** Shares of Dow DOW.N rise 2.2% to $28.39 premarket
** The chemicals company says it will eliminate around 4,500 roles and has set a target of boosting its near-term adjusted core profit by at least $2 billion
** Dow anticipates nearly $1.1 to $1.5 billion in one-time costs, including nearly $600-$800 million in severance
** Posts adjusted loss of 34 cents per share for the fourth quarter, vs analysts' estimates of a loss of 46 cents per share, according to LSEG data
** In 2025, Dow stock was down 41.7%
(Reporting by Pranav Mathur in Bengaluru)
((Pranav.Mathur@thomsonreuters.com;))