30 June 2023
Igraine Plc
AQSE: KING
(“Igraine” or “the Company”)
Audited Financial Statements for the Year Ended 31 December 2022
The full audited annual report can be found on the Company’s website
https://igraineplc.com.
REVIEW OF BUSINESS
The Directors have been successful in their efforts to minimise the operating
costs of the Company, whilst investments mature.
In July 2022 Sir Professor Christopher Evans, Martin Walton, Burns Singh
Tennent-Bhohi and Richard Walker all stepped down as Directors of the Company.
The Company appreciates all the efforts of the directors who stepped down,
especially Burns Singh Tennent-Bhohi who restructured the company in April
2021 and led the recapitalisation of the company in June 2021.
The Company maintains a truly exceptional working relationship with Sir
Professor Christopher Evans and Martin Walton. Despite their transition from
the board of directors, our partnership remains strong and continues to
flourish. Their extensive experience, valuable guidance, and unwavering
dedication have made an indelible impact on the Company. We are grateful for
their ongoing support.
INVESTEE COMPANY UPDATES
Excalibur Medicines Limited
Excalibur Medicines Limited (“EML”) a subsidiary of Excalibur Healthcare
Services Ltd. EML has secured exclusive rights to and owns the patents on a
drug, AZD1656, which is being developed as a potential therapeutic for
diabetics.
Igraine maintains a 2% equity interest in EML and has the rights to co-invest
in all healthcare and life-science investment opportunities sourced or
invested into by Excalibur Healthcare Services.
In August 2022, EML announced the publication in Lancet eClinicalMedicine of
the Phase 2 clinical trial, ARCADIA, which investigated AZD1656 for people
with diabetes hospitalised with COVID19.
Patients in the AZD1656 arm were observed to have lower mortality;
additionally, AZD1656 was shown to have immunomodulatory capability, as
predicted. The paper also details our sub-group analysis of patients
considered to be at higher risk of worse COVID-19 outcomes, either with
elevated IL-6 or those with low Vitamin D status.
The EML management team have continued to work on their own and through their
network including with the clinical charity, St George Street (SGS) in seeking
commercial opportunities or interest in taking the development of asset
AZD1656 following the phase II clinical trial. EML has also begun to pursue
additional potential opportunities where the asset could be tested in other
non-respiratory indications. The mechanism of action of AZD 1656 was well
observed during the trial and its anti-inflammatory effects and T-Reg
mobilisation to the point of disease suggests that it could be effective in
other areas or organs such as the heart.
As summarised in the paper: “the evidence presented here suggests that
specific activation of T-regs might suppress the inappropriate
inflammation which is the prime cause of tissue damage in autoimmune
disease.”
Oscillate Plc
During the year the Company purchased 21,475,000 shares in Oscillate Plc,
representing approximately 10.2% of Oscillate’s issued share capital.
Oscillate Plc is an investment issuer listed on the AQSE Growth Market
Exchange seeking investment in the medical cannabis sector, special situations
and investments in the medical psychedelic industry. In June 2022, the
Oscillate invested a further £350,000 in Psych Capital and Psych Capital
listed on the AQSE Exchange, at a significantly increased value per share to
the initial total investment, resulting in a profit before tax for the Company
of £572,366. As at year end Oscillate Plc’s cash position was £1,230,961.
Legacy Investment
Following the considerable work associated with the restructure of Igraine,
the Board completed an evaluation of the investment interests acquired prior
to April 2021, including holding meetings with certain board members of the
investees. Upon completing this review, the Board of Directors have deemed
them in majority as non-core to the Company in both present material value and
in contrast the Company’s revised investment strategy.
During the Financial Year, The Company exited its position in Just Bee Honey
Limited (“Just Bee”). Just Bee is a private retail business selling high
quality honey products that have a positive impact on bees. The Company sold
1,840,000 shares (9.14%) in Just Bee Ltd for a total consideration of
£26,680.00.
To the year ending 31 December 2021, the Board of Directors wrote off the
value of the loan receivable by a legacy investee, ASSIF Limited
(“ASSIF”), whilst the Board remain in contact with this investee the Board
were unsatisfied when assessing the realistic recoverability of monies lent to
this investee further compounded by ASSIF making no attempt to repay all sums
owing to date.
POST-YEAR END REVIEW
The Company continues to monitor the development of its maiden investment with
Excalibur under the Co-Investment Agreement. Results to date have been
positive as the Excalibur team progress commercialisation discussions with the
preference being that of a trade sale.
In February 2023, the Company invested £100,000 into Fixit Medical Ltd
(“Fixit”). Fixit, a research and experimental development company focused
on social sciences and humanities, is the sole owner, designer and developer
of Cingo® (“Cingo”), the next drainage catheter fixation device.
