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U.S. STOCKS ON THE MOVE-Netflix, Reddit, Stoke Therapeutics

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The Dow outpaced Wall Street peers in lean trading on Wednesday, boosted by
strong gains in drugmaker Merck, while investors awaited crucial economic data
and commentary from the central bank's policymakers with the long holiday
weekend approaching.  .N 
    
    At 17:31 ET, the Dow Jones Industrial Average  .DJI  was up 0.72% at
39,563.78. The S&P 500  .SPX  was up 0.36% at 5,222.4 and the Nasdaq Composite
 .IXIC  was up 0.08% at 16,328.291.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Enphase Energy  ENPH.O , up 8.3%
 ** Cintas Corp  CTAS.O , up 8%
 ** Albemarle  ALB.N , up 8%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** Arista Networks  ANET.N , down 4.1%
 ** Global Payments  GPN.N , down 4%
 ** ServiceNow  NOW.N , down 2.8%
 
 The top three NYSE  .PG.N  percentage gainers:
 ** GCT Seminconductor Holding  GCTS.N , up 464%
 ** iBio  IBIO.N , up 217.1%
 ** Cazoo Group  CZOO.N , up 66.2%
 
 The top two NYSE  .PL.N  percentage losers:
 ** Chromocell Therapeutics  CHRO.N , down 25.1%
 ** GameStop  GME.N , down 15.2%
 
 The top three Nasdaq  .PG.O  percentage gainers:
 ** Lixte Biotechnology Holdings  LIXT.O , up 49.2%
 ** Stoke Therapeutics  STOK.O , up 46.9%
 ** PAVmed  PAVM.O , up 33%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** Direct Digital Holdings  DRCT.O , down 40.9%
 ** Wetouch Technology  WETH.O , down 34.9%
 ** RYVYL  RVYL.O , down 33.2%
 
 
 ** argenx SE  ARGX.O : up 0.5%
 BUZZ - Plans to pursue efgartigimod development in SjD lift argenx shares
 urn:newsml:reuters.com:*:nL5N3G51UX 

 ** Merck & Co Inc  MRK.N : up 4.6%
 BUZZ - Hits record high as FDA approves therapy for rare lung condition
 urn:newsml:reuters.com:*:nL3N3G53B3 
    
 ** Paysign Inc  PAYS.O : up 17.4%
 BUZZ - Surges on strong revenue forecast  urn:newsml:reuters.com:*:nL3N3G03LR 
    
 ** GameStop Corp  GME.N : down 15.2%
 BUZZ - Drops as competition, slow consumer spending weigh on Q4 revenue
 urn:newsml:reuters.com:*:nL3N3G52DF 
    
 ** Forge Global Holdings Inc  FRGE.N : down 26.0%
 BUZZ - Dips after bigger-than-expected Q4 loss  urn:newsml:reuters.com:*:nL3N3G03LJ 
    
 ** Moderna Inc  MRNA.O : up 1.6%
 BUZZ - Rises on $750 mln funding agreement with Blackstone Life Sciences
 urn:newsml:reuters.com:*:nL3N3G52IU 
    
 ** Direct Digital Holdings Inc  DRCT.O : down 40.9%
 BUZZ - Falls after results, outlook miss  urn:newsml:reuters.com:*:nL3N3G52EQ 
    
 ** Kimberly-Clark Corp  KMB.N : up 0.9%
 BUZZ - Gains on business reorganization  urn:newsml:reuters.com:*:nL3N3G52OP 
    
 ** General Electric Co  GE.N : up 3.1%
 BUZZ - Wells Fargo upgrades PT on General Electric over cost cutting potential
 urn:newsml:reuters.com:*:nL3N3G52PT 
    
 ** Novocure Ltd  NVCR.O : up 17.8%
 BUZZ - Surges as cancer therapy succeeds in late-stage trial  urn:newsml:reuters.com:*:nL3N3G52R3 
    
 ** Bowman Consulting Group Ltd  BWMN.O : down 10.7%
 BUZZ - Slides on pricing $50 mln stock offering  urn:newsml:reuters.com:*:nL2N3G511S 
    
 ** Cintas Corp  CTAS.O : up 8.0%
 BUZZ - Hits record high after uniform rental firm raises annual
forecasts urn:newsml:reuters.com:*:nL3N3G53BQ 
 ** Newmont Corp  NEM.N : up 3.0%
** Barrick Gold Corp  GOLD.N : up 3.2%
** Harmony Gold Mining Co Ltd  HMY.N : up 3.5%
 ** Kinross Gold Corp  KGC.N : up 2.9%
 BUZZ - Gold miners rise on stronger bullion ahead of US inflation data
 urn:newsml:reuters.com:*:nL3N3G53CD 

 ** Roivant Sciences Ltd  ROIV.O : up 8.5%
 BUZZ - Rallies as co poised to join S&P MidCap index  urn:newsml:reuters.com:*:nL2N3G51FA 
    
 ** Liquidia Corp  LQDA.O : down 4.0%
 BUZZ - Falls as rival Merck's therapy for lung condition gets FDA approval
 urn:newsml:reuters.com:*:nL3N3G53IU 

 ** Spirit Airlines Inc  SAVE.N : down 1.5%
 BUZZ - Falls after Barclays reinstates with "underweight" rating  urn:newsml:reuters.com:*:nL3N3G53F3 
    
 ** Carnival Corp  CCL.N : up 2.9%
 BUZZ - Gains after fiscal profit forecast raise  urn:newsml:reuters.com:*:nL3N3G53Y9 

 ** Reddit Inc  RDDT.N : down 11.0%
 BUZZ - Shares down 14% in fifth day of trading  urn:newsml:reuters.com:*:nL2N3G51MR 

 ** Stoke Therapeutics Inc  STOK.O : up 46.9%
 BUZZ - Surges again after stock offering launch  urn:newsml:reuters.com:*:nL2N3G51OA 
 
    
 ** Netflix Inc  NFLX.O : down 2.2%
 BUZZ - Shares fall; Wedbush offers mixed views  urn:newsml:reuters.com:*:nL2N3G51VP 
    
 The 11 major S&P 500 sectors:
 
 Communication Services   .SPLRCL               down 0.48%
                                    
 Consumer Discretionary   .SPLRCD               up 0.84%
                                    
 Consumer Staples         .SPLRCS               up 0.67%
                                    
 Energy                   .SPNY                 up 0.36%
                                    
 Financial                .SPSY                 up 0.51%
                                    
 Health                   .SPXHC                up 0.93%
                                    
 Industrial               .SPLRCI               up 0.91%
                                    
 Information Technology   .SPLRCT               down 0.33%
                                    
 Materials                .SPLRCM               up 0.80%
                                    
 Real Estate              .SPLRCR               up 1.66%
                                    
 Utilities                .SPLRCU               up 2.09%
                                    
 
 (Compiled by Rajarshi Roy and Vallari Srivastava)
 ((Srivastava.Vallari@thomsonreuters.com;))

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