** Shares of drug developer Magenta Therapeutics Inc
MGTA.O fall ~25% to 37 cents premarket
** Stock among top pct losers across U.S. exchanges
** Co paused dosing in its early-to-mid stage study of blood
cancer therapy MGTA-117, after a participant experienced
respiratory failure and cardiac arrest resulting in death
** The information has been reported to the U.S. FDA, says
MGTA
** MGTA-117 was being studied to treat myeloid leukemia and
myelodysplastic syndrome, types of blood and bone marrow cancer
** In Dec, co had stopped dosing in one of its cohorts after
observing dose-limiting toxicities in the second and third dosed
participants
** Stock has declined 84% in last 12 months
(Reporting by Aditya Samal)
((Aditya.Samal@thomsonreuters.com;))