(Updates)
** Shares of drug developer Cassava Sciences SAVA.O
decline as much as 86% to $3.70, hitting lowest levels since
September, 2020
** Stock on track for its largest one-day percentage
decline
** Experimental Alzheimer's disease drug, simufilam, did not
meet the main and secondary goals in a late-stage study - SAVA
** Company will discontinue a second late-stage study, as
well as an open-label study of the drug
** Reviewing full data from the trial and will assess next
steps - Cassava Sciences
** Up to the previous session's close, shares up 17.6% YTD
(Reporting by Joao Manuel Mauricio and Bhanvi Satija in
Bengaluru)