to be proven
out in later-stage trials before substantial credit can be
ascribed by the Street
** 2 of 4 brokerages rate the stock "buy" or higher, 2
"hold"; median PT $4 - Refinitiv
** Stock fell 74% in the last 12 months
(Reporting by Aditya Samal)
((Aditya.Samal@thomsonreuters.com))