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REG - Fusion Antibodies - Half-year Report

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RNS Number : 4785V  Fusion Antibodies PLC  04 December 2023

Prior to publication, the information contained within this announcement was
deemed by the Company to constitute inside information for the purposes of
Article 7 under the Market Abuse Regulations (EU) No. 596/2014 ("MAR"). With
the publication of this announcement, this information is now considered to be
in the public domain.

 

4 December 2023

 

Fusion Antibodies plc

("Fusion" or the "Company")

 

Half year Report

 

Fusion Antibodies plc (AIM: FAB), an Early Discovery Contract Research
Organisation ("CRO") specialising in pre-clinical antibody discovery,
engineering and supply for both therapeutic drug and diagnostic applications,
announces its unaudited interim results for the six months ended 30 September
2023 ("H1 FY2024") and provides an update on recent commercial progress.

 

Operational highlights

·    Increased numbers of commercial opportunities identified and
improving pipeline valuation

·    A number of projects delayed by clients as they seek further
investment

·    Progress in development of the OptiMAL® library, with demonstration
of whole IgG antibodies expressed on the cell surface

·    £1.67 million fundraise alongside £1.6 million cost rationalisation
exercise

·    Appointment of Stephen Smyth as interim CFO

 

Financial highlights

·    Revenue of £541k (H1 FY2023: £1.9 million)

·    Expenditure on R&D decreased by 60% to £0.18 million (H1 FY2023:
£0.45 million)

·    Loss of £1.4 million (H1 FY2023: £1.1 million loss)

·    Cash position at 30 September 2023 was £0.5 million (31 March 2023:
£0.2 million)

 

Post-period highlights

·    Collaboration Agreement with the National Cancer Institute, USA
("NCI") to validate OptiMAL®

·    First AI/ML-Ab(TM) project successfully completed

·    Further pipeline progression and increased rate of deal closures

·    FY2024 results expected to be significantly weighted towards the
second half of the year

 

Commenting on the interim results, Adrian Kinkaid, CEO of Fusion Antibodies
plc, said: "During this calendar year, the industry has been experiencing
significant headwinds especially in the venture capital ("VC") funded biotech
sector. A number of clients have consequently delayed initiating their
projects with us. Nonetheless, we have generated a significantly stronger
pipeline which includes a wider diversity of clients that are less dependent
on VC funding. Consequently, whilst overall revenues for the period are low as
previously announced, through our efforts we have benefitted from a trend of
increasing month-on-month revenues throughout the H1 FY2024 period, which we
hope will continue to strengthen in the remainder H2 and beyond.

 

"It is particularly encouraging to see our newer offerings also being well
received with our first AI/ML-Ab(TM) contract being successfully completed
and, post-period end, securing the agreement with the NCI to help validate
OptiMAL®. Both of these developments are having a positive impact on market
awareness and engagement."

 

Investor presentation via Investor Meet Company

 

Fusion will host a presentation on the results open to all investors via the
Investor Meet Company platform at 11.00 a.m. on Thursday, 7(th) December 2023,
delivered by Dr Adrian Kinkaid, CEO and Mr Stephen Smyth, CFO. The Company is
committed to providing an opportunity for all existing and potential investors
to hear directly from management on its results whilst additionally providing
an update on the business and current trading.

 

Investors can sign up to Investor Meet Company for free and add to meet Fusion
Antibodies plc via the following
link: https://www.investormeetcompany.com/fusion-antibodies-plc/register-investor
(https://www.investormeetcompany.com/fusion-antibodies-plc/register-investor)
 

 

Enquiries:

 

 Fusion Antibodies plc                                             www.fusionantibodies.com (http://www.fusionantibodies.com)
 Adrian Kinkaid PhD, Chief Executive Officer                       Via Walbrook PR
 Stephen Smyth, Chief Financial Officer

 Allenby Capital Limited                                           Tel: +44 (0)20 3328 5656
 James Reeve / Vivek Bhardwaj (Corporate Finance)
 Tony Quirke/Joscelin Pinnington (Sales and Corporate Broking)

 Walbrook PR                      Tel: +44 (0)20 7933 8780 or fusion@walbrookpr.com
 Anna Dunphy                      Mob: +44 (0)7876 741 001

 

About Fusion Antibodies plc

 

Fusion is a Belfast-based Collaborative Research Organisation ("CRO") company,
listed on AIM, providing an integrated end-to-end range of antibody
engineering services for the development of antibodies for both therapeutic
drug and diagnostic applications.

