** The recent three-month pullback in the SPDR S&P biotech
ETF XBI.P may spark M&A deal activity among big pharma
companies and drug developers flush with cash, Jefferies says
** XBI is down 28% from February highs as inflation and
other macroeconomic issues caused funds to rotate out of biotech
and into post-pandemic recovery areas, brokerage says
** Our analysis of biotech M&A suggests big pharma tends to
acquire during upswings, and certainly after significant
pullbacks - Jefferies
** Large biotech and pharma cos, such as Gilead Sciences Inc
GILD.O and Vertex Pharma VRTX.O , have all publicly stated
they remain very active and prioritize business development,
brokerage says
** Horizon Therapeutics HZNP.O , Arrowhead Pharma ARWR.O ,
Ultragenyx Pharma RARE.O and Fate Therapeutics FATE.O are
among brokerage's list of potential M&A targets for 2021-22
** Biogen Inc BIIB.O , which awaits the U.S. health
regulator's decision on its Alzheimer's drug candidate
aducanumab by June 7, could do deals irrespective of the
decision, Jefferies says
(Reporting by Manojna Maddipatla in Bengaluru)
((manojna.kalyani@thomsonreuters.com; within the U.S. +1 646
223 8780, outside the U.S. +91 80 6749 1692))