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RCS - Fusion Antibodies - Expansion to OptiMAL collaboration agreement

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RNS Number : 8747B  Fusion Antibodies PLC  28 August 2024

RNS REACH

 

28 August 2024

 

Fusion Antibodies plc

("Fusion" or the "Company")

 

Expansion to OptiMAL
(http://www.investegate.co.uk/announcement/rns/fusion-antibodies--fab/optimal-collaboration-agreement-/7906203)
(®
(http://www.investegate.co.uk/announcement/rns/fusion-antibodies--fab/optimal-collaboration-agreement-/7906203)
)
(http://www.investegate.co.uk/announcement/rns/fusion-antibodies--fab/optimal-collaboration-agreement-/7906203)
collaboration agreement
(http://www.investegate.co.uk/announcement/rns/fusion-antibodies--fab/optimal-collaboration-agreement-/7906203)
 

 

Fusion Antibodies plc (AIM: FAB), specialists in pre-clinical antibody
discovery, engineering and supply for both therapeutic drug and diagnostic
applications, announces an expansion to the collaboration agreement (the
"Agreement") with the National Cancer Institute ("NCI").

 

The Company has entered into a variation to the Agreement with NCI, pursuant
to which the collaboration between the parties will be expanded to include the
humanisation by Fusion of several of the NCI's existing camelid nanobodies.
Camelid nanobodies are small antibodies derived from camel species that offer
benefits in bi-specific therapies and Chimeric Antigen Receptor ("CAR")
therapies.

 

NCI, part of the US National Institutes of Health, is the US federal
government's principal agency for cancer research and training. Pursuant to
the Agreement, details of which were announced by the Company on 28 November
2023, Fusion has provided NCI with access to OptiMAL(®) for use in the
discovery of novel antibodies against targets selected by Dr. Mitchell Ho's
Lab at the NCI.

 

Richard Buick, CSO of Fusion Antibodies plc, commented: "We are excited to
deploy our class leading humanisation technology to these nanobodies developed
by Mitchell Ho's group at the NCI, as they have shown excellent activity in
published models for CAR-T therapy. We look forward to being able to assist
the NCI in their path to clinical success and to continuing to foster goodwill
with the NCI in this wider capacity."

 

Enquiries:

 

 Fusion Antibodies plc                                                          www.fusionantibodies.com
 Adrian Kinkaid, Chief Executive Officer                             Via Walbrook PR

 Stephen Smyth, Chief Financial Officer

 Allenby Capital Limited                                             Tel: +44 (0) 20 3328 5656
 James Reeve/Vivek Bhardwaj (Corporate Finance)

 Tony Quirke/Joscelin Pinnington (Sales and Corporate Broking)

 Shard Capital Partners LLP
 Damon Heath (Joint Broker)                                          Tel: +44 (0) 207 186 9952

 Walbrook PR                       Tel: +44 (0)20 7933 8780 or fusion@walbrookpr.com
 Anna Dunphy                                                                     Mob: +44 (0)7876 741 001

 

 

About Fusion Antibodies plc

 

Fusion is a Belfast based contract research organisation ("CRO") providing a
range of antibody engineering services for the development of antibodies for
both therapeutic drug and diagnostic applications.

 

The Company's ordinary shares were admitted to trading on AIM on 18 December
2017. Fusion provides a broad range of services in antibody generation,
development, production, characterisation and optimisation. These services
include antigen expression, antibody production, purification and sequencing,
antibody humanisation using Fusion's proprietary CDRx (TM) platform and the
production of antibody generating stable cell lines to provide material for
use in clinical trials. Since 2012, the Company has successfully sequenced
and expressed over 250 antibodies and successfully completed over 200
humanisation projects and has an international, blue-chip client base, which
has included eight of the top 10 global pharmaceutical companies by revenue.

 

The Company was established in 2001 as a spin out from Queen's University
Belfast. The Company's mission is to enable pharmaceutical and diagnostic
companies to develop innovative products in a timely and cost-effective manner
for the benefit of the global healthcare industry. Fusion Antibodies provides
a broad range of services in antibody generation, development, production,
characterisation and optimisation.

 

Fusion Antibodies growth strategy is based on combining the latest
technological advances with cutting edge science to deliver new platforms that
will enable Pharma and Biotech companies get to the clinic faster, with the
optimal drug candidate and ultimately speed up the drug development process.

 

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