 

Fusion provides a broad range of services in antibody generation, development,
characterisation, optimisation, and small-scale production. These services
include antigen expression, purification and sequencing, antibody humanisation
using Fusion's proprietary CDRx(TM) platform and cell line development,
producing antibody generating stable cell lines optimised for use downstream
by the customer to produce material for clinical trials. Since 2012, the
Company has successfully sequenced and expressed over 250 antibodies and
successfully completed over 200 humanisation projects for its international
customer base, which has included eight of the top 10 global pharmaceutical
companies by revenue.

 

At every stage, our client's vision is central to how we work in combining the
latest technological advances with cutting edge science. In this work our
world-class humanization and antibody optimization platforms harness the power
of natural somatic hypermutation (SHM) to ensure the best molecule goes to the
clinic. Fusion Antibodies' growth strategy is based on enabling Pharma and
Biotech companies get to the clinic more effectively, using molecules with
optimized therapeutic profile and enhanced potential for successful
development and approval and, ultimately, on speeding up the drug discovery
and development process. The announced Integrated Therapeutic Antibody
Services ("ITA") offering will enhance the efficiency of this process by
providing a continuous service offering from target nomination to stable cell
line. Fusion's use of SHM to create a fully human antibody library to capture
the human antibody repertoire will address a continuing market need in
antibody discovery.

 

Fusion Antibodies' emphasis on antibody therapeutics is based on the size and
growth rate in the sector, with the market valued at $186 billion in 2021 and
forecast to surpass $400 billion by 2028. As of June 2022, there were 150
approved antibody therapies on the market and nearly 600 antibody drugs in
clinical trials.

 

 

 

Operational Review

 

As announced on 29 September 2023, at the time of publication of its annual
report for the year ended 31 March 2023 ("FY2023"), the Company has been
experiencing a commercially challenging period, primarily due to weak market
conditions for investment in new drug discovery and development programmes and
the subsequent delays to a number of anticipated contracts, both large and
small. The Company had anticipated an easing of these constraints during H1
FY2024, however, this has not materialised as quickly as expected.
Consequently, trading conditions remain very challenging and revenue for H1
FY2024 is £541k. Towards the end of the period, several projects were subject
to certain technical challenges which required additional work to be
undertaken, thereby pushing some of the expected H1 recognised revenue into
H2. The remainder of the shortfall was due to a delayed project initiation.

 

Revenues for FY2024 are expected to be significantly weighted towards the
second half of the year, and the Board remain optimistic that our new
services, such as AI/ML-Ab(TM), will have an impact, and contribute positively
to revenue growth in the second half.  The Company has achieved a marked
growth in its pipeline of sales opportunities with overall values now standing
at approximately four times that of six months ago. Part of the pipeline
growth is attributable to enhanced penetration of adjacent markets (including
Veterinary Medicine, Diagnostics and Research Antibodies) in line with our
previously stated strategy. These factors bode well for the Company's future
provided opportunities can be progressed and converted into work in progress.

 

In June 2023, the Company successfully completed a £1.5m fundraise (net of
expenses) to provide additional working capital and we have now implemented
circa. £1.6m in restructuring savings, including a reduction in headcount
from 48 at 31 March 2023 to 29 at 30 September 2023. We are seeking to
identify additional cost savings that can be implemented without further
impacting on the operating capacity of the Company.  A significant program of
cross training of staff from different laboratories has been completed which
maintains the capability to deliver all of our services.

 

In August 2023, we announced that the negotiations with a leading AI/ML
(artificial intelligence/machine learning) company based in the USA had been
finalised and that we received our first order from this new collaboration to
generate de-novo antibody sequences.  This AI/ML platform, known as the
AI/ML-Ab(TM) service (pronounced "AIM Lab"), provides a method of designing
panels of antibodies in-silico, with the AI/ML algorithms typically producing
small libraries of sequences which are an excellent match with our Mammalian
Display platform, which emanated from the OptiMAL® library development
program.  These designs are transformed into real protein molecules for
screening and final selection and is a potentially powerful combination to
speed up the discovery process.

