REG - Fusion Antibodies - R&D update: Mammalian Display service

Fusion AntibodiesAnnouncement

09/02/2023 07:00

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RNS Number : 3663P  Fusion Antibodies PLC  09 February 2023

 

 

Fusion Antibodies plc

("Fusion" or the "Company")

 

R&D update: Mammalian Display service

New commerical service from OptiMAL® programme

 

Fusion Antibodies plc (AIM: FAB), specialists in pre-clinical antibody
discovery, engineering and supply for both therapeutic drug and diagnostic
applications, announces that is has launched a new commercial service from its
R&D programme, named Mammalian Display, for high volume mammalian cell
surface expression and screening of antibodies.

 

Mammalian Display is the first service from the Company's ongoing OptiMAL®
programme which Fusion has commercialised and is now offering to clients. The
service is particularly suited to companies specialising in the identification
of therapeutic antibodies from focussed libraries of sequences, such as would
be required by those entities using artificial intelligence ("AI") or machine
learning ("ML") which can require the expression and screening of small
libraries of tens of thousands of antibodies.

 

Fusion collaborates with its clients in every stage of pre-clinical antibody
development, with decades of experience and unique proprietary platforms. A
fully integrated end-to-end service from therapeutic target nomination and
discovery through to stable cell line development in readiness for GMP
production is also available. Initial market research that the Company has
conducted with AI/ML experts has confirmed that there is a need for expression
of focussed libraries of antibodies in the way delivered by the Mammalian
Display service.

 

The Company is continuing to work on other aspects of the OptiMAL® programme,
and in particular the development of the fully human antibody library.

 

Fusion Antibodies CEO, Adrian Kinkaid said: "We are delighted to be able to
announce the successful development of the Mammalian Display technology, an
output from our OptiMAL® research programme. As our industry rapidly turns to
find new ways to hasten the development of better bio-therapeutics to the
clinic, we also anticipate deploying these capabilities to bring AI generated
antibody sequences out of world class computer algorithms and into a world
class antibody laboratory."

 

Enquiries:

 

 Fusion Antibodies plc                                www.fusionantibodies.com
 Adrian Kinkaid, Chief Executive Officer              Via Walbrook PR

 James Fair, Chief Financial Officer

 Allenby Capital Limited                              Tel: +44 (0)20 3328 5656
 James Reeve/Vivek Bhardwaj (Corporate Finance)

 Tony Quirke (Sales and Corporate Broking)

 Walbrook PR               Tel: +44 (0)20 7933 8780 or fusion@walbrookpr.com
 Anna Dunphy                                          Mob: +44 (0)7876 741 001

 

About Fusion Antibodies plc

 

Fusion is a Belfast based contract research organisation ("CRO") providing a
range of antibody engineering services for the development of antibodies for
both therapeutic drug and diagnostic applications.

 

The Company's ordinary shares were admitted to trading on AIM on 18 December
2017. Fusion provides a broad range of services in antibody generation,
development, production, characterisation and optimisation. These services
include antigen expression, antibody production, purification and sequencing,
antibody humanisation using Fusion's proprietary CDRx (TM) platform and the
production of antibody generating stable cell lines to provide material for
use in clinical trials. Since 2012, the Company has successfully sequenced
and expressed over 250 antibodies and successfully completed over 200
humanisation projects and has an international, blue-chip client base, which
has included eight of the top 10 global pharmaceutical companies by revenue.

 

The Company was established in 2001 as a spin out from Queen's University
Belfast. The Company's mission is to enable pharmaceutical and diagnostic
companies to develop innovative products in a timely and cost-effective manner
for the benefit of the global healthcare industry. Fusion Antibodies provides
a broad range of services in antibody generation, development, production,
characterisation and optimisation.

 

Fusion Antibodies growth strategy is based on combining the latest
technological advances with cutting edge science to deliver new platforms that
will enable Pharma and Biotech companies get to the clinic faster, with the
optimal drug candidate and ultimately speed up the drug development process.

 

The global monoclonal antibody therapeutics market was valued at $135.4
billion in 2018 and is forecast to surpass $212.6 billion in 2022, an increase
at a CAGR of 12.0 per cent. for the period 2018 to 2022. In 2017, seven of the
world's ten top selling drugs were antibody-based therapeutics with the
combined annual sales of these drugs exceeding $63.2 billion.

 

 

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