RCS - Faron Pharma. Oy - Faron to Host BEXMAB Webcast

Faron Pharmaceuticals OyAnnouncement

14/03/2024 07:00

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RNS Number : 7774G  Faron Pharmaceuticals Oy  14 March 2024

 

Faron Pharmaceuticals Ltd.

 

("Faron" or the "Company")

 

 

Faron to Host Webcast to Discuss Latest Data from Phase 1 Part of the BEXMAB
Study of Bexmarilimab

 

Press Release, March 14, 2024

 

TURKU, Finland / BOSTON, Massachusetts - March 14, 2024 - Faron
Pharmaceuticals Ltd. (AIM: FARN, First North: FARON), a clinical-stage
biopharmaceutical company pursuing a CLEVER approach to reprogramming myeloid
cells to activate anti-tumor immunity in hematological and solid tumor
microenvironments, today announces it will host a virtual BEXMAB update event
on Tuesday, March 19 at 11.00 EET/9am GMT, following the most recent data
cut-off and scheduled analysis.

 

Participants of the webcast will include Dr. Mika Kontro, MD, PhD, Associate
Professor at the University of Helsinki and BEXMAB Principal Investigator;
Dr. Maija Hollmen, PhD, Chief Scientific Officer at Faron, Dr Juho Jalkanen,
MD, PhD, Chief Operating Officer at Faron and members of Faron's senior
management team.

 

During the event the Company will discuss latest data from the ongoing BEXMAB
trial in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
patients, with a particular focus on the durability of remission and objective
responses following treatment with bexmarilimab in combination with standard
of care. This interactive event will also include an introduction to myeloid
leukemia, insights into bexmarilimab's unique mode of action and the Company's
latest understanding of the early and long-term efficacy of bexmarilimab
treatment. Faron will also provide an update on bexmarilimab's future
development pathway and business opportunity. Part of the discussion will be
done in Finnish and summary in English.

 

There will be an opportunity to ask questions during the webcast. To register
for the event visit: https://faron.videosync.fi/bexmab-study-update/
(https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Ffaron.videosync.fi%2Fbexmab-study-update%2F&data=05%7C02%7C%7Ccd345bd31f0143f015e908dc42948462%7Ca2d9b7a432f64a96b03727499230d5fd%7C1%7C0%7C638458452849616442%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=SeVONi2p9qeY3N2CDuwYln6jhaYDZ17DRGfmjiUo99I%3D&reserved=0)
 or contact the IR team for more information at investor.relations@faron.com
(mailto:investor.relations@faron.com) .

 

 

For more information please contact:

 

Investor Contact

LifeSci Advisors

Daniel Ferry

Managing Director

daniel@lifesciadvisors.com (mailto:daniel@lifesciadvisors.com)

+1 (617) 430-7576

 

Media Contact

ICR Consilium

Mary-Jane Elliott, David Daley, Lindsey Neville

Phone: +44 (0)20 3709 5700

E-mail: faron@consilium-comms.com (mailto:faron@consilium-comms.com)

 

Cairn Financial Advisers LLP, Nomad

Sandy Jamieson, Jo Turner

Phone: +44 (0) 207 213 0880

 

Peel Hunt LLP, Broker

Christopher Golden, James Steel

Phone: +44 (0) 20 7418 8900

 

Sisu Partners Oy, Certified Adviser on Nasdaq First North

Juha Karttunen

Phone: +358 (0)40 555 4727

Jukka Järvelä

Phone: +358 (0)50 553 8990

 

 

About BEXMAB

The BEXMAB study is an open-label Phase 1/2 clinical trial investigating
bexmarilimab in combination with standard of care (SoC) in the aggressive
hematological malignancies of acute myeloid leukemia (AML) and myelodysplastic
syndrome (MDS). The primary objective is to determine the safety and
tolerability of bexmarilimab in combination with SoC (azacitidine) treatment.
Directly targeting Clever-1 could limit the replication capacity of cancer
cells, increase antigen presentation, ignite an immune response, and allow
current treatments to be more effective. Clever-1 is highly expressed in both
AML and MDS and associated with therapy resistance, limited T cell activation
and poor outcomes.

 

About Bexmarilimab

Bexmarilimab is Faron's wholly owned, investigational immunotherapy designed
to overcome resistance to existing treatments and optimize clinical outcomes,
by targeting myeloid cell function and igniting the immune system.
Bexmarilimab binds to Clever-1, an immunosuppressive receptor found on
macrophages leading to tumor growth and metastases (i.e. helps cancer evade
the immune system). By targeting the Clever-1 receptor on macrophages,
bexmarilimab alters the tumor microenvironment, reprogramming macrophages from
an immunosuppressive (M2) state to an immunostimulatory (M1) one, upregulating
interferon production and priming the immune system to attack tumors and
sensitizing cancer cells to standard of care.

 

About Faron Pharmaceuticals Ltd.

Faron (AIM: FARN, First North: FARON) is a global, clinical-stage
biopharmaceutical company, focused on tackling cancers via novel
immunotherapies. Its mission is to bring the promise of immunotherapy to a
broader population by uncovering novel ways to control and harness the power
of the immune system. The Company's lead asset is bexmarilimab, a novel
anti-Clever-1 humanized antibody, with the potential to remove
immunosuppression of cancers through reprogramming myeloid cell function.
Bexmarilimab is being investigated in Phase I/II clinical trials as a
potential therapy for patients with hematological cancers in combination with
other standard treatments. Further information is available at www.faron.com
(http://www.faron.com) .

 

Forward-Looking Statements

Certain statements in this announcement are, or may be deemed to be,
forward-looking statements. Forward looking statements are identified by their
use of terms and phrases such as ''believe'', ''could'', "should", "expect",
"hope", "seek", ''envisage'', ''estimate'', ''intend'', ''may'', ''plan'',
''potentially'', ''will'' or the negative of those, variations or comparable
expressions, including references to assumptions. These forward-looking
statements are not based on historical facts but rather on the Directors'
current expectations and assumptions regarding the Company's future growth,
results of operations, performance, future capital and other expenditures
(including the amount, nature and sources of funding thereof), competitive
advantages, business prospects and opportunities. Such forward-looking
statements reflect the Directors' current beliefs and assumptions and are
based on information currently available to the Directors.

 

A number of factors could cause actual results to differ materially from the
results and expectations discussed in the forward-looking statements, many of
which are beyond the control of the Company. In addition, other factors which
could cause actual results to differ materially include the ability of the
Company to successfully license its programs within the anticipated timeframe
or at all, risks associated with vulnerability to general economic and
business conditions, competition, environmental and other regulatory changes,
actions by governmental authorities, the availability of capital markets or
other sources of funding, reliance on key personnel, uninsured and
underinsured losses and other factors. Although any forward-looking statements
contained in this announcement are based upon what the Directors believe to be
reasonable assumptions, the Company cannot assure investors that actual
results will be consistent with such forward-looking statements. Accordingly,
readers are cautioned not to place undue reliance on forward-looking
statements. Subject to any continuing obligations under applicable law or any
relevant AIM Rule requirements, in providing this information the Company does
not undertake any obligation to publicly update or revise any of the
forward-looking statements or to advise of any change in events, conditions or
circumstances on which any such statement is based.

 

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