 

Our Integrated Therapeutic Antibody Service (ITAS) that integrates our current
Discovery, Engineering and Supply services into one proposition, continues to
gain attention and our R&D program to develop a cell-based mammalian
display technology screening library, OptiMAL®, is progressing, with key
stages of the process now developed.  As announced in our annual report for
the year ended 31 March 2023 ("FY2023"), we now have clear evidence that our
highly diverse library of DNA sequences are expressed as fully intact
antibodies on the surface of mammalian cells. With the antibody on the cell
surface, a cell can be individually selected and manipulated to produce larger
quantities of the antibody of interest, although further optimisation work is
still required to deliver the full operational screening parameters. The goal
of this cell-based process is to directly identify intact fully human
antibodies against biomarkers and other targets of interest and is in line
with the antibody drug discovery industry's aim to gradually moving away from
the use of animals.

 

We will continue to build a body of data with a view to establishing
commercial relationships for further validation and we recently announced our
first validation partner.  The Company has signed a Collaboration Agreement
(the "Agreement") with the National Cancer Institute, USA (NCI) to validate
OptiMAL®.  Under the terms of the Agreement, Fusion will provide access to
the OptiMAL® technology to NCI for the discovery of novel antibodies against
an agreed number of primarily cancer targets selected by NCI over a period of
up to two years in order to develop potential therapeutic antibodies.  The
parties will work together to ensure successful validation of the
OptiMAL® technology and jointly publish any results from the collaboration
at various times over the two-year period, although as with any R&D
project the timing of any results from the collaboration cannot be
predicted.

 

We have seen the first of the results in our strategy to grow sales through
penetration of adjacent markets. We recently announced the signing of a
commercial contract with a US-based diagnostic company to develop production
quality cell lines using our new Mammalian Display technology, for the
expressions of a range of proteins, other than antibodies, showing the
flexibility of the technology.  An initial feasibility study will be
performed on a fee-for-service basis for two difficult to produce reagents.
The study, if successful, can be expanded to a much larger portfolio of
reagents.

Board changes

Changes in the board composition during the period to September 2023 was the
appointment of Stephen Smyth as the interim CFO / Company secretary following
the resignation of James Fair (CFO).  In addition, post period end, Sonya
Ferguson stepped down as a non-Executive Director of the Company.

Financial Review

 

Revenues for the six-month period ending 30 September 2023 were £0.54 million
(H1 FY2023: £1.86 million). All revenues were derived from services and they
contained no milestone or royalty payments.

 

The (15)% gross profit percentage for H1 FY2024 (H1 FY2023: 33%) was lower
than in the same period last year due to a service based labour fixed cost in
place in readiness for an increased revenue.

 

R&D expenditure in H1 FY2024 was £182k (H1 FY2023: £452k), a decrease of
60% over the comparable period. SG&A expenditure of £1,153k was £266k
lower than in H1 FY2023 (£1,419k) and, despite significantly lower revenue
than H1 FY2023, the operating loss for H1 FY2024 was £1.36 million (H1
FY2023: £1.26 million loss). The reduction in R&D expenditure, S&G
expenditure and small increase in operating loss relative to the reduction in
revenues are all primarily due to the restructuring and cost saving measures
that were in the process of being implemented during H1 FY2024.

 

Cash used in operations was £1,213k compared with £754k used in H1 FY2023.
The H1 FY2024 operational outflow includes the £182k investment in R&D.
 The total inflow was £291k and the closing cash balance at 30 September
2023 was £487,000.

 

Key Performance Indicators

The key performance indicators (KPIs) regularly reviewed by the Board are:

 

 KPI                        H1 FY2024   H1 FY2023
 Underlying revenue growth  (71)%       (19)%
 EBITDA*                    (£1.231m)   (£1.008m)
 Cash used in operations    (£1.351m)   (£0.754m)

* Earnings before interest, tax, depreciation and amortisation

 

The investment in R&D and the impact on EBITDA is set out in Note 12 to
these statements. EBITDA for the period was a loss of £1.231 million (H1
FY2023: £1.008 million loss) and adjusting for research and development
expenditure shows an EBITDA loss excluding R&D of £1.049 million for the
period (H1 FY2023: £0.5560 million loss).

