** Drugmaker G1 Therapeutics' GTHX.O shares fall 4.7% to
$1.21 premarket
** J.P.Morgan downgrades stock to "underweight" from
"neutral"
** Says they anticipate a Q3 sales miss for co's blood
disorder drug Cosela
** Adds that co's pipeline has more to prove and has faced
too many setbacks
** 6 of 7 brokerages rate the stock "buy" or higher, and 1
"sell" or lower; their median PT is $8 - LSEG data
** Up to last close, stock down 76.6% YTD
(Reporting by Christy Santhosh)
((Christy.Santhosh@thomsonreuters.com))