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U.S. STOCKS ON THE MOVE-Carnival Corp, RLX Technology, Kroger, Solo Brands, Brown-Forman

* Eikon search string for individual stock moves:  STXBZ 
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U.S. stock indexes struggled for direction on Wednesday after a strong start to
the week, as investors digested a fresh update on Pfizer and BioNTech's COVID-19
vaccine, while the fast-spreading Omicron variant kept bigger bets in check.
 .N 
    At 14:08 ET, the Dow Jones Industrial Average  .DJI  was down 0.13% at
35,671.97. The S&P 500  .SPX  was up 0.12% at 4,692.15 and the Nasdaq Composite
 .IXIC  was up 0.41% at 15,751.701.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Norwegian Cruise Line Holdings Ltd  NCLH.N , up 8.7%
 ** Carnival Corp  CCL.N , up 6.1%
 ** Royal Caribbean Cruises Ltd  RCL.N , up 5.3%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** NXP Semiconductors NV  NXPI.OQ , down 5.3%
 ** Kroger Co  KR.N , down 4.4%
 ** Brown-Forman Corp  BFb.N , down 3.2%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** RLX Technology Inc  RLX.N , up 24.9%
 ** Bakkt Holdings Inc  BKKT.N , up 21.3%
 ** Direxion Daily Travel & Vacation ETF  OOTO.N , up 18.8%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Weave Communications Inc  WEAV.N , down 16.4%
 ** Solo Brands Inc  DTC.N , down 10.8%
 ** Albertsons Companies Inc  ACI.N , down 9.7%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Insignia Systems Inc  ISIG.O , up 96.9%
 ** Energy Focus Inc  EFOI.O , up 62.1%
 ** Aziyo Biologics Inc  AZYO.O , up 26.1%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** Radius Health Inc  RDUS.O , down 44.3%
 ** Nuvei Corp  NVEI.O , down 33.4%
 ** Cingulte Inc  CING.O , down 31.5%
 
 
 
 ** AutoZone Inc  AZO.N : down 1.9%
 BUZZ-Street View: DIY trends to aid AutoZone sales  urn:newsml:reuters.com:*:nL4N2ST3OL
 
 ** DocuSign  DOCU.O : up 10.6%
 BUZZ-Rebounds after CEO buys nearly $5 mln worth of stock  urn:newsml:reuters.com:*:nL1N2ST1SB
 
 ** PerkinElmer Inc  PKI.N : up 2.2%
 BUZZ-Rises on launching sequencing kit to detect COVID variants urn:newsml:reuters.com:*:nL4N2ST3NQ
 
 ** Solo Brands Inc  DTC.N : down 10.8%
 BUZZ-Falls on profit miss; brokerage sees 'exceptional' long-term story
 urn:newsml:reuters.com:*:nL4N2ST3NN
 
 ** GameStop Corp  GME.N : down 1.0%
 BUZZ-PREVIEW: GameStop wavers ahead of report  urn:newsml:reuters.com:*:nL1N2ST1NZ
    
 ** Jefferies Financial Group  JEF.N : down 1.7%
 BUZZ- Falls as co cancels parties, travel due to COVID-19  urn:newsml:reuters.com:*:nL4N2ST3NB
 
 ** Meta Platforms Inc  FB.O : up 2.4%
    Apple Inc  AAPL.O : up 1.9%
    Netflix Inc  NFLX.O : up 0.9%
 BUZZ-Regulatory cloud on Chinese tech to help U.S. tech shine in 2022 -
Wedbush urn:newsml:reuters.com:*:nL4N2ST3MB
    
 ** Corcept Therapeutics Inc  CORT.O : down 21.5%
 BUZZ-Hits over 1-yr low on subpoena from New Jersey attorney office
 urn:newsml:reuters.com:*:nL4N2ST3MK
    
 ** Datadog Inc  DDOG.O : up 3.3%
 BUZZ-Gains after Berenberg raises target price  urn:newsml:reuters.com:*:nL4N2ST3K9
  
 ** Virpax Pharmaceuticals  VRPX.O : up 7.1%
 BUZZ-Rises after promising pre-clinical pain therapy data  urn:newsml:reuters.com:*:nL4N2ST37G
    
 ** Lovesac Company  LOVE.O : up 20.7%
 BUZZ-Jumps on surprise profit as showroom sales soar  urn:newsml:reuters.com:*:nL4N2ST3I8
    