 

Outlook

 

The Board is confident that Fusion's prospects for growth are increasingly
positive and the new novel technologies available to the Company, especially
AI/ML-Ab(TM) and OptiMAL®, will play an important role in differentiating the
business and creating fresh value for our shareholders.

 

Revenues for FY2024 are expected to be significantly weighted towards the
second half of the financial year. This is supported by the revenue growth
trend observed through H1 FY2024 and the marked growth in its sales
opportunities pipeline over the last six months. Additionally, the recent news
regarding OptiMAL® has raised the Company's profile with new connections
being made with significant prospective clients, further enhancing our
strategy of penetration into adjacent markets including Veterinary Medicine,
Diagnostics and Research Antibodies.

 

It remains a key strategic focus for the Company to achieve cash neutrality.
The Company continues to maintain stringent cost controls, closely monitor the
cash runway, and will seek to identify additional cost savings that can be
implemented without further impacting the operating capacity of the Company.

 

Statement of Directors' Responsibilities

The Directors confirm, to the best of their knowledge:

 

·    The condensed set of financial statements has been prepared in
accordance with IAS34 'Interim Financial Reporting';

·    The interim management report includes a fair review of the
information required by DTR 4.2.7R of the Disclosure and Transparency Rules of
the of the United Kingdom's Financial Conduct Authority, being an indication
of important events that have occurred during the first six months of the
financial year and their impact on the condensed set of financial statements,
and a description of the principal risks and uncertainties for the remaining
six months of the year, and gives a true and fair view of the assets,
liabilities, financial positions and profit for the period of the Company; and

·    The interim management report includes a fair review of the
information required by DTR 4.2.8R of the Disclosure and Transparency Rules of
the United Kingdom's Financial Conduct Authority, being a disclosure of
related party transactions and changes therein since the previous annual
report.

 

 

 

 

On behalf of the Board

 

 

Dr Simon Douglas

Non-executive Chairman

 

04 December 2023

 

 

Condensed Statement of Comprehensive Income

For the six months ended 30 September 2023

 

 
                                                          6 months to 30.09.23  6 months to 30.09.22 Unaudited  Year to 31.03.23 Audited

                                                          Unaudited             £'000                           £'000

           £'000
                                              Notes
 Revenue                                                  541                   1,863                           2,901
 Cost of sales                                            (625)                 (1,256)                         (2,327)

 Gross profit                                             (84)                  607                             574

 Other operating income                       10          -                     8                               11
 Administrative expenses                      3           (1,335)               (1,871)                         (3,443)
 Operating loss                                           (1,419)               (1,256)                         (2,858)

 Finance income                               4           2                     1                               3
 Finance costs                                4           (3)                   (7)                             (4)
 Loss before tax                                          (1,420)               (1,262)                         (2,859)

 Income tax credit                            5           63                    146                             263

 Loss for the period                                      (1,357)               (1,116)                         (2,596)

 Total comprehensive expense for the period

                                                          (1,357)               (1,116)                         (2,596)

                                                          Pence                 Pence                           Pence
 Basic loss per share                         6           (2.3)                 (4.3)                           (10.0)

 

 

 

 

 

Condensed Statement of Financial Position

As at 30 September 2023

 

 
                                                       As at           As at 30.09.22      As at

                                                       30.09.23        Unaudited           31.03.23

       Unaudited       £'000               Audited
                                               Notes

                                                       £'000                               £'000
 Assets
 Non-current assets
 Intangible assets                                     -               -                   -
 Property, plant and equipment                 7       250             743                 375
                                                       250             743                 375
 Current assets
 Inventories                                           524             552                 539
 Trade and other receivables                           471             1,212               690
 Current tax receivable                                326             277                 263
 Cash and cash equivalents                             487             1,198               195
                                                       1,808           3,329               1,687
 Total assets                                          2,058           3,982               2,062

