REG - Genedrive PLC - CYP2C19 kit implemented in North Bristol NHS Trust

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RNS Number : 6446A  Genedrive PLC  16 April 2026

16 April 2026

genedrive plc

("genedrive" or the "Company")

 

Implementation of Genedrive® CYP2C19 ID Kit in North Bristol NHS Trust
Southmead Hospital

 

 

genedrive plc (AIM: GDR), the point of care pharmacogenetic testing company,
is pleased to report that implementation of its CYP2C19 ID kit at Bristol NHS
Trust Southmead Hospital's Hyperacute and Acute Stroke Units is expected to
commence shortly.

 

Southmead Hospital (NHS Bristol, North Somerset and South Gloucestershire
Integrated Care Board (ICB)) treats approximately 1,500 stroke patients per
year, and funding of £80k for the implementation has been provided to it by
the Medlock Charitable Trust (Medlockcharitabletrust.org
(https://medlockcharitabletrust.org/) ), of which David Medlock, a significant
shareholder of genedrive, is Chair.

 

The funding will be administered through Southmead Hospital Charity, the
official charity of North Bristol NHS Trust. The charity has a long-standing
role in supporting enhancements to patient care across the Trust, going beyond
what the NHS alone can provide.

 

Business case preparation by Southmead Stroke Services will progress in
parallel with the aim of securing local ICB funding for the continued
provision of the CYP2C19 test post the initial implementation period.

 

Dr Gino Miele, CEO of genedrive plc, said: "We are grateful to David and the
Medlock Charitable Trust for providing the funding that enables implementation
of our CYP2C19 rapid genetic test at Southmead Hospital. As a result of this
support, stroke patients in the region will immediately benefit from optimised
antiplatelet therapy whilst genedrive continues to engage with the ICB to
secure the longer-term provision of this life saving test."

 

David Medlock, Chair, Medlock Charitable Trust, said: "It's a privilege to
help equip our local NHS stroke medicine service with cutting edge technology
which will not only help patients but also save money."

 

Professor Tim Whittlestone, Bristol NHS Group Chief Medical and Innovation
Officer, said: "We are pleased to have the support of genedrive, which enables
us to introduce point-of-care clopidogrel genotype testing within our service.
This approach to stroke secondary prevention allows for more individualised
treatment decisions, helping us improve long-term outcomes for our diverse
Bristol patient population."

 

 

 genedrive plc
                                                        +44 (0)161 989 0245
 Gino Miele: CEO / Russ Shaw: CFO
                                                        https://investors.genedrive.com/s/e0025c
                                                        (https://investors.genedrive.com/s/e0025c)

 Peel Hunt LLP (Nominated Adviser and Broker)
                                                        +44 (0)20 7418 8900
 James Steel

 5654 & Company  (Media & Investor Relations)           genedrive@5654.co.uk
 Matthew Neal                                           +44 (0)7917 800 011
 Melissa Gardiner                                       +44 (0)7757 697357

 

Subscribe to our news alert service: https://investors.genedrive.com/s/efea03
(https://investors.genedrive.com/s/efea03)

 

About genedrive plc (http://www.genedrive.com (http://www.genedrive.com) ).

 

genedrive plc is a UK-based, commercial-stage pharmacogenetic testing company
focused on rapid, point-of-care diagnostic tests to guide safe and effective
drug prescription in emergency and acute care settings.

 

genedrive's proprietary technology platform enables clinicians to prescribe
safer and more effective therapies based on a patient's genetic profile,
supporting improved outcomes while reducing pressure on healthcare systems,
lowering downstream healthcare costs through the prevention of avoidable
complications and earlier, more effective intervention

 

The Company has two CE-IVD approved and NICE-recommended tests in NHS clinical
use. The Genedrive® CYP2C19 ID Kit identifies stroke patients who will not
respond to the current standard of care, Clopidogrel, used to reduce risk of
secondary stroke. The Genedrive® MT-RNR1 ID Kit helps prevent
antibiotic-induced hearing loss (AIHL) in newborns, enabling treatment
decisions within actionable timeframes at the point of care.

 

Headquartered in Manchester, genedrive is focused on scaling UK-developed
precision diagnostics within routine care and leveraging real-world evidence
to support broader international adoption and commercial growth.

 

 

 

 

 

 

 

 

 

 

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