 ** Prometheus Biosciences  RXDX.O : up 3.2%
 BUZZ-Soars to 6-month high as Oppenheimer upgrades stock  urn:newsml:reuters.com:*:nL4N2ST3GF  

 ** Confluent Inc  CFLT.O : down 2.8%
 BUZZ-Falls on plans to raise $1 bln  urn:newsml:reuters.com:*:nL4N2ST3GH
    
 ** Nuvei Corp  NVEI.O : down 33.4%
 BUZZ-Share value halves on short-seller's "strong sell" report  urn:newsml:reuters.com:*:nL4N2ST3CD
 
 ** Resolute Forest Products  RFP.N : up 6.8%
 BUZZ-Jumps on share buyback  urn:newsml:reuters.com:*:nL4N2ST3FI   
    
 ** Campbell Soup Co  CPB.N : up 1.9%
 BUZZ-Jumps on profit beat  urn:newsml:reuters.com:*:nL4N2ST3FD
  
 ** Neurocrine Biosciences Inc  NBIX.O : up 2.9%
 BUZZ-Up on positive study data, PT raise  urn:newsml:reuters.com:*:nL4N2ST3FB
    
 ** Roku Inc  ROKU.O : up 18.3%
 BUZZ-Up on multi-year deal with YouTube  urn:newsml:reuters.com:*:nL4N2ST3DM
 
 ** Radius Health  RDUS.O : down 44.3%
 BUZZ-Crumbles on disappointing data from osteoporosis drug study  urn:newsml:reuters.com:*:nL4N2ST3ET
    
  ** RLX Technology  RLX.N : up 24.9%
 BUZZ-Jumps on $500 mln share buyback plan  urn:newsml:reuters.com:*:nL4N2ST3DT
    
 ** ChargePoint  CHPT.N : down 3.1%
 BUZZ-Falls after wider Q3 loss, brokerage cuts PT  urn:newsml:reuters.com:*:nL4N2ST30U
  
 ** Affimed NV  AFMD.O : up 6.0%
 BUZZ-Rises on start of patient recruitment for cancer treatment study
 urn:newsml:reuters.com:*:nL4N2ST3AR
    
 ** Palisade Bio  PALI.O : up 7.9%
 BUZZ-Rises on U.S. patent for lead drug  urn:newsml:reuters.com:*:nL4N2ST358
 
 ** Verra Mobility  VRRM.O : down 3.2%
 BUZZ-Trips as Platinum Equity exits in secondary offering  urn:newsml:reuters.com:*:nL1N2ST13A
    
 ** Hoth Therapeutics  HOTH.O : up 7.4%
 BUZZ-Rises on licensing autoimmune disease drug back to Zylo  urn:newsml:reuters.com:*:nL4N2ST35M 
    
 ** GT Biopharma  GTBP.O : up 2.6%
 BUZZ-Set for best day in over 3 months on tumor therapy trial update  USN 
 
 ** Photronics Inc  PLAB.O : up 20.3%
 BUZZ-Soars on upbeat Q4 results, forecast  urn:newsml:reuters.com:*:nL4N2ST2PN
    
 ** EPAM Systems  EPAM.N : up 14.6%
 BUZZ-Set to hit 2-week high on S&P 500 inclusion  urn:newsml:reuters.com:*:nL4N2ST2ZF
  
 ** Hilton Worldwide Holdings  HLT.N : up 1.0%
    Marriott International  MAR.O : up 0.9%
    Carnival Corp  CCL.N : up 6.1%
    Spirit Airlines  SAVE.N : up 4.1%
    Tripadvisor  TRIP.O : up 2.6%
    Norwegian Cruise Line Holdings  NCLH.N : up 8.7%
    Alaska Air Group  ALK.N : up 2.7%
    Melco Resorts & Entertainment Ltd  MLCO.O : up 6.8%
 BUZZ-Travel stocks rise on positive COVID-19 vaccine news from Pfizer
 urn:newsml:reuters.com:*:nL4N2ST32I
    
 ** Stanley Black & Decker  SWK.N : up 3.8%
 BUZZ-Jumps on $3.2 bln electronic security business sale  urn:newsml:reuters.com:*:nL4N2ST34Y
    