 Liabilities
 Current liabilities
 Trade and other payables                              537             1,057               844
 Borrowings                                    8       17              83                  35
                                                       554             1,140               879

 Net current assets                                    1,254           2,100               808

 Non-current liabilities
 Borrowings                                    8       30              250                 40
 Provisions for other liabilities and charges

                                                       20              20                  20
 Total liabilities                                     604             1,410               60

 Net assets                                            1,454           2,572               1,123

 Equity
 Called up share capital                       12      2,378           1,040               1,040
 Share premium reserve                                 7,981           7,647               7,647
 (Accumulated losses)/retained earnings

                                                       (8,905)         (6,115)             (7,564)
 Equity                                                1,454           2,572               1,123

 

 

Condensed Statement of Changes in Equity

For the six months ended 30 September 2023

 

 

 6 months ended 30 September 2023                               Called up share capital  Share premium reserve  Accumulated losses  Total

 Unaudited                                                      £'000                    £'000                  £'000               Equity

                                                                                                                                    £'000
 At 1 April 2023                                                1,040                    7,647                  (7,564)             1,123
 Loss for the period                                            -                        -                      (1,357)             (1,357)
 Issue of share capital                                         1,338                    334                    -                   1,672
 Share options - value of employee services

                                                                -                        -                      16                  16
 Total transactions with owners, recognised directly in equity

                                                                -                        -                      16                  16
 At 30 September 2023                                           2,378                    7,981                  (8,905)             1,454

 6 months ended 30 September 2022                               Called up share capital  Share premium reserve  Retained earnings   Total

 Unaudited                                                      £'000                    £'000                  £'000               Equity

                                                                                                                                    £'000
 At 1 April 2022                                                1,040                    7,647                  (5,003)             3,684
 Loss for the period                                            -                        -                      (1,116)             (1,116)
 Issue of share capital                                         -                        -                      -                   -
 Share options - value of employee services

                                                                -                        -                      4                   4
 Total transactions with owners, recognised directly in equity

                                                                -                        -                      4                   4
 At 30 September 2022                                           1,040                    7,647                  (6,115)             2,572

 Year ended 30 March 2023                                       Called up share capital  Share premium reserve  Accumulated losses  Total

 Audited                                                        £'000                    £'000                  £'000               Equity

                                                                                                                                    £'000
 At 1 April 2022                                                1,040                    7,647                  (5,003)             3,684
 Loss for the year                                              -                        -                      (2,596)             (2,596)
 Share options - value of employee services

                                                                -                        -                      35                  35
 Total transactions with owners, recognised directly in equity

                                                                -                        -                      35                  35
 At 31 March 2023                                               1,040                    7,647                  (7,564)             1,123

 

 

 

 

 

 

Statement of Cash Flows

For the six months ended 30 September 2023

 

 
                                                                6 months to  6 months to 30.09.22  Year to 31.03.23

                                                                 30.09.23    Unaudited             Audited

                                                                Unaudited    £'000                 £'000

                                                                £'000
 Cash flows from operating activities
 Loss for the period                                            (1,357)      (1,116)               (2,596)
 Adjustments for:
 Share based payment expense                                    16           4                     35
 Depreciation                                                   125          248                   372
 Amortisation of intangible assets                              -            -                     -
 Finance income                                                 (2)          (1)                   (3)
 Finance costs                                                  3            7                     4
 Income tax credit                                              (63)         (146)                 (263)
 Decrease/(increase) in inventories                             15           32                    46
 Decrease/(increase) in trade and other receivables             219          304                   819
 (Decrease)/increase in trade and other payables                (307)        (86)                  (299)
 Cash used in operations                                        (1,351)      (754)                 (1,885)
 Income tax received                                            -            -                     131
 Net cash used in operating activities                          (1,351)      (754)                 (1,754)

 Cash flows from investing activities
 Purchase of property, plant and equipment                      -            (358)                 (114)
 Finance income - interest received                             2            1                     3
 Net cash generated by/(used in) investing activities           2            (357)                 (111)

