RCS - Fusion Antibodies - Bispecific designs patent application

Fusion AntibodiesAnnouncement

09/08/2022 07:00

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RNS Number : 2986V  Fusion Antibodies PLC  09 August 2022

REACH

Fusion Antibodies plc

("Fusion" or the "Company")

 9 August 2022

Bispecific designs patent application

 

Fusion Antibodies plc (AIM: FAB), specialists in pre-clinical antibody
discovery, engineering and supply for both therapeutic drug and diagnostic
applications, announces that it has submitted a patent application in respect
of the Company's bispecific designs for antigen display.

 

The Company uses antigens to generate and screen for specific antibodies
during the Antibody Discovery process. Fusion's new designs for antigens
consist of two parts; the antigen part and a "reporter" part, referred to as a
"bispecific". The Company believes that the use of a reporter part, which can
be any number of useful tags for various antibody screening assays, will
increase the success rate in identifying highly potent antibodies from
Fusion's range of Antibody Discovery technologies.

 

Simon Douglas, Chairman of Fusion, commented: "Our dedicated team of
scientists continues to work on next generation antibody discovery, and we see
significant opportunities in this field. We look forward to contributing to
the growing body of research concerning the scope of antibody production and
design, while also growing our patent portfolio."

 

Enquiries:

 

 Fusion Antibodies plc                                 www.fusionantibodies.com
 Simon Douglas, Chairman                               Via Walbrook PR

 James Fair, Chief Financial Officer

 Allenby Capital Limited                               Tel: +44 (0)20 3328 5656
 James Reeve/Vivek Bhardwaj (Corporate Finance)

 Tony Quirke (Sales and Corporate Broking)

 Walbrook PR               Tel: +44 (0)20 7933 8780 or fusion@walbrookpr.com
 Anna Dunphy                                           Mob: +44 (0)7876 741 001
 Paul McManus                                          Mob: +44 (0)7980 541 893

 

About Fusion Antibodies plc

Fusion is a Belfast-based Collaborative Research Organisation ("CRO") company,
listed on AIM, providing a range of antibody engineering services for the
development of antibodies for both therapeutic drug and diagnostic
applications.

 

Fusion provides a broad range of services in antibody generation, development,
characterisation, optimisation, and small-scale production. These services
include antigen expression, purification and sequencing, antibody humanisation
using Fusion's proprietary CDRxTM platform and cell line development,
producing antibody generating stable cell lines optimised for use downstream
by the customer to produce material for clinical trials. Since 2012, the
Company has successfully sequenced and expressed over 250 antibodies and
successfully completed over 200 humanisation projects for its international
customer base, which has included eight of the top 10 global pharmaceutical
companies by revenue.

 

At every stage, our client's vision is central to how we work in combining the
latest technological advances with cutting edge science. In this work our
world-class humanization and antibody optimization platforms harness the power
of natural somatic hypermutation (SHM) to ensure the best molecule goes to the
clinic. Fusion Antibodies' growth strategy is based on enabling Pharma and
Biotech companies get to the clinic more effectively, using molecules with
optimized therapeutic profile and enhanced potential for successful
development and approval and, ultimately, on speeding up the drug discovery
and development process. Fusion's use of SHM to create a fully human antibody
library to capture the human antibody repertoire will address a continuing
market need in antibody discovery,

 

Fusion Antibodies' emphasis on antibody therapeutics is based on the size and
growth rate in the sector, with the market valued at $135.4 billion in 2018
and forecast to surpass $300 billion by 2025, a CAGR of 14.26%. As of May
2021, there were 100 approved antibody therapies on the market and more than
570 antibody therapies in clinical development.

 

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