Cingo features best in class catheter fixation through a pull-force
dissipating design and an estimated two-week wear time. Cingo also boasts a
revolutionary design that protects catheters from twisting and kinking,
providing easy access to the catheter exit site for improved visibility and
cleaning, and includes a breakthrough integral shower-safe feature. Fixit CEO
and Inventor of Cingo, Dr. Robert Ward, MB BS FRCS FRCR, is a specialist in
vascular and interventional radiology and has developed the most advanced and
patient-centric drainage catheter fixation device available today. Igraine
hold 434 ordinary shares in Fixit representing 20 per cent of Fixit’s share
capital.
Executive Director, Steve Winfield, owns approximately 46% of Larvotto Group
Limited. Larvotto Group Limited itself will have a resulting holding of
approximately 34% of Fixit and acts as an unpaid operational partner and
investor of Fixit Medical Ltd.
ON BEHALF OF THE BOARD:
Mr S Grant-Rennick
Director
DIVIDENDS
The Directors do not propose a dividend in respect of the year ended 31
December 2022 (2021: £nil).
The Directors of the Company accept responsibility for the contents of this
announcement.
Igraine plc
Simon Grant-Rennick Tel: 020 7887 1401
Peterhouse Capital Ltd ( AQSE Corporate Adviser) Tel: 020 7469 0930
Guy Miller Tel: 020 7220 9795
Brefo Gyasi
Statement of Profit or Loss for the year ended 31 December 2022
2022 £ 2021 £
CONTINUING OPERATIONS
Other operating income - 19,824
Loss on revaluation of investments (107,375) (12,798)
Administrative expenses (241,315) (407,615)
OPERATING LOSS (348,690) (400,589)
Impairment of loans and trade receivables - (93,405)
Interest Income 3,329 -
LOSS BEFORE INCOME TAX (345,361) (493,994)
Income tax - -
LOSS FOR THE YEAR (345,361) (493,994)
Earnings per share expressed in pence per share:
Basic -0.004 -0.01
Diluted -0.003 -0.008
Statement of Profit or Loss and Other Comprehensive Income for the year ended 31 December 2022
2022 £ 2021 £
LOSS FOR THE YEAR (345,361) (493,994)
Other comprehensive income - -
TOTAL COMPREHENSIVE INCOME FOR THE YEAR (345,361) (493,994)
Statement of Financial Position As at 31 December 2022
2022 £ 2021 £
ASSETS
NON-CURRENT ASSETS
Property, plant and equipment - -
Investments 761,063 615,113
761,063 615,113
CURRENT ASSETS
Trade and other receivables 134,637 154,067
Investments - 7,205
Cash and cash equivalents 388,412 904,129
523,049 1,065,401
TOTAL ASSETS 1,284,112 1,680,514
EQUITY
SHAREHOLDERS' EQUITY
Called up share capital 588,786 588,786
Share premium 1,946,995 1,946,995
Other reserves 46,116 46,116
Retained earnings (1,518,066) (1,172,705)
TOTAL EQUITY 1,063,831 1,409,192
LIABILITIES
NON-CURRENT LIABILITIES
Financial liabilities - borrowings
Interest bearing loans and borrowings 29,922 38,464
CURRENT LIABILITIES
Interest bearing loans and borrowings 9,768 10,649
Trade and other payables 180,591 222,209
TOTAL LIABILITIES 220,281 271,322
TOTAL EQUITY AND LIABILITIES 1,284,112 1,680,514
Statement of Changes in Equity for the year ended 31 December 2022
Called up share capital Share premium Other reserves Retained earnings Total equity
£ £ £ £ £
Balance at 1 January 2021 554,616 26,818 - (678,711) (97,277)
Changes in equity
Deficit for the year - - - (493,994) (493,994)
Warrant and Option charge - - 46,116 - 46,116
Total comprehensive income - - 46,116 (493,994) (447,878)
Transaction cost - (178,153) - - (178,153)
Issue of share capital 34,170 2,098,330 - - 2,132,500
Balance at 31 December 2021 588,786 1,946,995 46,116 (1,172,705) 1,409,192
Changes in equity
Deficit for the year - - - (345,361) (345,361)
Balance at 31 December 2022 588,786 1,946,995 46,116 (1,518,066) 1,063,831
Statement of Cash Flows for the year ended 31 December 2022 2022 £ 2021 £
Cash flows from operating activities
Cash generated from operations (276,575) (498,688)
Net cash from operating activities (276,575) (498,688)
Cash flows from investing activities
Purchase of fixed asset investments (268,437) (600,000)
Sale of fixed asset investments 38,716 13,431
Net cash from investing activities (229,721) (586,569)
Cash flows from financing activities
Loan repayments in year (9,421) (887)
Share issue (net of share issue costs) - 1,982,462
Net cash from financing activities (9,421) (1,981,575)
(Decrease)/increase in cash and cash equivalents (515,717) 896,318
Cash and cash equivalents at beginning of year 904,129 7,811
Cash and cash equivalents at end of year 388,412 904,129
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