 Cash flows from financing activities
 Proceeds from issue of share capital                           1,672        -                     -
 Proceeds from new borrowings                                   -            323                   69
 Repayments of borrowings                                       (28)         (56)                  (62)
 Finance costs - interest paid                                  (3)          (7)                   (4)
 Net cash generated from financing activities                   1,641        260                   3

 Net increase/(decrease) in cash and cash equivalents           292          (851)                 1,862
 Cash and cash equivalents at the beginning of the period

                                                                195          2,049                 2,049
 Effects of exchange rate changes on cash and cash equivalents                                     8

 Cash and cash equivalents at the end of the period             487          1,198                 195

 

 

 

 

 

Notes to the Interim Results

For the six months ended 30 September 2023

 

 

1              Basis of Preparation

The condensed financial statements comprise the unaudited results for the six
months to 30 September 2023 and 30 September 2022 and the audited results for
the year ended 31 March 2023. The financial information for the year ended 31
March 2023 does not constitute the full statutory accounts for that period.
The Annual Report and Financial Statements for the year ended 31 March 2023
have been filed with the Registrar of Companies. The Independent Auditor's
Report on the Annual Report and Financial Statements for the year ended 31
March 2023 was unmodified and did not contain a statement under s498(2) or
s498(3) of the Companies Act 2006. The Auditor's report contained a material
uncertainty related to going concern.

 

The condensed financial statements for the period ended 30 September 2023 have
been prepared in accordance with the Disclosure and Transparency Rules of the
Financial Conduct Authority and with IAS 34 'Interim Financial Reporting' as
adopted by the UK. The information in these condensed financial statements
does not include all the information and disclosures made in the annual
financial statements.

 

Going concern

At 30 September 2023 the Company had a cash balance of £0.5 million. The
Directors have reviewed detailed projections for the Company. These
projections are based on estimates of future performance and have been
adjusted to reflect various scenarios and outcomes that could potentially
impact the forecast outturn. Based on these estimates, the Directors have a
reasonable expectation that the Company has adequate resources to continue in
operational existence for 12 months from the reporting date. Accordingly, they
have prepared these condensed financial statements on the going concern basis.

 

The Directors note that there is inherent uncertainty in any cash flow
forecast, however this is further exacerbated given the nature of the
Company's trade and the industry in which it operates. Due to the risk that
revenues and the related conversion of revenue to cash inflows may not be
achieved as forecast over the going concern period, the Directors believe that
there exists a material uncertainty that may cast significant doubt on the
Company's ability to continue as a going concern and it may be unable to
realise its assets and discharge its liabilities in the normal course of
business.

 

These financial statements do not include the adjustments that would result if
the Company were unable to continue as a going concern.

 

Accounting policies

The condensed financial statements have been prepared in a manner consistent
with the accounting policies set out in the financial statements for the year
ended 31 March 2023 and on the basis of the International Financial Reporting
Standards (IFRS) as adopted for use in the UK that the Company expects to be
applicable at 31 March 2023. IFRS are subject to amendment and interpretation
by the International Accounting Standards Board (IASB).

 

 

2              Segmental information

For all the financial periods included in these condensed financial
statements, all the revenues and costs relate to the single operating segment
of research, development and manufacture of recombinant proteins and
antibodies.

 

 

3              Administrative expenses

                                      6 months to 30.09.23  6 months to 30.09.22  Year to 31.03.23

                                      Unaudited             Unaudited             Audited

                                      £'000                 £'000                 £'000
 Research & development               182                   452                   807
 Selling, general and administration  1,153                 1,419                 2,636
                                      1,335                 1,871                 3,443

 

 

4              Finance income and costs

                                       6 months to 30.09.23  6 months to 30.09.22  Year to 31.03.23

                                       Unaudited             Unaudited             Audited

                                       £'000                 £'000                 £'000

 Income
 Bank interest receivable              2                     1                     3

                                       6 months to 30.09.23  6 months to 30.09.22  Year to 31.03.23

                                       Unaudited             Unaudited             Audited

                                       £'000                 £'000                 £'000

 Expense
 Interest expense on other borrowings  3                     7                     4

 

5              Income tax credit

              6 months to 30.09.23  6 months to 30.09.22  Year to 31.03.23

              Unaudited             Unaudited             Audited

              £'000                 £'000                 £'000
 Current tax  (63)                  (146)                 (263)