 ** TherapeuticsMD Inc  TXMD.O : up 5.4%
 BUZZ-Rises on patent litigation settlement with Amneal  urn:newsml:reuters.com:*:nL4N2ST2Y2     
 
 ** Lexaria Bioscience Corp  LEXX.O : up 11.2%
 BUZZ-Rises after cannabis-based formulation shows promising results in study
 urn:newsml:reuters.com:*:nL4N2ST32W
 
 ** Goodyear Tire and Rubber  GT.O : up 2.4%
 BUZZ-Rises on Deutsche Bank upgrade  urn:newsml:reuters.com:*:nL4N2ST30X

 ** Starwood Property Trust  STWD.N : down 3.4%
 BUZZ-Slips after pricing $397 mln stock offering  urn:newsml:reuters.com:*:nL4N2ST2UT
 
 ** OPKO Health  OPK.O : up 3.1%
 BUZZ-Rises after U.S. FDA approves prostate cancer test  urn:newsml:reuters.com:*:nL4N2ST309
 
 ** Wynn Resorts  WYNN.O : up 2.3%
 BUZZ-Appoints new CFO, shares up  urn:newsml:reuters.com:*:nL4N2ST2WA
    
 ** Visa Inc  V.N : up 0.1%
 BUZZ-Pay for your coffee using crypto? Visa CFO bets on stablecoins
 urn:newsml:reuters.com:*:nL4N2ST2WH
 
 ** SentinelOne Inc  S.N : down 5.5%
 BUZZ-Slides on PT cuts after results, looming lock-up expiration  urn:newsml:reuters.com:*:nL4N2ST2W1
    
 ** Apple Inc  AAPL.O : up 1.9%
 BUZZ-Apple about 7% away from becoming the first $3 trln co by market value
 urn:newsml:reuters.com:*:nL4N2ST2PA
 
 ** Pfizer Inc  PFE.N : down 0.5%
    BioNTech  BNTX.O : down 2.5%
 BUZZ-Pare losses as data shows third vaccine dose quells Omicron  urn:newsml:reuters.com:*:nL4N2ST2RM
    
 ** Weibo Corp  WB.O : down 1.4%
 BUZZ-U.S.-listed shares of China's Weibo fall after Hong Kong debut
 urn:newsml:reuters.com:*:nL4N2ST2US
    
 ** Energy Transfer LP  ET.N : up 2.2%
 BUZZ-Down as CenterPoint's stake sale prices   urn:newsml:reuters.com:*:nL1N2ST0NX
    
 ** Becton, Dickinson and Co  BDX.N : down 1.5%
 BUZZ-Piper Sandler cuts to 'neutral' on margin uncertainty  urn:newsml:reuters.com:*:nL4N2ST2N4
    
 ** Stitch Fix Inc  SFIX.O : down 22.1%
 BUZZ-Down on Q1 results, Street turns cautious  urn:newsml:reuters.com:*:nL4N2ST2MD   
     
 ** JPMorgan Chase & Co  JPM.N : down 1.1%
    Goldman Sachs Group Inc  GS.N : down 0.6%
    Wells Fargo & Co  WFC.N : down 1.5%
    Bank of America Corp  BAC.N : down 0.8%
    Citigroup  C.N : down 0.2%
    Morgan Stanley  MS.N : down 0.4%
 BUZZ-Major U.S. lenders fall as Treasury yields dip  urn:newsml:reuters.com:*:nL4N2ST2MB 
    
 ** Pfizer Inc  PFE.N : down 0.5%
    BioNTech  BNTX.O : down 2.5%
 BUZZ-Fall as study shows vaccine offers partial immunity to Omicron
 urn:newsml:reuters.com:*:nL4N2ST2F1 
 
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL   up 0.55%
 Consumer Discretionary   .SPLRCD   up 0.08%
 Consumer Staples         .SPLRCS   down 0.68%
 Energy                   .SPNY     down 0.01%
 Financial                .SPSY     down 0.34%
 Health                   .SPXHC    up 0.48%
 Industrial               .SPLRCI   up 0.16%
 Information Technology   .SPLRCT   up 0.08%
 Materials                .SPLRCM   up 0.32%
 Real Estate              .SPLRCR   up 0.49%
 Utilities                .SPLRCU   up 0.12%
 
 (Compiled by Manya Saini in Bengaluru)
 ((Manya.Saini@thomsonreuters.com))

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