(Updates)
** Shares of G1 Therapeutics Inc GTHX.O plunge 53.2% to
hit an all-time low of $3.34
** Stock set for its biggest ever intraday pct. drop if
losses hold
** Company says it has decided to discontinue a late-stage
study testing its lead drug for the treatment of a type of colon
cancer
** Placebo outperformed the drug, trilaciclib or Cosela, in
early anti-tumor efficacy data, including overall response rate,
or percentage of patients whose cancer shrinks or disappears
after treatment - GTHX
** The drug was also unlikely to meet the main goals of
extending overall survival or the time that a patient lives
without the disease worsening -GTHX
** The study was testing a combination of the drug
administered along with chemotherapy and Roche's ROG.S therapy
Avastin in patients with a type of colorectal cancer -GTHX
** Including session moves, stock has fallen ~67% in the
past 12 months
(Reporting by Mariam E Sunny)
((Mariam.ESunny@thomsonreuters.com))