 

 

6              Loss per share

 

                              6 months to  6 months to 30.09.22  Year to

                              30.09.23     Unaudited             31.03.23

                              Unaudited    Number                Audited

                              Number                             Number
 Loss for the financial year  (1,357)      (1,116)               (2,596)
 Loss per share               pence        pence                 pence
 Basic                        (2.3)        (4.3)                 (10.0)
 Diluted                      (2.9)        (4.3)                 (10.0)

 

 

 

 

 

 

 

 

 

 

6              Loss per share (continued)

 

The weighted average number of shares used in the calculation of the basic
earnings per share are as follows:

 

                                                               6 months to  6 months to 30.09.22  Year to

                                                               30.09.23     Unaudited             31.03.23

                                                               Unaudited    Number                Audited

                                                               Number                             Number
 Issued ordinary shares at the end of the period

                                                               59,453,714   26,014,946            26,014,946
 Weighted average number of shares in issue during the period  46,496,775   26,014,946            26,014,946

 

Basic earnings per share is calculated by dividing the basic earnings for the
period by the weighted average number of shares in issue during the period.
Diluted earnings per share is calculated by dividing the basic earnings for
the year by the diluted weighted average number of shares in issue inclusive
of share options outstanding at year end.

 

 

7              Property, plant and equipment

                                     Right of use assets  Leasehold  Plant &      Fixtures, fittings & equipment      Total

                                     £'000                property   machinery    £'000                               £'000

                                                          £'000      £'000
 Cost
 At 1 April 2023                     14                   844        2,396        277                                 3,531
 Additions                           -                    -          -            -                                   -
 Disposals                           -                    -          -            -                                   -
 At 30 September 2023                14                   844        2,396        275                                 3,531

 Accumulated depreciation
 At 1 April 2023                     9                    812        2,112        223                                 3,156
 Disposals                           -                    -          -            -                                   -
 Depreciation charged in the period

                                     2                    17         93           13                                  125
 At 30 September 2023                11                   829        2,205        236                                 3,281

 Net book value
 At 30 September 2023                3                    15         191          41                                  250
 At 31 March 2023                    5                    32         284          54                                  375

 

 

 

 

 

 

 

 

 

 

 

8              Borrowings

                                     At 30 September  At 30 September  At 31 March

                                     2023             2022             2023

                                     £'000            £'000            £'000
 At 1 April                          75               69               69
 Additions in period                 -                323              69
 Interest                            3                7                4
 Repayments                          (31)             (66)             (67)
 At period end                       47               333              75

 Amounts due in less than 1 year     17               83               35
 Amounts due after more than 1 year  30               250              40
                                     47               333              75

 

Borrowings are secured by a fixed and floating charge over the whole
undertaking of the Company, its property, assets and rights in favour of
Northern Bank Ltd trading as Danske Bank.

9              Retirement benefits obligations

The Company operates a defined contribution scheme, the assets of which are
managed separately from the Company.

 

10           Transactions with related parties

The Company had the following transactions with related parties during the
period:

 

Invest Northern Ireland is a shareholder in the Company. The Company received
invoices for rent and estate services amounting to £38,000 (6 months ended 30
September 2022: £42,000, year ended 31 March 2023: £79,000). There was no
balance due and payable to Invest NI at the reporting dates presented.

 

11           Events after the reporting date

The Company was pleased to announce on 28(th) November 2023 that an agreement
had been established with the National Cancer Institute to help validate the
OptiMAL® platform.

 

12           Reconciliation of loss to EBITDA and EBITDA excluding
R&D expenditure

 

                                            6 months to 30.09.23  6 months to 30.09.22  Year to 31.03.23

                                            Unaudited             Unaudited             Audited

                                            £'000                 £'000                 £'000
 Loss before tax                            (1,357)               (1,262)               (2,859)
 Finance income/expense                     1                     6                     1
 Depreciation and amortisation              125                   248                   372
 EBITDA                                     (1,231)               (1,008)               (2,486)
 Expenditure on research and development    182                   452                   807
 EBITDA excluding research and development  (1,049)               (556)                 1,679

 

 

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